Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL174937 | 0.81 | ALDH1A1 (0.48) | GAAKMT2AMEN1LMNATHRB | |
| SCHEMBL10279067 | 0.80 | LMNA (0.43) | GAAKMT2AMEN1LMNATHRB | |
| SCHEMBL5459629 | 0.80 | GAA (0.47) | GAAKMT2ALMNATSHRHTT | |
| SCHEMBL11085020 | 0.79 | SMN1; SMN2 (0.39) | KMT2AMEN1LMNATHRBBLM | |
| SCHEMBL6328702 | 0.79 | CTSD (0.50) | GAAKMT2AMEN1LMNATHRB | |
| SCHEMBL14185996 | 0.79 | MAOB (0.47) | KMT2AMEN1BLMTSHRHTT | |
| SCHEMBL16157270 | 0.78 | KMT2A (0.41) | KMT2AMEN1LMNATHRBBLM | |
| SCHEMBL3093204 | 0.78 | CYP1A2 (0.42) | KMT2AMEN1LMNATHRBBLM | |
| SCHEMBL10117106 | 0.78 | KMT2A (0.49) | KMT2AMEN1LMNATHRBBLM | |
| SCHEMBL15728763 | 0.78 | KEAP1 (0.53) | GAAKMT2AMEN1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001035899-A9 | INHIBITORS OF HELICOBACTER PYLORI INDUCED GASTROINTESTINAL DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-09-19 | — | — | WO | claimed |
| EP-1229925-A2 | INHIBITORS OF HELICOBACTER PYLORI INDUCED GASTROINTESTINAL DISEASES | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2002-08-14 | — | — | EP | claimed |
| WO-2001035899-A2 | INHIBITORS OF HELICOBACTER PYLORI INDUCED GASTROINTESTINAL DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2001-05-25 | — | — | WO | claimed |
| EP-2867205-B1 | NOVEL CHOLECYSTOKININ RECEPTOR LIGANDS | PNB VESPER LIFE SCIENCE PVT LTD (IN) | 2018-12-19 | — | — | EP | disclosed |
| EP-2867205-A1 | NOVEL CHOLECYSTOKININ RECEPTOR LIGANDS | PNB Vesper Life Science Pvt Limited (IN) | 2015-05-06 | — | — | EP | disclosed |
| US-8921577-B2 | Cholecystokinin receptor ligands | PNB Vesper Life Sciences Pvt. Ltd. (IN) | 2014-12-30 | — | — | US | disclosed |
| WO-2014006629-A1 | NOVEL CHOLECYSTOKININ RECEPTOR LIGANDS | PNB VESPER LIFE SCIENCE PVT LIMITED (IN) | 2014-01-09 | — | — | WO | disclosed |
| US-20140005248-A1 | NOVEL CHOLECYSTOKININ RECEPTOR LIGANDS | PNB VESPER LIFE SCIENCES PVT LTD. (IN) | 2014-01-02 | — | — | US | disclosed |
| US-20070185094-A1 | Novel 3-substitued-1,4-benzodiazepines | ASTON UNIVERSITY (GB) | 2007-08-09 | — | — | US | disclosed |
| US-20070185115-A1 | Novel ureido-and amido-pyrazolone derivatives | ASTON UNIVERSITY (GB) | 2007-08-09 | — | — | US | disclosed |
| US-20070123718-A1 | Novel 4-amino-2(5H)-furanones | ASTON UNIVERSITY (GB) | 2007-05-31 | — | — | US | disclosed |
| EP-1636197-A1 | NOVEL 3-SUBSTITUTED-1,4-BENZODIAZEPINES | Aston University (GB) | 2006-03-22 | — | — | EP | disclosed |
| EP-1628963-A1 | NOVEL UREIDO - AND AMIDO-PYRAZOLONE DERIVATIVES | Aston University (GB) | 2006-03-01 | — | — | EP | disclosed |
| EP-1628966-A2 | 4-AMINO-2(5H)-FURANONES USEFUL AS CHOLECYSTOKININ ANTAGONISTS | Aston University (GB) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004106310-A1 | NOVEL 3-SUBSTITUTED-1,4-BENZODIAZEPINES | ASTON UNIVERSITY (GB) | 2004-12-09 | — | — | WO | disclosed |
| WO-2004106306-A1 | NOVEL UREIDO - AND AMIDO-PYRAZOLONE DERIVATIVES | ASTON UNIVERSITY (GB) | 2004-12-09 | — | — | WO | disclosed |
| WO-2004106315-A2 | 4-AMINO-2(5H)-FURANONES USEFUL AS CHOLECYSTOKININ ANTAGONISTS | ASTON UNIVERSITY (GB) | 2004-12-09 | — | — | WO | disclosed |
| WO-2001035899-A9 | INHIBITORS OF HELICOBACTER PYLORI INDUCED GASTROINTESTINAL DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-09-19 | — | — | WO | disclosed |
| EP-1229925-A2 | INHIBITORS OF HELICOBACTER PYLORI INDUCED GASTROINTESTINAL DISEASES | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001035899-A2 | INHIBITORS OF HELICOBACTER PYLORI INDUCED GASTROINTESTINAL DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2001-05-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185115-A1 | Novel ureido-and amido-pyrazolone derivatives | CCKAR, CCKBR, GRPR | GAA 4658/4885KMT2A 4491/4885MEN1 3287/4885 |
| US-20070185094-A1 | Novel 3-substitued-1,4-benzodiazepines | CCKBR, CCKAR, GABRB1 | GAA 2957/4885KMT2A 2120/4885MEN1 2746/4885 |
| US-20140005248-A1 | NOVEL CHOLECYSTOKININ RECEPTOR LIGANDS | CCKAR, CCKBR, GRPR | GAA 4606/4885KMT2A 3141/4885MEN1 3472/4885 |
| US-20070123718-A1 | Novel 4-amino-2(5H)-furanones | CBR1, CBR3, GPR18 | GAA 4780/4885KMT2A 3361/4885MEN1 3224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.