Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6256819 | 0.79 | HSD17B10 (0.44) | HSD17B10ALOX15TDP1FGFR1HTT | |
| SCHEMBL15022038 | 0.78 | TDP1 (0.52) | HSD17B10ALOX15TDP1FGFR1HTT | |
| SCHEMBL4258614 | 0.75 | ALDH1A1 (0.46) | HSD17B10ALOX15TDP1FGFR1HTT | |
| SCHEMBL1488096 | 0.75 | TDP1 (0.48) | HSD17B10ALOX15TDP1FGFR1HTT | |
| SCHEMBL1800353 | 0.75 | TDP1 (0.48) | HSD17B10ALOX15TDP1FGFR1HTT | |
| SCHEMBL15401045 | 0.74 | TDP1 (0.48) | HSD17B10ALOX15TDP1HTTCYP1A2 | |
| SCHEMBL204727 | 0.73 | ALOX15 (0.64) | HSD17B10ALOX15FGFR1HTTCYP1A2 | |
| SCHEMBL9631161 | 0.73 | NPSR1 (0.47) | HTTSMN1; SMN2POLB | |
| SCHEMBL239691 | 0.72 | HTT (0.48) | HSD17B10ALOX15TDP1HTTCYP1A2 | |
| SCHEMBL707209 | 0.71 | ALOX15 (0.58) | HSD17B10ALOX15TDP1FGFR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110294754-A | Pyrido benzimidazole cysteine ratio probes and its application | 泰山医学院 | 2019-10-01 | — | — | CN | claimed |
| CN-101212903-B | Polycyclic carbamoylpyridone derivatives having HIV integrase inhibitory activity | SHIONOGI & CO | 2013-07-24 | — | — | CN | claimed |
| CN-101212903-A | Polycyclic carbamoylpyridone derivatives having HIV integrase inhibitory activity | SMITHKLINE BEECHAM CORP (US) | 2008-07-02 | — | — | CN | claimed |
| EP-1063235-B1 | BENZOFURYLPYRONE DERIVATIVES | TEIJIN LTD (JP) | 2004-05-12 | — | — | EP | claimed |
| US-20030186976-A1 | Benzofurylpyrone derivatives | TEIJIN LIMITED, MICROBIAL CHEMISTRY RESEARCH FOUNDATION | 2003-10-02 | — | — | US | claimed |
| EP-1063235-A1 | BENZOFURYLPYRONE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-12-27 | — | — | EP | claimed |
| CN-110294754-A | Pyrido benzimidazole cysteine ratio probes and its application | 泰山医学院 | 2019-10-01 | — | — | CN | disclosed |
| CN-110294754-A | Pyrido benzimidazole cysteine ratio probes and its application | 泰山医学院 | 2019-10-01 | — | — | CN | disclosed |
| CN-105646331-B | Piperidine compounds, the medical composition and its use containing the compound | 爱思开生物制药株式会社 | 2018-07-03 | — | — | CN | disclosed |
| CN-107744795-A | A kind of hydrogenation-dechlorination catalyst converter | 徐州工程学院 | 2018-03-02 | — | — | CN | disclosed |
| WO-2015073736-A1 | METHODS AND COMPOSITIONS FOR TREATING ADHD | ARBOR PHARMACEUTICALS, LLC (US) | 2015-05-21 | — | — | WO | disclosed |
| US-20150133516-A1 | Methods and Compositions for Treating ADHD | ARBOR PHARMACEUTICALS, INC. | 2015-05-14 | — | — | US | disclosed |
| CN-101212903-B | Polycyclic carbamoylpyridone derivatives having HIV integrase inhibitory activity | SHIONOGI & CO | 2013-07-24 | — | — | CN | disclosed |
| US-4283486-A | DISCOLORATION INHIBITION | FUJI PHOTO FILM CO., LTD. (JP) | 1981-08-11 | — | — | US | disclosed |
| US-4264722-A | A COLORLESS CYAN-COLOR-FORMING COUPLER COMPRISING 4-OXY-DERIVATIVES OF 1-HYDROXY-2-SEC-AMIDO-NAPHTHALENE OR BENZENE | FUJI PHOTO FILM CO., LTD. (JP) | 1981-04-28 | — | — | US | disclosed |
| US-4254212-A | ALKOXY SUBSTITUTED SULFONYL | FUJI PHOTO FILM CO., LTD. (JP) | 1981-03-03 | — | — | US | disclosed |
| US-4228233-A | CYAN DYE FORMING, COLORLESS COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1980-10-14 | — | — | US | disclosed |
| US-4217410-A | CYAN DYE COUPLER, PHOSPHATE SOLVENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1980-08-12 | — | — | US | disclosed |
| US-4072525-A | COLOR PHOTOGRAPHY | FUJI PHOTO FILM CO., LTD. (JA) | 1978-02-07 | — | — | US | disclosed |
| US-4032345-A | SILVER HALIDE MATERIALS CONTAINING PHOTOGRAPHIC COLOR COUPLERS WITH ISOTHIOCYANATO GROUPS | FUJI PHOTO FILM CO., LTD. (JA) | 1977-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133516-A1 | Methods and Compositions for Treating ADHD | ADRA2C, ADRA2A, ADRB2 | HSD17B10 1069/4885ALOX15 1839/4885TDP1 2064/4885 |
| US-20030186976-A1 | Benzofurylpyrone derivatives | PLIN5, ACSL5, PLIN1 | HSD17B10 25/4885ALOX15 418/4885TDP1 1261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.