Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LIG1 | P18858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL910763 | 0.81 | HPGD (0.53) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL1988795 | 0.77 | ALDH1A1 (0.48) | HPGDTSHRALDH1A1LMNACYP1A2 | |
| SCHEMBL8968814 | 0.77 | GAA (0.59) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL9115698 | 0.77 | CA1 (0.56) | TSHRMAPK1HSD17B10ALDH1A1LMNA | |
| SCHEMBL93705 | 0.76 | ALDH1A1 (0.56) | HPGDHSD17B10ALDH1A1CYP1A2HTR1A | |
| SCHEMBL1987437 | 0.75 | L3MBTL1 (0.49) | HPGDTSHRALDH1A1LMNACYP1A2 | |
| SCHEMBL9798227 | 0.75 | KDM4E (0.36) | HPGDMAPK1ALDH1A1LMNACYP1A2 | |
| SCHEMBL27641064 | 0.74 | ALDH1A1 (0.54) | HPGDHSD17B10ALDH1A1CYP1A2HTR1A | |
| SCHEMBL525307 | 0.73 | KDM4E (0.34) | HPGDMAPK1ALDH1A1LMNACYP1A2 | |
| SCHEMBL815746 | 0.72 | CYP1A2 (0.47) | ALDH1A1LMNACYP1A2CYP2D6JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797992-B1 | DIGLYCERIN DERIVATE-MODIFIED SILICONE, EMULSIFIER FOR WATER-IN-OIL EMULSION USING THE SAME, EXTERNAL USE PREPARATION, AND COSMETIC COMPOSITION | DOW CORNING TORAY CO LTD (JP) | 2019-04-17 | — | — | EP | disclosed |
| US-10085928-B2 | Diglycerin derivate-modified silicone, emulsifier for water-in-oil emulsion using the same, external use preparaton, and cosmetic composition | DOW CORNING TORAY CO., LTD. (JP) | 2018-10-02 | — | — | US | disclosed |
| US-9585832-B2 | Organopolysiloxane elastomer modified with mono-/diglycerin derivative, and use therefor | DOW CORNING TORAY CO., LTD. (JP) | 2017-03-07 | — | — | US | disclosed |
| US-9480630-B2 | Co-modified organopolysiloxane, emulsifier for water-in-oil emulsion, external use preparation, and cosmetic composition using the same | DOW CORNING TORAY CO., LTD. (JP) | 2016-11-01 | — | — | US | disclosed |
| EP-2598113-B1 | COSMETIC FOR HAIR CONTAINING CO-MODIFIED ORGANOPOLYSILOXANE | DOW CORNING TORAY CO LTD (JP) | 2016-04-20 | — | — | EP | disclosed |
| US-9301913-B2 | Organo polysiloxane elastomer and use therefor | DOW CORNING TORAY CO., LTD. (JP) | 2016-04-05 | — | — | US | disclosed |
| US-20150011656-A1 | Co-Modified Organopolysiloxane, Emulsifier For Water-In-Oil Emulsion, External Use Preparation, And Cosmetic Composition Using The Same | DOW TORAY CO., LTD. (JP) | 2015-01-08 | — | — | US | disclosed |
| US-20150004107-A1 | Diglycerin Derivate-Modified Silicone, Emulsifier For Water-In-Oil Emulsion Using The Same, External Use Preparation, And Cosmetic Composition | DOW TORAY CO., LTD. (JP) | 2015-01-01 | — | — | US | disclosed |
| EP-2797992-A1 | DIGLYCERIN DERIVATE-MODIFIED SILICONE, EMULSIFIER FOR WATER-IN-OIL EMULSION USING THE SAME, EXTERNAL USE PREPARATION, AND COSMETIC COMPOSITION | Dow Corning Toray Co., Ltd. (JP) | 2014-11-05 | — | — | EP | disclosed |
| EP-2797989-A1 | CO-MODIFIED ORGANOPOLYSILOXANE, EMULSIFIER FOR WATER-IN-OIL EMULSION, EXTERNAL USE PREPARATION, AND COSMETIC COMPOSITION USING THE SAME | Dow Corning Toray Co., Ltd. (JP) | 2014-11-05 | — | — | EP | disclosed |
| EP-2563863-A1 | COSMETIC RAW MATERIAL | Dow Corning Corporation (US) | 2013-03-06 | — | — | EP | disclosed |
| US-20130046028-A1 | Cosmetic Raw Material | DOW CORNING TORAY CO., LTD. (JP) | 2013-02-21 | — | — | US | disclosed |
| US-20120328539-A1 | Thickener Or Gellant For Oil Materials, Gel Composition Comprising Same, And Method Of Producing Cosmetic Material Or Topical Agent | DOW TORAY CO., LTD. (JP) | 2012-12-27 | — | — | US | disclosed |
| EP-2516511-A2 | THICKENER OR GELLANT FOR OIL MATERIALS, GEL COMPOSITION COMPRISING SAME, AND METHOD OF PRODUCING COSMETIC MATERIAL OR TOPICAL AGENT | Dow Corning Toray Co., Ltd. (JP) | 2012-10-31 | — | — | EP | disclosed |
| WO-2012015070-A1 | COSMETIC FOR HAIR CONTAINING CO-MODIFIED ORGANOPOLYSILOXANE | DOW CORNING TORAY CO., LTD. (JP) | 2012-02-02 | — | — | WO | disclosed |
| WO-2011137212-A1 | COSMETIC RAW MATERIAL | DOW CORNING CORPORATION (US) | 2011-11-03 | — | — | WO | disclosed |
| US-8034891-B2 | Polyether-modified organopolysiloxane, diorganopolysiloxane-polyether block copolymer, their production methods, and cosmetic preparation | DOW CORNING TORAY COMPANY, LTD. (JP) | 2011-10-11 | — | — | US | disclosed |
| WO-2011078395-A2 | THICKENER OR GELLANT FOR OIL MATERIALS, GEL COMPOSITION COMPRISING SAME, AND METHOD OF PRODUCING COSMETIC MATERIAL OR TOPICAL AGENT | DOW CORNING TORAY CO., LTD. (JP) | 2011-06-30 | — | — | WO | disclosed |
| US-20100036062-A1 | Polyether-Modified Organopolysiloxane, Diorganopolysiloxane-Polyether Block Copolymer, Their Production Methods, and Cosmetic Preparation | DOW TORAY CO., LTD. (JP) | 2010-02-11 | — | — | US | disclosed |
| EP-2022812-A1 | POLYETHER-MODIFIED ORGANOPOLYSILOXANE, DIORGANOPOLYSILOXANE-POLYETHER BLOCK COPOLYMER, THEIR PRODUCTION METHODS, AND COSMETIC PREPARATION | Dow Corning Toray Co., Ltd. (JP) | 2009-02-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120328539-A1 | Thickener Or Gellant For Oil Materials, Gel Composition Comprising Same, And Method Of Producing Cosmetic Material Or Topical Agent | H1-10, F12, RPS12 | HPGD 1740/4885TSHR 3010/4885MAPK1 4309/4885 |
| US-20150011656-A1 | Co-Modified Organopolysiloxane, Emulsifier For Water-In-Oil Emulsion, External Use Preparation, And Cosmetic Composition Using The Same | H1-10, F12, H1-0 | HPGD 2878/4885TSHR 340/4885MAPK1 4511/4885 |
| US-20150004107-A1 | Diglycerin Derivate-Modified Silicone, Emulsifier For Water-In-Oil Emulsion Using The Same, External Use Preparation, And Cosmetic Composition | DGAT1, DGKI, DGAT2 | HPGD 2340/4885TSHR 2163/4885MAPK1 4323/4885 |
| US-20130046028-A1 | Cosmetic Raw Material | LIPA, CUTA, F12 | HPGD 2346/4885TSHR 1243/4885MAPK1 4328/4885 |
| US-10085928-B2 | Diglycerin derivate-modified silicone, emulsifier for water-in-oil emulsion using the same, external use preparaton, and cosmetic composition | PLIN3, PLIN5, DEGS1 | HPGD 1883/4885TSHR 3387/4885MAPK1 4145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.