Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916440 | 0.81 | MAPT (0.41) | MAPTHPGDALDH1A1GLAACHE | |
| SCHEMBL7085947 | 0.74 | ALDH1A1 (0.36) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL558535 | 0.74 | ALDH1A1 (0.46) | MAPTHPGDALDH1A1GLAACHE | |
| SCHEMBL7060124 | 0.69 | ALDH1A1 (0.46) | MAPTHPGDALDH1A1GLAACHE | |
| SCHEMBL558480 | 0.69 | ALDH1A1 (0.46) | MAPTHPGDALDH1A1GLAACHE | |
| SCHEMBL269884 | 0.69 | ALDH1A1 (0.46) | MAPTHPGDALDH1A1GLAACHE | |
| SCHEMBL641339 | 0.69 | ALDH1A1 (0.47) | MAPTHPGDALDH1A1GLAACHE | |
| SCHEMBL521935 | 0.69 | NQO2 (0.46) | MAPTHPGDALDH1A1GLAACHE | |
| SCHEMBL584784 | 0.69 | ALDH1A1 (0.46) | MAPTHPGDALDH1A1GLAACHE | |
| SCHEMBL328898 | 0.69 | ALDH1A1 (0.44) | MAPTHPGDALDH1A1GLAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095043-A1 | TRIOXANE DERIVATIVES | The Hong Kong University of Science & Technology (HK) | 2001-05-02 | — | — | EP | claimed |
| WO-2000004026-A1 | TRIOXANE DERIVATIVES | THE HONG KONG UNIVERSITY OF SCIENCE & TECHNOLOGY (CN) | 2000-01-27 | — | — | WO | claimed |
| EP-0974354-A1 | Artemisinin derivatives | The Hong Kong University of Science & Technology (HK) | 2000-01-26 | — | — | EP | claimed |
| WO-2024111206-A1 | ORGANIC ELECTRONIC ELEMENT AND COMPOUND | 東ソー株式会社 | 2024-05-30 | — | — | WO | disclosed |
| WO-2024105964-A1 | ORGANIC ELECTRONIC ELEMENT AND COMPOUND | 東ソー株式会社 | 2024-05-23 | — | — | WO | disclosed |
| EP-3924341-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | Denali Therapeutics Inc. (US) | 2021-12-22 | — | — | EP | disclosed |
| WO-2020167994-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | DENALI THERAPEUTICS INC. (US) | 2020-08-20 | — | — | WO | disclosed |
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |
| US-9102688-B2 | Sulfonaminoquinoline hepcidin antagonists | VIFOR (INTERNATIONAL) AG (CH) | 2015-08-11 | — | — | US | disclosed |
| US-20140364424-A1 | Novel Sulfonaminoquinoline Hepcidin Antagonists | VIFOR (INTERNATIONAL) AG (CH) | 2014-12-11 | — | — | US | disclosed |
| EP-2675526-A1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | Vifor (International) AG (CH) | 2013-12-25 | — | — | EP | disclosed |
| US-6649647-B1 | Trioxane derivatives | HAYNES RICHARD (CN) | 2003-11-18 | — | — | US | disclosed |
| US-6541466-B2 | Such as 1-(N'-(3,5-difluorophenylacetyl)-L-alaninyl)-aminodibenzosuberane; for treatment of Alzheimer's disease | ATHENA NEUROSCIENCES, INC. | 2003-04-01 | — | — | US | disclosed |
| US-6486153-B1 | Phenylindole derivatives as 5-HT2A receptor ligands | MERCK SHARP & DOHME LTD. | 2002-11-26 | — | — | US | disclosed |
| EP-1095043-A1 | TRIOXANE DERIVATIVES | The Hong Kong University of Science & Technology (HK) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000004026-A1 | TRIOXANE DERIVATIVES | THE HONG KONG UNIVERSITY OF SCIENCE & TECHNOLOGY (CN) | 2000-01-27 | — | — | WO | disclosed |
| EP-0974354-A1 | Artemisinin derivatives | The Hong Kong University of Science & Technology (HK) | 2000-01-26 | — | — | EP | disclosed |
| WO-1999011619-A1 | PHENYLINDOLE DERIVATIVES AS 5-HT2A RECEPTOR LIGANDS | MERCK SHARP & DOHME LIMITED (GB) | 1999-03-11 | — | — | WO | disclosed |
| US-4389403-A | HYPOTENSIVE AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1983-06-21 | — | — | US | disclosed |
| EP-0037471-A1 | 1-Aroyl-2-phenylamino-2-imidazolines, their preparation and their pharmaceutical compositions | BASF Aktiengesellschaft (DE) | 1981-10-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364424-A1 | Novel Sulfonaminoquinoline Hepcidin Antagonists | HAMP, SLC40A1, FTH1 | MAPT 4801/4885HPGD 104/4885ALDH1A1 3570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.