Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA7 | P43166 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | TPMT | P51580 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27700275 | 0.97 | CA2 (0.52) | CA2CA12CA1CA7CA9 | |
| SCHEMBL15178369 | 0.83 | PDE4A (0.50) | TSHRALDH1A1MAPK1PDE4AKDM4E | |
| SCHEMBL8232426 | 0.82 | ACHE (0.46) | CA2CA12CA1CA7CA9 | |
| SCHEMBL14029293 | 0.80 | ACHE (0.39) | CA2CA12CA1CA7CA9 | |
| SCHEMBL15171109 | 0.80 | TTR (0.58) | CA2CA12CA1CA7CA9 | |
| SCHEMBL12998849 | 0.78 | GAA (0.43) | TSHRALDH1A1POLBCYP2C9CYP2C19 | |
| SCHEMBL25648956 | 0.78 | ALDH1A1 (0.61) | TSHRALDH1A1POLBCYP3A4 | |
| SCHEMBL8080493 | 0.78 | AMY1A (0.40) | ALDH1A1MAPK1 | |
| SCHEMBL10212793 | 0.78 | RAB9A (0.50) | ALDH1A1MAPK1TUBB1 | |
| SCHEMBL1809851 | 0.78 | GAA (0.43) | ACHEALDH1A1POLBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11124524-B2 | Diarylethene compounds and uses thereof | SOLUTIA CANADA INC. (US) | 2021-09-21 | — | — | US | disclosed |
| US-10556912-B2 | Diarylethene compounds and uses thereof | SWITCH MATERIALS, INC. (CA) | 2020-02-11 | — | — | US | disclosed |
| US-20190256526-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2019-08-22 | — | — | US | disclosed |
| EP-2809322-B1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | PTC THERAPEUTICS INC (US) | 2019-05-15 | — | — | EP | disclosed |
| WO-2019018795-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2019-01-24 | — | — | WO | disclosed |
| WO-2018129405-A1 | SMALL MOLECULE INHIBITORS OF NEUTRAL SPHINGOMYELINASE 2 (nSMase2) FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-07-12 | — | — | WO | disclosed |
| EP-2927219-B1 | 2-ARYL SELENAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | ATOM BIOSCIENCE AND PHARMACEUTICAL CO LTD (CN) | 2018-05-30 | — | — | EP | disclosed |
| EP-2760969-B1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MAT INC (CA) | 2018-05-16 | — | — | EP | disclosed |
| WO-2018081530-A1 | COMPOSITIONS AND METHODS FOR TREATING EZH2-MEDIATED CANCER | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2018-05-03 | — | — | WO | disclosed |
| CN-107454900-A | Novel imidazo [1,2-A ] quinoxalines and derivatives thereof for the treatment of cancer | 蒙彼利埃大学 | 2017-12-08 | — | — | CN | disclosed |
| WO-2013119916-A2 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | PTC THERAPEUTICS, INC. (US) | 2013-08-15 | — | — | WO | disclosed |
| WO-2013062762-A1 | CAFFEINATED COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF AMYLOID DISEASES AND SYNUCLEINOPATHIES | PROTEOTECH INC (US) | 2013-05-02 | — | — | WO | disclosed |
| US-20130059819-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC. (US) | 2013-03-07 | — | — | US | disclosed |
| US-8349814-B2 | Inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2013-01-08 | — | — | US | disclosed |
| US-20110230440-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | ADAMS JULIAN | 2011-09-22 | — | — | US | disclosed |
| US-7851501-B2 | Aromatic nitrocatechol compounds and their use for modulating processes mediated by cell adhesion molecules | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2010-12-14 | — | — | US | disclosed |
| US-7635181-B2 | Ink for ink jet-recording curable through irradiation with a radioactive ray and method for preparing lithographic printing plates using the same | FUJIFILM CORPORATION (JP) | 2009-12-22 | — | — | US | disclosed |
| US-20090105280-A1 | Novel Aromatic Nitro Compounds | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2009-04-23 | — | — | US | disclosed |
| EP-1543001-B1 | PYRAZOLOPYRIDINE DERIVATIVES AS TGF BETA SIGNAL TRANSDUCTION INHIBITORS FOR THE TREATMENT OF CANCER | LILLY CO ELI (US) | 2007-08-15 | — | — | EP | disclosed |
| EP-1772452-A2 | Matrix metalloproteinase inhibitors and uses thereof | Bristol-Myers Squibb Pharma Company (US) | 2007-04-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256526-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | KCNH2, KCNH3, SCN2B | CA2 2257/4885CA12 2307/4885CA1 2920/4885 |
| US-10556912-B2 | Diarylethene compounds and uses thereof | KCNH2, KCNH3, SCN2B | CA2 2257/4885CA12 2307/4885CA1 2920/4885 |
| US-20090105280-A1 | Novel Aromatic Nitro Compounds | SELP, SELE, SELL | CA2 4231/4885CA12 4570/4885CA1 4799/4885 |
| US-11124524-B2 | Diarylethene compounds and uses thereof | KCNH2, KCNH3, SCN2B | CA2 2257/4885CA12 2307/4885CA1 2920/4885 |
| US-20110230440-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | FAAH, FAAH2, ASAH1 | CA2 1331/4885CA12 1801/4885CA1 908/4885 |
| US-20130059819-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | FAAH, FAAH2, ASAH1 | CA2 1331/4885CA12 1801/4885CA1 908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.