Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12359218 | 1.00 | NPC1 (0.50) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL17051516 | 0.90 | HPGDS (0.54) | NPC1RAB9APKMHPGDSPIK3CD | |
| SCHEMBL27905344 | 0.90 | HPGDS (0.44) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL9974925 | 0.90 | PTGS2 (0.46) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL17055513 | 0.90 | CYP3A4 (0.49) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL16189444 | 0.90 | L3MBTL1 (0.55) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL17532861 | 0.90 | L3MBTL1 (0.55) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL16189263 | 0.90 | L3MBTL1 (0.55) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL17055531 | 0.87 | HPGDS (0.50) | NPC1RAB9APKMHPGDSCYP2A6 | |
| SCHEMBL676678 | 0.87 | HPGDS (0.56) | NPC1RAB9APKMHPGDSPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 612 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57016862-A | — | — | None | — | — | JP | disclosed |
| US-20260116856-A1 | METHOD FOR PREPARING META-(CHIRAL ALLYL)-SUBSTITUTED PYRIDINE COMPOUND | NANKAI UNIVERSITY (CN) | 2026-04-30 | — | — | US | disclosed |
| US-12540073-B2 | Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor | BRILLIANT LIGHT POWER, INC. (US) | 2026-02-03 | — | — | US | disclosed |
| US-12240812-B2 | Compound for inhibiting PGE2/EP4 signaling transduction inhibiting, preparation method therefor, and medical uses thereof | Keythera (Suzhou) Pharmaceuticals Co. Ltd. (CN) | 2025-03-04 | — | — | US | disclosed |
| CN-115710219-B | Method for preparing meta-cyano-substituted pyridine compound | 南开大学 | 2024-12-03 | — | — | CN | disclosed |
| WO-2024216732-A1 | METHOD FOR PREPARING PYRIDINE COMPOUND WITH META POSITION THEREOF SUBSTITUTED BY CHIRAL ALLYL | 南开大学 | 2024-10-24 | — | — | WO | disclosed |
| CN-116396211-B | Method for preparing meta-chiral allyl substituted pyridine compound | 南开大学 | 2024-10-01 | — | — | CN | disclosed |
| EP-3889134-B1 | COMPOUND FOR INHIBITING PGE2/EP4 SIGNALING TRANSDUCTION INHIBITING, PREPARATION METHOD THEREFOR, AND MEDICAL USES THEREOF | KEYTHERA SUZHOU PHARMACEUTICALS CO LTD (CN) | 2024-09-25 | — | — | EP | disclosed |
| WO-2024144190-A1 | COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | 솔루스첨단소재 주식회사 | 2024-07-04 | — | — | WO | disclosed |
| WO-2024094819-A1 | NEK7 DEGRADERS AND METHODS OF USE THEREOF | CAPTOR THERAPEUTICS S.A. (PL) | 2024-05-10 | — | — | WO | disclosed |
| US-5334600-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1994-08-02 | — | — | US | disclosed |
| WO-1994011378-A1 | ARYL THIOPYRANO[2,3,4-c,d]INDOLES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | MERCK FROSST CANADA INC. (CA) | 1994-05-26 | — | — | WO | disclosed |
| US-5314900-A | Aryl thiopyrano[2,3,4-C,D]indoles as inhibitors of leukotriene biosynthesis | MERCK FROSST CANADA, INC. (CA) | 1994-05-24 | — | — | US | disclosed |
| US-5314898-A | Inhibitors of 5-lipoxygenase | MERCK & CO., INC. (US) | 1994-05-24 | — | — | US | disclosed |
| US-5298486-A | Orange oils for orange juice or seafood flavors | FIRMENICH S.A. (CH) | 1994-03-29 | — | — | US | disclosed |
| US-5202321-A | Antihistamine, antiallergens, antiinflammatory agents | MERCK FROSST CANADA, INC. (CA) | 1993-04-13 | — | — | US | disclosed |
| EP-0518426-A1 | Thiopyrano (2,3,4-c,d) indoles as inhibitors of leukotriene biosynthesis | MERCK FROSST CANADA INC. (CA) | 1992-12-16 | — | — | EP | disclosed |
| US-5004743-A | Antiinflammatory, cytoprotective agents | MERCK FROSST CANADA, INC. (CA) | 1991-04-02 | — | — | US | disclosed |
| EP-0318083-A2 | Pyridyl dialkanoic acids and their use as medicaments | MERCK FROSST CANADA INC. (CA) | 1989-05-31 | — | — | EP | disclosed |
| JP-S5716862-A | 2-ALKYL-5-PHENYLPYRIDINE AND SPICERY COMPOSITION CONTAINING THE SAME | TAKASAGO CORP | 1982-01-28 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260116856-A1 | METHOD FOR PREPARING META-(CHIRAL ALLYL)-SUBSTITUTED PYRIDINE COMPOUND | GAPVD1, TDO2, NOD1 | NPC1 2777/4885RAB9A 514/4885NFKB1 2501/4885 |
| US-12540073-B2 | Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor | SCO2, SOD1, HAO2 | NPC1 3402/4885RAB9A 1741/4885NFKB1 923/4885 |
| US-12240812-B2 | Compound for inhibiting PGE2/EP4 signaling transduction inhibiting, preparation method therefor, and medical uses thereof | PTGER4, PTGER1, PTGES | NPC1 3159/4885RAB9A 4488/4885NFKB1 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.