Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 3/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5245644 | 0.90 | LMNA (0.41) | P2RX7LMNADDR1CYP1A2CYP2C19 | |
| SCHEMBL5247031 | 0.88 | LMNA (0.41) | P2RX7LMNAEPHX2PPARGCYP1A2 | |
| SCHEMBL5248524 | 0.87 | LMNA (0.43) | P2RX7LMNAEPHX2PPARGCYP1A2 | |
| SCHEMBL5244456 | 0.84 | LMNA (0.57) | LMNAEPHX2PPARG | |
| SCHEMBL5249308 | 0.83 | RIPK1 (0.46) | LMNACYP1A2CYP2C19CCR1 | |
| SCHEMBL5247130 | 0.83 | CCR1 (0.46) | LMNACYP1A2CYP2D6CYP2C19CCR1 | |
| SCHEMBL5244366 | 0.83 | CCR1 (0.45) | LMNACCR1 | |
| SCHEMBL5246379 | 0.83 | MLYCD (0.50) | LMNACYP1A2CYP2D6CYP2C19CCR1 | |
| SCHEMBL5246999 | 0.83 | HDAC1 (0.46) | LMNAEPHX2PPARGCYP1A2CYP2D6 | |
| SCHEMBL5247254 | 0.83 | HPGD (0.44) | LMNACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |