Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | AKT2 | P31751 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PI4KA | P42356 | 1/20 | 0.49 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.49 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.49 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13052922 | 0.88 | PDE10A (0.56) | PDE10AMEN1KMT2APOLBPABPC1 | |
| SCHEMBL7364877 | 0.85 | PDE10A (0.57) | PDE10AMEN1KMT2APOLBPABPC1 | |
| SCHEMBL13052928 | 0.84 | TP53 (0.51) | MAPK1HTTPDE10AMEN1KMT2A | |
| SCHEMBL13052984 | 0.82 | AKT1 (0.53) | MAPK1HTTPDE10AMEN1KMT2A | |
| SCHEMBL804898 | 0.82 | AKT1 (0.53) | MAPK1HTTPDE10AMEN1KMT2A | |
| SCHEMBL9726854 | 0.82 | PDE4B (0.55) | PDE10AMEN1KMT2APOLBPABPC1 | |
| SCHEMBL804897 | 0.81 | ALDH1A1 (0.60) | MEN1KMT2APOLBPABPC1MAPT | |
| SCHEMBL8805096 | 0.81 | ALDH1A1 (0.64) | MEN1KMT2APOLBPABPC1MAPT | |
| SCHEMBL17077773 | 0.81 | MEN1 (0.60) | MAPK1PDE10AMEN1KMT2APOLB | |
| SCHEMBL12853962 | 0.80 | AKT1 (0.63) | MEN1KMT2APOLBPABPC1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735586-B2 | Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles | SANOFI (FR) | 2014-05-27 | — | — | US | claimed |
| EP-2044033-B1 | A REGIOSELECTIVE PALLADIUM CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES | SANOFI SA (FR) | 2012-02-08 | — | — | EP | claimed |
| EP-2173721-B1 | A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES | SANOFI SA (FR) | 2011-12-28 | — | — | EP | claimed |
| US-20100261909-A1 | Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles | SANOFI-AVENTIS (FR) | 2010-10-14 | — | — | US | claimed |
| US-20090203912-A1 | Regioselective palladium catalyzed synthesis of benzimidazoles and azabenzimidazoles | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | US | claimed |
| EP-1878724-A1 | A regioselective palladium catalyzed synthesis of benzimidazoles and azabenzimidazoles | sanofi-aventis (FR) | 2008-01-16 | — | — | EP | claimed |
| US-20210202864-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT | KYULUX, INC. (JP) | 2021-07-01 | — | — | US | disclosed |
| EP-3843167-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT | Kyushu University, National University Corporation (JP) | 2021-06-30 | — | — | EP | disclosed |
| US-20200235313-A1 | COMPOUND, LIGHT-EMITTING MATERIAL AND LIGHT-EMITTING ELEMENT | KYULUX, INC. (JP) | 2020-07-23 | — | — | US | disclosed |
| US-10547014-B2 | Composition of matter for use in organic light-emitting diodes | KYULUX, INC. (JP) | 2020-01-28 | — | — | US | disclosed |
| US-20190006606-A1 | COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES | Kyulux North America, Inc. | 2019-01-03 | — | — | US | disclosed |
| US-20170148996-A1 | ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC OPTOELECTRONIC DEVICES COMPRISING THE SAME | WUHAN TIANMA MICROELECTRONICS CO., LTD.SHANGHAI BRANCH (CN) | 2017-05-25 | — | — | US | disclosed |
| US-20170148996-A1 | ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC OPTOELECTRONIC DEVICES COMPRISING THE SAME | WUHAN TIANMA MICROELECTRONICS CO., LTD.SHANGHAI BRANCH (CN) | 2017-05-25 | — | — | US | disclosed |
| US-20090203912-A1 | Regioselective palladium catalyzed synthesis of benzimidazoles and azabenzimidazoles | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | US | disclosed |
| US-20090203912-A1 | Regioselective palladium catalyzed synthesis of benzimidazoles and azabenzimidazoles | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | US | disclosed |
| WO-2009000413-A1 | A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES | SANOFI-AVENTIS (FR) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009000413-A1 | A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES | SANOFI-AVENTIS (FR) | 2008-12-31 | — | — | WO | disclosed |
| WO-2008009348-A1 | A REGIOSELECTIVE PALLADIUM CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES | SANOFI-AVENTIS (FR) | 2008-01-24 | — | — | WO | disclosed |
| EP-1878724-A1 | A regioselective palladium catalyzed synthesis of benzimidazoles and azabenzimidazoles | sanofi-aventis (FR) | 2008-01-16 | — | — | EP | disclosed |
| EP-1878724-A1 | A regioselective palladium catalyzed synthesis of benzimidazoles and azabenzimidazoles | sanofi-aventis (FR) | 2008-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10547014-B2 | Composition of matter for use in organic light-emitting diodes | CRY2, ALDH1A2, CYBA | MAPK1 4648/4885HTT 1733/4885PDE10A 3396/4885 |
| US-20100261909-A1 | Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles | AZI2, NISCH, UQCRB | MAPK1 3459/4885HTT 3225/4885PDE10A 3849/4885 |
| US-20190006606-A1 | COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES | CRY2, ALDH1A2, CYBA | MAPK1 4648/4885HTT 1733/4885PDE10A 3396/4885 |
| US-20200235313-A1 | COMPOUND, LIGHT-EMITTING MATERIAL AND LIGHT-EMITTING ELEMENT | LBR, CTNND1, NCL | MAPK1 3977/4885HTT 1638/4885PDE10A 4697/4885 |
| US-20090203912-A1 | Regioselective palladium catalyzed synthesis of benzimidazoles and azabenzimidazoles | DDT, NIT2, PADI1 | MAPK1 3566/4885HTT 2283/4885PDE10A 1638/4885 |
| US-20170148996-A1 | ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC OPTOELECTRONIC DEVICES COMPRISING THE SAME | OR10J3, PPOX, OR51E2 | MAPK1 2046/4885HTT 3627/4885PDE10A 1929/4885 |
| US-20210202864-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT | LEF1, EMC1, EEA1 | MAPK1 462/4885HTT 3904/4885PDE10A 4204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.