SCHEMBL536997

SCHEMBL536997

FC(F)(F)C(c1ccccc1)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.41
TSHR P16473 2/20 0.41
F2 P00734 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HTR2A P28223 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
ACP3 P15309 1/20 0.36
CYP2D6 P10635 1/20 0.36
SRC P12931 1/20 0.36
IDO1 P14902 1/20 0.35
TDO2 P48775 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24967234 0.85 RIPK1 (0.38) DPP4TSHRF2ALDH1A1TAAR1
SCHEMBL24967871 0.85 RIPK1 (0.38) DPP4TSHRF2ALDH1A1TAAR1
SCHEMBL22668636 0.85 RIPK1 (0.38) DPP4TSHRF2ALDH1A1TAAR1
SCHEMBL7647445 0.84 ESR1 (0.46)
Phenol SCHEMBL30580405 0.81 ESR1 (0.58) ALDH1A1IDO1TDO2
SCHEMBL7582959 0.80 PGK1 (0.38) TSHRACP3IDO1TDO2
SCHEMBL22624200 0.79 LMNA (0.39) HTR2ATAAR1
SCHEMBL29010088 0.79 CYP2D6 (0.41) ACP3CYP2D6SRC
SCHEMBL10069117 0.77 ESR1 (0.59) DPP4TSHRF2ALDH1A1HTR2A
SCHEMBL7772037 0.74 DPP4 (0.39) DPP4TSHRF2ALDH1A1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 291 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11779911-B2 Production of fatty olefin derivatives via olefin metathesis PROVIVI, INC. (US) 2023-10-10 US claimed
US-20220032280-A1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS PROVIVI, INC. (US) 2022-02-03 US claimed
EP-3019510-B1 USE OF IMMOBILIZED MOLYBDEN- UND TUNGSTEN-CONTAINING CATALYSTS IN OLEFIN CROSS METATHESIS VERBIO VER BIOENERGIE AG (DE) 2020-12-02 EP claimed
EP-3662996-A2 MOLYBDENUM AND TUNGSTEN COMPLEXES AS OLEFIN METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS Verbio Vereinigte BioEnergie AG (DE) 2020-06-10 EP claimed
US-10343153-B2 Metathesis catalysts and reactions using the catalysts XIMO AG (CH) 2019-07-09 US claimed
EP-3377465-A2 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS Provivi, Inc. (US) 2018-09-26 EP claimed
US-10071950-B2 Use of immobilized molybdenum- and tungsten-containing catalysts in olefin cross metathesis XIMO AG (CH) 2018-09-11 US claimed
US-20160159727-A1 USE OF IMMOBILIZED MOLYBDENUM- AND TUNGSTEN-CONTAINING CATALYSTS IN OLEFIN CROSS METATHESIS VERBIO SE (DE) 2016-06-09 US claimed
EP-3019510-A1 USE OF IMMOBILIZED MOLYBDEN- UND TUNGSTEN-CONTAINING CATALYSTS IN OLEFIN CROSS METATHESIS XiMo AG (CH) 2016-05-18 EP claimed
US-20160030936-A1 METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS VERBIO SE (DE) 2016-02-04 US claimed
US-20140309466-A1 METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS VERBIO SE (DE) 2014-10-16 US claimed
WO-2014139679-A2 METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS XIMO AG (CH) 2014-09-18 WO claimed
EP-2703081-A1 Molybdenum and tungsten complexes as olefin metathesis catalysts and reactions using the catalysts XiMo AG (CH) 2014-03-05 EP claimed
WO-2012138844-A2 NON-AQUEOUS ELECTROLYTES FOR LITHIUM-AIR BATTERIES UCHICAGO ARGONNE, LLC (US) 2012-10-11 WO claimed
US-20110034733-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2011-02-10 US claimed
US-7737628-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2010-06-15 US claimed
EP-0866110-B1 Light-emitting material for organo-electroluminescence device and organic electroluminescence device TOYO INK MFG CO (JP) 2004-10-20 EP claimed
EP-0934992-B1 Light-emitting material for organo-electroluminescence device and organic electroluminescence device TOYO INK MFG CO (JP) 2004-07-21 EP claimed
US-6723485-B1 HEXAFLUOROISOPROPYL (METH)ACRYLATE RESIN AND PHOTOACID GENERATOR; LASER HAVING WAVELENGTH IN VACUUM ULTRAVIOLET REGION CENTRAL GLASS COMPANY, LIMITED (JP) 2004-04-20 US claimed
EP-1103856-A1 Positive resist composition & process for forming resist pattern using same Central Glass Company, Limited (JP) 2001-05-30 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10343153-B2 Metathesis catalysts and reactions using the catalysts MSMO1, SQLE, MOGAT2 DPP4 3604/4885TSHR 4219/4885F2 237/4885
US-20140309466-A1 METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS MSMO1, PYM1, SQLE DPP4 4506/4885TSHR 2482/4885F2 156/4885
US-20160030936-A1 METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS MSMO1, SQLE, PYM1 DPP4 4528/4885TSHR 2403/4885F2 159/4885
US-20110034733-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME TYR, DDC, EML4 DPP4 2440/4885TSHR 4212/4885F2 2293/4885
US-20160159727-A1 USE OF IMMOBILIZED MOLYBDENUM- AND TUNGSTEN-CONTAINING CATALYSTS IN OLEFIN CROSS METATHESIS DUOX1, DUOX2, MSN DPP4 4756/4885TSHR 4162/4885F2 746/4885
US-11779911-B2 Production of fatty olefin derivatives via olefin metathesis SREBF1, F2, SREBF2 DPP4 4229/4885TSHR 1977/4885F2 2/4885
US-20220032280-A1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS SREBF1, F2, SREBF2 DPP4 4229/4885TSHR 1977/4885F2 2/4885
US-10071950-B2 Use of immobilized molybdenum- and tungsten-containing catalysts in olefin cross metathesis DUOX1, DUOX2, MSN DPP4 4756/4885TSHR 4162/4885F2 746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.