Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 6/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5238522 | 0.83 | PANK3 (0.43) | PANK3MEN1KMT2AHRH3 | |
| SCHEMBL5237467 | 0.81 | PANK3 (0.40) | PANK3RORCSMOAOC3HDAC1 | |
| SCHEMBL5237139 | 0.80 | RORC (0.37) | RORCAOC3HRH3 | |
| SCHEMBL5236755 | 0.78 | MGLL (0.41) | PANK3KMT2A | |
| SCHEMBL5235191 | 0.77 | ALDH1A1 (0.47) | PANK3 | |
| SCHEMBL5237168 | 0.76 | NPC1 (0.36) | RORCHDAC1MEN1KMT2A | |
| SCHEMBL5238349 | 0.76 | MAPT (0.45) | PANK3MEN1KMT2A | |
| SCHEMBL5233791 | 0.76 | PANK3 (0.41) | PANK3KMT2A | |
| SCHEMBL5234572 | 0.75 | PANK3 (0.55) | PANK3RORCAOC3MEN1KMT2A | |
| SCHEMBL5237292 | 0.75 | KDM4E (0.43) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |