Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | BMP1 | P13497 | 4/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6430232 | 0.89 | FKBP1A (0.33) | METAP2BMP1MMP2PPARGMEN1 | |
| SCHEMBL5759691 | 0.82 | BMP1 (0.37) | METAP2BMP1MMP2PPARGMEN1 | |
| SCHEMBL5759687 | 0.82 | BMP1 (0.37) | METAP2BMP1MMP2PPARGMEN1 | |
| SCHEMBL6872899 | 0.78 | CYP1A2 (0.36) | BMP1MMP2PPARGPDE4APDE4B | |
| SCHEMBL5403177 | 0.77 | BMP1 (0.36) | METAP2BMP1MMP2PPARGMEN1 | |
| SCHEMBL5403174 | 0.77 | BMP1 (0.36) | METAP2BMP1MMP2PPARGMEN1 | |
| SCHEMBL6872624 | 0.76 | CPB2 (0.34) | BMP1MMP2PPARGPDE4APDE4B | |
| SCHEMBL5408299 | 0.76 | ALDH1A1 (0.36) | BMP1L3MBTL1 | |
| SCHEMBL5421949 | 0.74 | MMP2 (0.37) | BMP1MMP2PPARGKMT2A | |
| SCHEMBL5421875 | 0.74 | METAP2 (0.42) | METAP2BMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214694-B2 | 3-ox(adi)azolylpropanohydroxamic acids useful as procollagen C-proteinase inhibitors | PFIZER INC (US) | 2007-05-08 | — | — | US | disclosed |
| US-20040142986-A1 | 3-ox(adi)azolylpropanohydroxamic acids useful as procollagen C-proteinase inhibitors | DATTA USA (GB) | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142986-A1 | 3-ox(adi)azolylpropanohydroxamic acids useful as procollagen C-proteinase inhibitors | ALPI, TIMP3, MMP1 | METAP2 532/4885BMP1 376/4885MMP2 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.