Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.47 |
| ▸ | IL1RN | P18510 | 1/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL728128 | 0.78 | PGR (0.56) | CA1CA2KEAP1IL1RNERAP1 | |
| SCHEMBL6007495 | 0.77 | CA1 (0.48) | CA1CA2KEAP1IL1RNERAP1 | |
| SCHEMBL6007503 | 0.77 | KEAP1 (0.44) | CA1CA2KEAP1IL1RNERAP1 | |
| SCHEMBL3923476 | 0.77 | CA1 (0.58) | CA1CA2KEAP1IL1RNERAP1 | |
| SCHEMBL6533144 | 0.76 | CA1 (0.56) | CA1CA2KEAP1IL1RNERAP1 | |
| SCHEMBL15672897 | 0.76 | CA2 (0.56) | CA1CA2KEAP1IL1RNERAP1 | |
| SCHEMBL14123868 | 0.75 | RAB9A (0.48) | CA1CA2KEAP1IL1RNERAP1 | |
| SCHEMBL1972989 | 0.74 | HPGD (0.67) | CA1CA2KEAP1IL1RNERAP1 | |
| SCHEMBL10443735 | 0.74 | CA2 (0.54) | CA1CA2KEAP1IL1RNERAP1 | |
| SCHEMBL3763304 | 0.73 | CA1 (0.54) | CA1CA2KEAP1IL1RNERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070238781-A1 | Compounds for the modulation of the glykolysis-enzyme-and/or of the transaminase-complex | EIGENBRODT ERICH | 2007-10-11 | — | — | US | disclosed |
| US-7223784-B2 | Compounds for the modulation of the glycolysis enzyme and/or transaminase complex | ScheBo® Biotech AG (DE) | 2007-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238781-A1 | Compounds for the modulation of the glykolysis-enzyme-and/or of the transaminase-complex | PC, GOT1, PCK1 | CA1 925/4885CA2 776/4885KEAP1 484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.