Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | ACP3 | P15309 | 2/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5413664 | 0.88 | TAAR1 (0.52) | AOC3TAAR1 | |
| SCHEMBL5488878 | 0.80 | LTA4H (0.43) | — | |
| SCHEMBL5490217 | 0.79 | IDO1 (0.38) | AOC3 | |
| SCHEMBL5494536 | 0.78 | ACHE (0.44) | GRIA4AOC3 | |
| SCHEMBL11758612 | 0.78 | GRIA4 (0.50) | GRIA4PTGS2CHRNB2CHRNA4AOC3 | |
| SCHEMBL5484319 | 0.78 | ADRB2 (0.46) | AOC3 | |
| SCHEMBL5487989 | 0.76 | PYCR1 (0.37) | — | |
| SCHEMBL5489949 | 0.76 | AOC3 (0.35) | AOC3CYP17A1 | |
| SCHEMBL11209510 | 0.75 | TAAR1 (0.52) | AOC3TAAR1 | |
| SCHEMBL3628638 | 0.75 | GRIA4 (0.51) | GRIA4PTGS2CHRNB2CHRNA4TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |