SCHEMBL5211301

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5212043	0.90	ADORA3 (0.57)	ADORA3NR1I2TBXA2RAGTR1PTGIR
	SCHEMBL5211293	0.89	ADORA3 (0.56)	ADORA3NR1I2TBXA2RAGTR1PTGIR
	SCHEMBL5217815	0.84	ADORA3 (0.45)	ADORA3NR1I2TBXA2RAGTR1PTGIR
	SCHEMBL5214595	0.81	ADORA3 (0.48)	ADORA3NR1I2TBXA2RAGTR1PTGIR
	Laselipag SCHEMBL28689935	0.74	NR1I2 (0.83)	ADORA3NR1I2TBXA2RAGTR1PTGIR
	SCHEMBL5584918	0.74	NR1I2 (0.61)	ADORA3NR1I2TBXA2RAGTR1PTGIR
	SCHEMBL5211664	0.73	PTGIR (0.51)	ADORA3NR1I2TBXA2RAGTR1PTGIR
	SCHEMBL5214486	0.73	PTGIR (0.56)	ADORA3NR1I2TBXA2RAGTR1PTGIR
	Laselipag SCHEMBL30605681	0.72	NR1I2 (0.83)	ADORA3NR1I2TBXA2RAGTR1PTGIR
	SCHEMBL5210867	0.72	NR1I2 (0.77)	ADORA3NR1I2TBXA2RAGTR1PTGIR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.