SCHEMBL547291

SCHEMBL547291

C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2OC(=O)c1cccnc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 8/20 0.64
▸ LMNA P02545 8/20 0.64
▸ TSHR P16473 5/20 0.64
▸ MAPT P10636 5/20 0.64
▸ CYP17A1 P05093 4/20 0.64
▸ NR3C1 P04150 4/20 0.64
▸ PGR P06401 4/20 0.64
▸ AR P10275 4/20 0.64
▸ NR1I2 O75469 3/20 0.64
▸ CYP2C9 P11712 3/20 0.64
▸ CYP2C19 P33261 2/20 0.64
▸ OPRK1 P41145 1/20 0.64
▸ CYP19A1 P11511 4/20 0.63
▸ CYP21A2 P08686 1/20 0.57
▸ HSD17B10 Q99714 4/20 0.55
▸ SHBG P04278 4/20 0.55
▸ SERPINA6 P08185 4/20 0.55
▸ MAPK1 P28482 4/20 0.55
▸ GPBAR1 Q8TDU6 3/20 0.55
▸ SIGMAR1 Q99720 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6898510 1.00 CYP3A4 (0.64) CYP3A4LMNATSHRMAPTCYP17A1
SCHEMBL6901756 0.89 CYP3A4 (0.68) CYP3A4LMNATSHRMAPTCYP17A1
SCHEMBL6901750 0.89 CYP3A4 (0.68) CYP3A4LMNATSHRMAPTCYP17A1
SCHEMBL4264019 0.89 CYP3A4 (0.71) CYP3A4LMNATSHRMAPTCYP17A1
SCHEMBL4264017 0.89 CYP3A4 (0.71) CYP3A4LMNATSHRMAPTCYP17A1
SCHEMBL6902011 0.85 CYP3A4 (0.65) CYP3A4LMNATSHRMAPTCYP17A1
SCHEMBL6902019 0.85 CYP3A4 (0.65) CYP3A4LMNATSHRMAPTCYP17A1
SCHEMBL6902015 0.85 CYP3A4 (0.65) CYP3A4LMNATSHRMAPTCYP17A1
SCHEMBL6902002 0.85 CYP3A4 (0.65) CYP3A4LMNATSHRMAPTCYP17A1
SCHEMBL6897111 0.84 CYP3A4 (0.69) CYP3A4LMNATSHRMAPTCYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 216 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180169069-A1 COMPOSITIONS AND METHODS FOR AMELIORATING CACHEXIA VICUS THERAPEUTICS LLC (US) 2018-06-21 — — US claimed
US-8110565-B2 Of the ACE inhibitor ramipril; controlling the melting point by mixing with the free acid with the ramipril ethyl or methyl ester prodrug and a pressure sensitive adhesive carrier; improved pharmacokinetics; sustained release NOVEN PHARMACEUTICALS, INC. (US) 2012-02-07 — — US claimed
EP-2374458-A1 Combination of an ACE inhibitor and an NSAID for use in ameliorating cachexia/SIRS Vicus Therapeutics SPE 1, LLC (US) 2011-10-12 — — EP claimed
EP-2374508-A1 Combination of angiotension receptor blockers (ARB) and NSAIDs for use in ameliorating cachexia Vicus Therapeutics SPE 1, LLC (US) 2011-10-12 — — EP claimed
US-7846916-B2 Enhanced drug delivery in transdermal systems Noven Pharamaceticals, Inc. (US) 2010-12-07 — — US claimed
US-20090215852-A1 COMPOSITIONS AND METHODS FOR AMELIORATING CACHEXIA CHROMA GROUP, INC. 2009-08-27 — — US claimed
US-20090117197-A1 COMPOSITIONS AND METHODS FOR AMELIORATING CACHEXIA VICUS THERAPEUTICS LLC (US) 2009-05-07 — — US claimed
EP-1990049-A2 Combination therapy of beta-blockers and non-steroidal anti-inflammatory drugs (NSAID) Vicus Therapeutics SPE 1, LLC (US) 2008-11-12 — — EP claimed
US-20080167280-A1 Enhanced drug delivery in transdermal systems NOVEN PHARMACEUTICALS, INC. 2008-07-10 — — US claimed
EP-1865779-A4 COMPOSITIONS AND METHODS FOR AMELIORATING CACHEXIA VICUS THERAPEUTICS SPE 1 LLC (US) 2008-06-04 — — EP claimed
CN-100391462-C Enhanced drug delivery in transdermal systems NOVEN PHARMA (US) 2008-06-04 — — CN claimed
EP-1865779-A2 COMPOSITIONS AND METHODS FOR AMELIORATING CACHEXIA Vicus Therapeutics SPE 1, LLC (US) 2007-12-19 — — EP claimed
US-7214381-B2 Composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels ANTARES PHARMA IPL AG (CH) 2007-05-08 — — US claimed
WO-2006102476-A2 COMPOSITIONS AND METHODS FOR AMELIORATING CACHEXIA VICUS THERAPEUTICS SPE 1, LLC (US) 2006-09-28 — — WO claimed
EP-0801561-B1 COMPOSITION AND METHODS FOR TRANSDERMAL DELIVERY OF ACID-LABILE DRUGS NOVEN PHARMA (US) 2005-04-06 — — EP claimed
US-20040235808-A1 Androstanes as androgen receptor modulators WANG JIABING (US) 2004-11-25 — — US claimed
EP-1429779-A2 ANDROSTANES AS ANDROGEN RECEPTOR MODULATORS Merck & Co., Inc. (US) 2004-06-23 — — EP claimed
WO-2003026568-A2 ANDROSTANES AS ANDROGEN RECEPTOR MODULATORS MERCK & CO., INC. (US) 2003-04-03 — — WO claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 — — CN claimed
US-20260014080-A1 LIPOSOMAL PREPARATION WITH ENCAPSULATED HORMONES, METHOD OF PRODUCTION AND USE THEREOF VAN BOGAERT GINA (BE) 2026-01-15 — — US disclosed
US-20250281509-A1 SEQUENTIAL HORMONE THERAPY TO IMPROVE SURVIVAL AND ENHANCE RESPONSE TO IMMUNE THERAPY IN MEN WITH PROSTATE CANCER THE JOHNS HOPKINS UNIVERSTY 2025-09-11 — — US disclosed
WO-2025054607-A1 COMPOSITIONS AND METHODS FOR TREATING SARCOPENIA THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-03-13 — — WO disclosed
US-20250032509-A1 Testosterone Ester Triglyceride Formulations ANTARES PHARMA, INC. (US) 2025-01-30 — — US disclosed
US-12144817-B2 Testosterone ester triglyceride formulations ANTARES PHARMA, INC. (US) 2024-11-19 — — US disclosed
EP-3335740-B1 MEDICAL HYDROGEL UPM KYMMENE CORP (FI) 2024-07-24 — — EP disclosed
US-20230416822-A1 DETECTION AND TREATMENT OF CONDITIONS CHARACTERIZED BY PERFUSION SHORTAGE FALCON BIOSCIENCE, LLC 2023-12-28 — — US disclosed
US-11850306-B2 Method for drying hydrogel comprising nanofibrillar cellulose and a dried hydrogel comprising nanofibrillar cellulose UPM-KYMMENE CORPORATION (FI) 2023-12-26 — — US disclosed
WO-2023223235-A1 LIPOSOMAL PREPARATION WITH ENCAPSULATED HORMONES, METHOD OF PRODUCTION AND USE THEREOF PURNA PHARMACEUTICALS NV (BE) 2023-11-23 — — WO disclosed
EP-4153995-A2 DETECTION AND TREATMENT OF CONDITIONS CHARACTERIZED BY PERFUSION SHORTAGE Falcon Bioscience, LLC (US) 2023-03-29 — — EP disclosed
US-11534526-B2 Medical hydrogel UPM-KYMMENE CORPORATION (FI) 2022-12-27 — — US disclosed
CN-110087633-B Method for drying hydrogel comprising nanofibrillar cellulose and dried hydrogel comprising nanofibrillar cellulose 芬欧汇川集团 2022-08-09 — — CN disclosed
CN-110072567-B Medical hydrogel 芬欧汇川集团 2022-04-12 — — CN disclosed
US-20220079955-A1 Testosterone Ester Triglyceride Formulations ANTARES PHARMA, INC. (US) 2022-03-17 — — US disclosed
WO-2021236836-A2 DETECTION AND TREATMENT OF CONDITIONS CHARACTERIZED BY PERFUSION SHORTAGE FALCON BIOSCIENCE, LLC (US) 2021-11-25 — — WO disclosed
US-11123352-B2 Testosterone ester triglyceride formulations ANTARES PHARMA, INC. (US) 2021-09-21 — — US disclosed
US-20200289528-A1 Testosterone Ester Triglyceride Formulations ANTARES PHARMA, INC. (US) 2020-09-17 — — US disclosed
EP-3675868-A1 TESTOSTERONE ESTER TRIGLYCERIDE FORMULATIONS Antares Pharma, Inc. (US) 2020-07-08 — — EP disclosed
US-20200197310-A1 Technology for Preparation of Macromolecular Microspheres NEXBIO, INC. 2020-06-25 — — US disclosed
US-10646495-B2 Testosterone ester triglyceride formulations ANTARES PHARMA, INC. (US) 2020-05-12 — — US disclosed
US-20200078305-A1 A METHOD FOR DRYING HYDROGEL COMPRISING NANOFIBRILLAR CELLULOSE AND A DRIED HYDROGEL COMPRISING NANOFIBRILLAR CELLULOSE UPM-KYMMENE CORPORATION (FI) 2020-03-12 — — US disclosed
US-10583086-B2 Technology for preparation of macromolecular microspheres ANSUN BIOPHARMA, INC. (US) 2020-03-10 — — US disclosed
EP-3335695-B1 A METHOD FOR FREEZE-DRYING HYDROGEL COMPRISING NANOFIBRILLAR CELLULOSE, A FREEZE-DRIED MEDICAL HYDROGEL COMPRISING NANOFIBRILLAR CELLULOSE, AND A HYDROGEL COMPRISING NANOFIBRILLAR CELLULOSE UPM KYMMENE CORP (FI) 2020-02-05 — — EP disclosed
EP-3335696-B1 A METHOD FOR DRYING CELL-FREE TISSUE EXTRACT IN A HYDROGEL COMPRISING NANOFIBRILLAR CELLULOSE AND A DRIED HYDROGEL COMPRISING NANOFIBRILLAR CELLULOSE AND CELL-FREE TISSUE EXTRACT UPM KYMMENE CORP (FI) 2019-12-18 — — EP disclosed
US-20190343889-A1 A METHOD FOR DRYING CELL-FREE TISSUE EXTRACT IN A HYDROGEL COMPRISING NANOFIBRILLAR CELLULOSE AND A DRIED HYDROGEL COMPRISING NANOFIBRILLAR CELLULOSE AND CELL-FREE TISSUE EXTRACT UPM KYMMENE CORP (FI) 2019-11-14 — — US disclosed
US-20190336643-A1 MEDICAL HYDROGEL UPM-KYMMENE CORPORATION (FI) 2019-11-07 — — US disclosed
CN-110234314-A The method of dry acellular tissue extract and the dried hydrogel comprising nanometer fibril cellulose and acellular tissue extract in the hydrogel comprising nanometer fibril cellulose 芬欧汇川集团 2019-09-13 — — CN disclosed
CN-110087633-A The method of the dry hydrogel comprising nanometer fibril cellulose and the hydrogel of the drying comprising nanometer fibril cellulose 芬欧汇川集团 2019-08-02 — — CN disclosed
CN-110072567-A Medical aquogel 芬欧汇川集团 2019-07-30 — — CN disclosed
WO-2019046582-A1 TESTOSTERONE ESTER TRIGLYCERIDE FORMULATIONS ANTARES PHARMA, INC. (US) 2019-03-07 — — WO disclosed
US-20190000802-A1 DRUG COMBINATION PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USING THEM VICUS THERAPEUTICS LLC (US) 2019-01-03 — — US disclosed
US-20180169069-A1 COMPOSITIONS AND METHODS FOR AMELIORATING CACHEXIA VICUS THERAPEUTICS LLC (US) 2018-06-21 — — US disclosed
WO-2018109281-A1 A METHOD FOR DRYING HYDROGEL COMPRISING NANOFIBRILLAR CELLULOSE AND A DRIED HYDROGEL COMPRISING NANOFIBRILLAR CELLULOSE UPM-KYMMENE CORPORATION (FI) 2018-06-21 — — WO disclosed
WO-2018109282-A1 A METHOD FOR DRYING CELL-FREE TISSUE EXTRACT IN A HYDROGEL COMPRISING NANOFIBRILLAR CELLULOSE AND A DRIED HYDROGEL COMPRISING NANOFIBRILLAR CELLULOSE AND CELL-FREE TISSUE EXTRACT UPM-KYMMENE CORPORATION (FI) 2018-06-21 — — WO disclosed
EP-3335696-A1 A METHOD FOR DRYING CELL-FREE TISSUE EXTRACT IN A HYDROGEL COMPRISING NANOFIBRILLAR CELLULOSE AND A DRIED HYDROGEL COMPRISING NANOFIBRILLAR CELLULOSE AND CELL-FREE TISSUE EXTRACT UPM-Kymmene Corporation (FI) 2018-06-20 — — EP disclosed
EP-3335695-A1 A METHOD FOR DRYING HYDROGEL COMPRISING NANOFIBRILLAR CELLULOSE AND A DRIED HYDROGEL COMPRISING NANOFIBRILLAR CELLULOSE UPM-Kymmene Corporation (FI) 2018-06-20 — — EP disclosed
US-20180071219-A1 Technology for Preparation of Macromolecular Microspheres NEXBIO, INC. 2018-03-15 — — US disclosed
US-20180028449-A1 Technology for the Preparation of Microparticles NEXBIO, INC. 2018-02-01 — — US disclosed
US-20170333396-A1 COMPOSITIONS AND METHODS FOR AMELIORATING CACHEXIA VICUS THERAPEUTICS LLC (US) 2017-11-23 — — US disclosed
US-9682043-B2 Method of preparation of mixed phase co-crystals with active agents MEDCRYSTALFORMS, LLC (US) 2017-06-20 — — US disclosed
US-20170079920-A1 Technology for the Preparation of Microparticles NEXBIO, INC. 2017-03-23 — — US disclosed
US-20160331762-A1 TRANSDERMAL TESTOSTERONE DEVICE AND DELIVERY NOVEN PHARMACEUTICALS, INC. (US) 2016-11-17 — — US disclosed
US-20160235675-A1 Technology for the Preparation of Microparticles NEXBIO, INC. 2016-08-18 — — US disclosed
US-20160175436-A1 COMPOSITIONS AND METHODS FOR MUCOSITIS AND ONCOLOGY THERAPIES VICUS THERAPEUTICS LLC (US) 2016-06-23 — — US disclosed
US-20160158198-A1 COMPOSITIONS AND METHODS FOR AMELIORATING CACHEXIA VICUS THERAPEUTICS LLC (US) 2016-06-09 — — US disclosed
EP-3028743-A2 COMPOSITIONS FOR MUCOSITIS AND ONCOLOGY THERAPIES Vicus Therapeutics, LLC (US) 2016-06-08 — — EP disclosed
US-20160129018-A1 COMPOSITIONS AND METHODS FOR MUCOSITIS AND ONCOLOGY THERAPIES VICUS THERAPEUTICS LLC (US) 2016-05-12 — — US disclosed
US-9320742-B2 Transdermal testosterone device and delivery NOVEN PHARMACEUTICALS, INC. (US) 2016-04-26 — — US disclosed
US-20160022820-A1 TRANSDERMAL DELIVERY SYSTEM ACRUX DDS PTY LTD. (AU) 2016-01-28 — — US disclosed
US-20160008376-A1 Compositions, Methods and Uses for Treating Gender-Biased Immune Disorders BIOCOPEA LIMITED (GB) 2016-01-14 — — US disclosed
WO-2016005599-A1 COMPOSITIONS, METHODS AND USES FOR TREATING GENDER-BIASED IMMUNE DISORDERS BIOCOPEA LIMITED (GB) 2016-01-14 — — WO disclosed
US-20150359746-A1 Technology for the Preparation of Microparticles NEXBIO, INC. 2015-12-17 — — US disclosed
US-20150290134-A1 TECHNOLOGY FOR PREPARATION OF MACROMOLECULAR MICROSPHERES NEXBIO, INC. 2015-10-15 — — US disclosed
US-9078810-B2 Transdermal delivery system ACRUX DDS PTY LTD (AU) 2015-07-14 — — US disclosed
CN-104758253-A Technology for preparation of macromolecular microspheres NEXBIO INC 2015-07-08 — — CN disclosed
US-20150050713-A1 Technology for the Preparation of Microparticles NEXBIO, INC. 2015-02-19 — — US disclosed
US-8882729-B2 Transdermal therapeutic system having stabilized membrane LTS LOHMANN THERAPIE SYSTEME AG (DE) 2014-11-11 — — US disclosed
US-8784893-B2 Polymer formulations for delivery of bioactive agents CARBYLAN THERAPEUTICS, INC. (US) 2014-07-22 — — US disclosed
US-20140134150-A1 TECHNOLOGY FOR PREPARATION OF MACROMOLECULAR MICROSPHERES ANSUN BIOPHARMA, INC. (US) 2014-05-15 — — US disclosed
CN-103784408-A Technology for the preparation of microparticles ANSUN BIOPHARMA INC 2014-05-14 — — CN disclosed
US-20140099696-A1 Technology for the Preparation of Microparticles ANSUN BIOPHARMA, INC. (US) 2014-04-10 — — US disclosed
US-20140018435-A1 Transdermal Delivery of Therapeutic Agents Using Poly (Amidoamine) Dendrimers UNIV ILLINOIS CHICAGO (US) 2014-01-16 — — US disclosed
US-8623419-B2 Technology for preparation of macromolecular microspheres ANSUN BIOPHARMA, INC. (US) 2014-01-07 — — US disclosed
US-20130317122-A1 TRANSDERMAL DELIVERY SYSTEM ACRUX DDS PTY LTD. (AU) 2013-11-28 — — US disclosed
US-20130317462-A1 TRANSDERMAL DELIVERY SYSTEM FOR HORMONES AND STEROIDS ACRUX DDS PTY LTD. (AU) 2013-11-28 — — US disclosed
CN-101883556-B Transdermal delivery system for hormones and steroids ACRUX DDS PTY LTD 2013-05-29 — — CN disclosed
US-8414914-B2 Compositions for mucosal delivery of agents VIRUN, INC. (US) 2013-04-09 — — US disclosed
CN-101888830-B Transdermal delivery system ACRUX DDS PTY LTD 2013-01-23 — — CN disclosed
US-20120308644-A1 Compositions for mucosal delivery of agents ARCHIMEDES LABORATORIES, INC. 2012-12-06 — — US disclosed
EP-2506838-A1 TRANSDERMAL TESTOSTERONE DEVICE AND DELIVERY Noven Pharmaceuticals, INC. (US) 2012-10-10 — — EP disclosed
US-20120245537-A1 TRANSDERMAL THERAPEUTIC SYSTEM HAVING STABILIZED MEMBRANE LTS LOHMANN THERAPIE-SYSTEME AG (DE) 2012-09-27 — — US disclosed
US-8252323-B2 Compositions for mucosal delivery of agents VIRUN, INC. (US) 2012-08-28 — — US disclosed
EP-1768647-B1 COMPOSITIONS COMPRISING A MUCOADHESIVE PROTEIN AND AN ACTIVE PRINCIPLE FOR MUCOSAL DELIVERY OF SAID AGENT VIRUN INC (US) 2012-08-08 — — EP disclosed
US-20120141590-A1 Technology for the Preparation of Microparticles MALAKHOV MICHAEL (US) 2012-06-07 — — US disclosed
US-20120116062-A1 TECHNOLOGY FOR PREPARATION OF MACROMOLECULAR MICROSPHERES ANSUN BIOPHARMA, INC. 2012-05-10 — — US disclosed
US-8110565-B2 Of the ACE inhibitor ramipril; controlling the melting point by mixing with the free acid with the ramipril ethyl or methyl ester prodrug and a pressure sensitive adhesive carrier; improved pharmacokinetics; sustained release NOVEN PHARMACEUTICALS, INC. (US) 2012-02-07 — — US disclosed
CN-101005828-B Compositions comprising a mucoadhesive protein and an active principle for mucosal delivery of said agents VIRUN INC 2012-01-11 — — CN disclosed
EP-2374458-A1 Combination of an ACE inhibitor and an NSAID for use in ameliorating cachexia/SIRS Vicus Therapeutics SPE 1, LLC (US) 2011-10-12 — — EP disclosed
EP-2374508-A1 Combination of angiotension receptor blockers (ARB) and NSAIDs for use in ameliorating cachexia Vicus Therapeutics SPE 1, LLC (US) 2011-10-12 — — EP disclosed
EP-1406633-B1 ENHANCED DRUG DELIVERY IN TRANSDERMAL SYSTEMS NOVEN PHARMA (US) 2011-10-05 — — EP disclosed
US-8025898-B2 Of the ACE inhibitor ramipril by mixing with the ramipril (m)ethyl ester prodrug and a pressure sensitive adhesive carrier; improved pharmacokinetics; sustained release NOVEN PHARMACEUTICALS, INC. (US) 2011-09-27 — — US disclosed
US-20110158983-A1 COMPOSITIONS AND METHODS FOR MUCOSITIS AND ONCOLOGY THERAPIES VICUS THERAPEUTICS, LLC 2011-06-30 — — US disclosed
WO-2011068722-A1 TRANSDERMAL TESTOSTERONE DEVICE AND DELIVERY NOVEN PHARMACEUTICALS, INC. (US) 2011-06-09 — — WO disclosed
US-20110129535-A1 TRANSDERMAL TESTOSTERONE DEVICE AND DELIVERY NOVEN PHARMACEUTICALS, INC. 2011-06-02 — — US disclosed
US-20110117184-A1 Compositions for mucosal delivery of agents VIRUN, INC. 2011-05-19 — — US disclosed
US-7906140-B2 Compositions for mucosal delivery of agents VIRUN, INC. (US) 2011-03-15 — — US disclosed
US-20110033540-A1 POLYMER FORMULATIONS FOR DELIVERY OF BIOACTIVE AGENTS CARBYLAN THERAPEUTICS, INC. 2011-02-10 — — US disclosed
CN-101969937-A Transdermal therapeutic system having stabilized membrane LOHMANN THERAPIE SYST LTS 2011-02-09 — — CN disclosed
US-7879831-B2 Steroid on carrier containing pressure sensitive adhesive NOVEN PHARMACEUTICALS, INC. (US) 2011-02-01 — — US disclosed
US-7867986-B2 Enhanced drug delivery in transdermal systems NOVEN PHARMACEUTICALS, INC. (US) 2011-01-11 — — US disclosed
EP-2259844-A1 COMPOSITIONS AND METHODS FOR MUCOSITIS AND ONCOLOGY THERAPIES Vicus Therapeutics SPE 1, LLC (US) 2010-12-15 — — EP disclosed
US-7846916-B2 Enhanced drug delivery in transdermal systems Noven Pharamaceticals, Inc. (US) 2010-12-07 — — US disclosed
US-20100297032-A1 TRANSDERMAL DELIVERY SYSTEM ACRUX DDS PTY LTD. 2010-11-25 — — US disclosed
CN-101888830-A Transdermal delivery system ACRUX DDS PTY LTD 2010-11-17 — — CN disclosed
CN-101883556-A Transdermal delivery system for hormones and steroids ACRUX DDS PTY LTD 2010-11-10 — — CN disclosed
US-20100279988-A1 TRANSDERMAL DELIVERY SYSTEM FOR HORMONES AND STEROIDS ACRUX DDS PTY LTD. 2010-11-04 — — US disclosed
CN-101848704-A Techniques for preparing microparticles NEXBIO INC 2010-09-29 — — CN disclosed
EP-2219603-A1 TRANSDERMAL DELIVERY SYSTEM Acrux DDS Pty Ltd (AU) 2010-08-25 — — EP disclosed
EP-2214643-A1 TRANSDERMAL DELIVERY SYSTEM FOR HORMONES AND STEROIDS Acrux DDS Pty Ltd (AU) 2010-08-11 — — EP disclosed
US-20100166874-A1 Technology for Preparation of Macromolecular Microspheres NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-07-01 — — US disclosed
EP-2173327-A2 TECHNOLOGY FOR THE PREPARATION OF MICROPARTICLES Nexbio, Inc. (US) 2010-04-14 — — EP disclosed
CN-101677957-A Polymer formulations for delivery of bioactive agents CARBYLAN BIOSURGERY INC 2010-03-24 — — CN disclosed
EP-2117513-A2 POLYMER FORMULATIONS FOR DELIVERY OF BIOACTIVE AGENTS Carbylan Biosurgery, Inc. (US) 2009-11-18 — — EP disclosed
WO-2009111648-A1 COMPOSITIONS AND METHODS FOR MUCOSITIS AND ONCOLOGY THERAPIES VICUS THERAPEUTICS, LLC (US) 2009-09-11 — — WO disclosed
US-20090215852-A1 COMPOSITIONS AND METHODS FOR AMELIORATING CACHEXIA CHROMA GROUP, INC. 2009-08-27 — — US disclosed
WO-2009055860-A1 TRANSDERMAL DELIVERY SYSTEM ACRUX DDS PTY LTD (AU) 2009-05-07 — — WO disclosed
US-20090117197-A1 COMPOSITIONS AND METHODS FOR AMELIORATING CACHEXIA VICUS THERAPEUTICS LLC (US) 2009-05-07 — — US disclosed
WO-2009055859-A1 TRANSDERMAL DELIVERY SYSTEM FOR HORMONES AND STEROIDS ACRUX DDS PTY LTD (AU) 2009-05-07 — — WO disclosed
EP-2054052-A1 DRUG COMBINATION PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USING THEM Vicus Therapeutics SPE 1, LLC (US) 2009-05-06 — — EP disclosed
US-20090098207-A1 Technology for the Preparation of Microparticles NEXBIO, INC. (US) 2009-04-16 — — US disclosed
CN-101404980-A Preparation Technology of Macromolecular Microspheres NEXBIO INC (US) 2009-04-08 — — CN disclosed
WO-2009015286-A2 TECHNOLOGY FOR THE PREPARATION OF MICROPARTICLES NEXBIO, INC. (US) 2009-01-29 — — WO disclosed
US-7456159-B2 Enhanced drug delivery in transdermal systems NOVEN PHARMACEUTICALS, INC. (US) 2008-11-25 — — US disclosed
EP-1990049-A2 Combination therapy of beta-blockers and non-steroidal anti-inflammatory drugs (NSAID) Vicus Therapeutics SPE 1, LLC (US) 2008-11-12 — — EP disclosed
EP-1981483-A1 TECHNOLOGY FOR PREPARATION OF MACROMOLECULAR MICROSPHERES Nexbio, Inc. (US) 2008-10-22 — — EP disclosed
WO-2008098019-A2 POLYMER FORMULATIONS FOR DELIVERY OF BIOACTIVE AGENTS CARBYLAN BIOSURGERY, INC. (US) 2008-08-14 — — WO disclosed
US-7404965-B2 Composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels ANTARES PHARMA IPL AG (CH) 2008-07-29 — — US disclosed
US-20080167280-A1 Enhanced drug delivery in transdermal systems NOVEN PHARMACEUTICALS, INC. 2008-07-10 — — US disclosed
US-20080167365-A1 Enhanced drug delivery in transdermal systems NOVEN PHARMACEUTICALS, INC. 2008-07-10 — — US disclosed
EP-1865779-A4 COMPOSITIONS AND METHODS FOR AMELIORATING CACHEXIA VICUS THERAPEUTICS SPE 1 LLC (US) 2008-06-04 — — EP disclosed
CN-100391462-C Enhanced drug delivery in transdermal systems NOVEN PHARMA (US) 2008-06-04 — — CN disclosed
US-7335379-B2 Transdermal pharmaceutical formulation for minimizing skin residues ANTARES PHARMA IPL AG (CH) 2008-02-26 — — US disclosed
US-20080033027-A1 Drug combination pharmaceutical compositions and methods for using them VICUS THERAPEUTICS SPE 1, LLC (US) 2008-02-07 — — US disclosed
WO-2008014471-A1 DRUG COMBINATION PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USING THEM VICUS THERAPEUTICS SPE 1, LLC (US) 2008-01-31 — — WO disclosed
EP-1865779-A2 COMPOSITIONS AND METHODS FOR AMELIORATING CACHEXIA Vicus Therapeutics SPE 1, LLC (US) 2007-12-19 — — EP disclosed
WO-2007114881-A1 TECHNOLOGY FOR PREPARATION OF MACROMOLECULAR MICROSPHERES NEXBIO, INC. (US) 2007-10-11 — — WO disclosed
US-20070190163-A1 Technology for preparation of macromolecular microspheres THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTE OF HEALTH 2007-08-16 — — US disclosed
CN-101005828-A Compositions comprising a mucoadhesive protein and an activeprinciple for mucosal delivery of said agents VIRUN INC (US) 2007-07-25 — — CN disclosed
US-7214381-B2 Composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels ANTARES PHARMA IPL AG (CH) 2007-05-08 — — US disclosed
US-20070098775-A1 Novel composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels ANTARES PHARMA IPL AG 2007-05-03 — — US disclosed
EP-1768647-A1 COMPOSITIONS COMPRISING A MUCOADHESIVE PROTEIN AND AN ACTIVE PRINCIPLE FOR MUCOSAL DELIVERY OF SAID AGENT Virun, Inc. (US) 2007-04-04 — — EP disclosed
EP-1307232-B1 NOVEL COMPOSITION FOR TRANSDERMAL AND/OR TRANSMUCOSAL ADMINISTRATION OF ACTIVE COMPOUNDS THAT ENSURES ADEQUATE THERAPEUTIC LEVELS ANTARES PHARMA IPL AG (CH) 2007-03-07 — — EP disclosed
EP-1727520-A2 METHOD OF PREPARATION OF MIXED PHASE CO-CRYSTALS WITH ACTIVE AGENTS MEDCRYSTALFORMS, LLC (US) 2006-12-06 — — EP disclosed
US-7122198-B1 Fast dissolving composition with prolonged sweet taste PANACEA BIOTEC LIMITED (IN) 2006-10-17 — — US disclosed
WO-2006102476-A2 COMPOSITIONS AND METHODS FOR AMELIORATING CACHEXIA VICUS THERAPEUTICS SPE 1, LLC (US) 2006-09-28 — — WO disclosed
EP-1406633-A4 ENHANCED DRUG DELIVERY IN TRANSDERMAL SYSTEMS NOVEN PHARMA (US) 2006-08-16 — — EP disclosed
US-20060153905-A1 Transdermal pharmaceutical formulation for minimizing skin residues ANTARES PHARMA, INC. 2006-07-13 — — US disclosed
EP-1670433-A1 TRANSDERMAL PHARMACEUTICAL FORMULATION FOR MINIMIZING SKIN RESIDUES Antares Pharma IPL AG (CH) 2006-06-21 — — EP disclosed
US-7026360-B1 Pharmaceutical compositions containing compounds with activity for the enhancement of absorption of active ingredients INPHARMA S.A. (CH) 2006-04-11 — — US disclosed
CN-1239153-C Transdermal therapeutic system based on polyacrylate-contact-bonding adhesives without functional groups LOHMANN THERAPIE SYST LTS (DE) 2006-02-01 — — CN disclosed
WO-2006009825-A1 COMPOSITIONS COMPRISING A MUCOADHESIVE PROTEIN AND AN ACTIVE PRINCIPLE FOR MUCOSAL DELIVERY OF SAID AGENTS VIRUN, INC. (US) 2006-01-26 — — WO disclosed
EP-1021204-B1 BIOADHESIVE COMPOSITIONS AND METHODS FOR TOPICAL ADMINISTRATION OF ACTIVE AGENTS NOVEN PHARMA (US) 2005-12-28 — — EP disclosed
US-20050281772-A1 Compositions for mucosal delivery of agents VIRUN, INC. 2005-12-22 — — US disclosed
US-20050181041-A1 Method of preparation of mixed phase co-crystals with active agents MEDCRYSTALFORMS, LLC (US) 2005-08-18 — — US disclosed
WO-2005055983-A2 METHOD OF PREPARATION OF MIXED PHASE CO-CRYSTALS WITH ACTIVE AGENTS MEDCRYSTALFORMS, LLC (US) 2005-06-23 — — WO disclosed
WO-2005039531-A1 TRANSDERMAL PHARMACEUTICAL FORMULATION FOR MINIMIZING SKIN RESIDUES ANTARES PHARMA IPL AG (CH) 2005-05-06 — — WO disclosed
EP-0801561-B1 COMPOSITION AND METHODS FOR TRANSDERMAL DELIVERY OF ACID-LABILE DRUGS NOVEN PHARMA (US) 2005-04-06 — — EP disclosed
CN-1178699-C Pharmaceutical Compsns. contg. compounds with activity for enhancement of absorption of active ingredients — 2004-12-08 — — CN disclosed
US-20040241219-A1 Transdermal therapeutic system based on polyacrylate-contact-bonding adhesives without functional groups LTS LOHMANN THERAPIE-SYSTEME AG (DE) 2004-12-02 — — US disclosed
US-20040235808-A1 Androstanes as androgen receptor modulators WANG JIABING (US) 2004-11-25 — — US disclosed
CN-1545408-A Transdermal therapeutic system based on polyacrylate adhesive patches without functional groups LTS��������ϵͳ�ɷݹ�˾ 2004-11-10 — — CN disclosed
CN-1543349-A Enhanced drug delivery in transdermal systems ŵ��ҩƷ��˾ 2004-11-03 — — CN disclosed
EP-1429779-A2 ANDROSTANES AS ANDROGEN RECEPTOR MODULATORS Merck & Co., Inc. (US) 2004-06-23 — — EP disclosed
EP-1406633-A1 ENHANCED DRUG DELIVERY IN TRANSDERMAL SYSTEMS NOVEN PHARMACEUTICALS, INC. (US) 2004-04-14 — — EP disclosed
US-20040018241-A1 Bioadhesive compositions and methods for topical administration of active agents NOVEN PHARMACEUTICALS, INC. 2004-01-29 — — US disclosed
US-20030232073-A1 Enhanced drug delivery in transdermal systems NOVEN PHARMACEUTICALS, INC. 2003-12-18 — — US disclosed
US-20030199426-A1 Novel composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels ANTARES PHARMA, INC. 2003-10-23 — — US disclosed
US-20030152615-A1 Enhanced drug delivery in transdermal systems NOVEN PHARMACEUTICALS, INC. 2003-08-14 — — US disclosed
US-20030152613-A1 Enhanced drug delivery in transdermal systems NOVEN PHARMACEUTICALS, INC. 2003-08-14 — — US disclosed
US-20030152614-A1 Enhanced drug delivery in transdermal systems NOVEN PHARMACEUTICALS, INC. 2003-08-14 — — US disclosed
EP-1325752-A2 Composition for transdermal and/or transmucosal administration of active compounds which ensures adequate therapeutic levels Antares Pharma IPL AG (CH) 2003-07-09 — — EP disclosed
EP-1323430-A2 Composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels Antares Pharma IPL AG (CH) 2003-07-02 — — EP disclosed
EP-1323431-A2 Composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels Antares Pharma IPL AG (CH) 2003-07-02 — — EP disclosed
US-6562363-B1 Bioadhesive compositions and methods for topical administration of active agents NOVEN PHARMACEUTICALS, INC. 2003-05-13 — — US disclosed
EP-1307232-A1 NOVEL COMPOSITION FOR TRANSDERMAL AND/OR TRANSMUCOSAL ADMINISTRATION OF ACTIVE COMPOUNDS THAT ENSURES ADEQUATE THERAPEUTIC LEVELS Antares Pharma IPL AG (CH) 2003-05-07 — — EP disclosed
WO-2003026568-A2 ANDROSTANES AS ANDROGEN RECEPTOR MODULATORS MERCK & CO., INC. (US) 2003-04-03 — — WO disclosed
WO-2002102390-A1 ENHANCED DRUG DELIVERY IN TRANSDERMAL SYSTEMS NOVEN PHARMACEUTICALS, INC. (US) 2002-12-27 — — WO disclosed
WO-2002011768-A1 NOVEL COMPOSITION FOR TRANSDERMAL AND/OR TRANSMUCOSAL ADMINISTRATION OF ACTIVE COMPOUNDS THAT ENSURES ADEQUATE THERAPEUTIC LEVELS ANTARES PHARMA IPL AG (CH) 2002-02-14 — — WO disclosed
US-6254558-B1 Method for producing a therapeutic system in the form of plaster LTS LOHMANN THERAPIE-SYSTEME AG (DE) 2001-07-03 — — US disclosed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 — — CN disclosed
US-6221383-B1 BLEND OF AT LEAST TWO POLYMERS, OR AT LEAST ONE POLYMER AND A SOLUBLE POLYVINYLPYRROLIDONE, IN COMBINATION WITH A DRUG PROVIDES A PRESSURE-SENSITIVE ADHESIVE COMPOSITION FOR A TRANSDERMAL DRUG DELIVERY SYSTEM NOVEN PHARMACEUTICALS, INC. 2001-04-24 — — US disclosed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 — — EP disclosed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 — — WO disclosed
EP-1021204-A2 BIOADHESIVE COMPOSITIONS AND METHODS FOR TOPICAL ADMINISTRATION OF ACTIVE AGENTS NOVEN PHARMACEUTICALS, INC. (US) 2000-07-26 — — EP disclosed
US-6024976-A TRANSDERMAL DRUG DELIVERY WITH PRESSURE SENSITIVE ADHESIVE COMPOSITION OF POLYVINYLPYRROLIDONE WITH DRUG IN MULTILAYER PATCH NOVEN PHARMACEUTICALS, INC. (US) 2000-02-15 — — US disclosed
US-6024974-A TRANSDERMAL DRUG DELIVERY NOVEN PHARMACEUTICALS, INC. (US) 2000-02-15 — — US disclosed
WO-1999015210-A2 BIOADHESIVE COMPOSITIONS AND METHODS FOR TOPICAL ADMINISTRATION OF ACTIVE AGENTS NOVEN PHARMACEUTICALS, INC. (US) 1999-04-01 — — WO disclosed
WO-1998053863-A2 COMPOSITION AND METHODS FOR TRANSDERMAL DELIVERY OF ACID LABILE DRUGS NOVEN PHARMACEUTICALS, INC. (US) 1998-12-03 — — WO disclosed
US-5798338-A STEROID/BETA-CYCLODEXTRIN CLATHRATE; OXIDATION RESISTANCE SCHERING AKTIENGESELLSCHAFT (DE) 1998-08-25 — — US disclosed
US-5719197-A DRUG DELIVERY NOVEN PHARMACEUTICALS, INC. (US) 1998-02-17 — — US disclosed
EP-0801561-A2 COMPOSITION AND METHODS FOR TRANSDERMAL DELIVERY OF ACID-LABILE DRUGS NOVEN PHARMACEUTICALS, INC. (US) 1997-10-22 — — EP disclosed
US-5656286-A BLEND OF TWO POLYMERS; PRESSURE SENSITIVE ADHESIVE NOVEN PHARMACEUTICALS, INC. (US) 1997-08-12 — — US disclosed
WO-1996040084-A1 COMPOSITIONS AND METHODS FOR USE OF PRESSURE SENSITIVE ADHESIVE TRANSDERMAL DEVICES CONTAINING A BIOADHESIVE HUMECTANT NOVEN PHARMACEUTICALS, INC. (US) 1996-12-19 — — WO disclosed
WO-1996040086-A2 COMPOSITIONS AND METHODS FOR TOPICAL ADMINISTRATION OF PHARMACEUTICALLY ACTIVE AGENTS NOVEN PHARMACEUTICALS, INC. (US) 1996-12-19 — — WO disclosed
WO-1996020699-A1 COMPOSITION AND METHODS FOR TRANSDERMAL DELIVERY OF ACID-LABILE DRUGS NOVEN PHARMACEUTICALS, INC. (US) 1996-07-11 — — WO disclosed
US-5525727-A ANALGESIC OR NARCOTIC ANTAGONIST UNIVERSITY OF FLORIDA (US) 1996-06-11 — — US disclosed
US-5446070-A Flexible, finite, bioadhesive, therapeutical agent in solid form NOVER PHARMACEUTICALS, INC. (US) 1995-08-29 — — US disclosed
US-5187158-A Sustained delivery of viricides UNIVERSITY OF FLORIDA (US) 1993-02-16 — — US disclosed
US-5008257-A Penicillin or cephalosporin antibiotics UNIVERSITY OF FLORIDA (US) 1991-04-16 — — US disclosed
US-4900837-A Brain-specific drug delivery of steroid sex hormones cleaved from pyridinium carboxylates and dihydro-pyridine carboxylate precursors UNIVERSITY OF FLORIDA (US) 1990-02-13 — — US disclosed
US-4880921-A Brain-specific drug delivery UNIVERSITY OF FLORIDA (US) 1989-11-14 — — US disclosed
US-4824850-A DIHYDROPYRIDINE-PYRIDINIUM SALT REDOX CARRIER UNIVERSITY OF FLORIDA (US) 1989-04-25 — — US disclosed
US-4622218-A Testicular-specific drug delivery UNIVERSITY OF FLORIDA (US) 1986-11-11 — — US disclosed
US-4540564-A DIHYDROPYRIDINE AND/OR PYRIDINIUM SALT REDOX CARRIER UNIVERSITY OF FLORIDA (US) 1985-09-10 — — US disclosed
US-4479932-A DIHYDROPYRIDINE PYRIDINIUM SALT REDOX CARRIER UNIVERSITY OF FLORIDA (US) 1984-10-30 — — US disclosed
EP-0110955-A1 BRAIN-SPECIFIC DRUG DELIVERY. UNIV FLORIDA (US) 1984-06-20 — — EP disclosed
WO-1983003968-A1 BRAIN-SPECIFIC DRUG DELIVERY UNIVERSITY OF FLORIDA (US) 1983-11-24 — — WO disclosed
WO-1983003968-A1 BRAIN-SPECIFIC DRUG DELIVERY UNIVERSITY OF FLORIDA (US) 1983-11-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100279988-A1 TRANSDERMAL DELIVERY SYSTEM FOR HORMONES AND STEROIDS SHBG, PGR, NR5A1 CYP3A4 405/4885LMNA 3386/4885TSHR 85/4885
US-20220079955-A1 Testosterone Ester Triglyceride Formulations SHBG, NR5A1, HSD17B11 CYP3A4 118/4885LMNA 498/4885TSHR 770/4885
US-20250032509-A1 Testosterone Ester Triglyceride Formulations SHBG, NR5A1, HSD17B11 CYP3A4 118/4885LMNA 498/4885TSHR 770/4885
US-20100297032-A1 TRANSDERMAL DELIVERY SYSTEM S100A10, MMP20, TLR6 CYP3A4 933/4885LMNA 3672/4885TSHR 1688/4885
US-20260014080-A1 LIPOSOMAL PREPARATION WITH ENCAPSULATED HORMONES, METHOD OF PRODUCTION AND USE THEREOF NR5A1, SHBG, GNRHR CYP3A4 1458/4885LMNA 796/4885TSHR 232/4885
US-10646495-B2 Testosterone ester triglyceride formulations SHBG, NR5A1, HSD17B11 CYP3A4 118/4885LMNA 498/4885TSHR 770/4885
US-20160022820-A1 TRANSDERMAL DELIVERY SYSTEM S100A10, MMP20, TLR6 CYP3A4 933/4885LMNA 3672/4885TSHR 1688/4885
US-20130317122-A1 TRANSDERMAL DELIVERY SYSTEM S100A10, MMP20, TLR6 CYP3A4 933/4885LMNA 3672/4885TSHR 1688/4885
US-12144817-B2 Testosterone ester triglyceride formulations SHBG, NR5A1, HSD17B11 CYP3A4 118/4885LMNA 498/4885TSHR 770/4885
US-11123352-B2 Testosterone ester triglyceride formulations SHBG, NR5A1, HSD17B11 CYP3A4 118/4885LMNA 498/4885TSHR 770/4885
US-20200289528-A1 Testosterone Ester Triglyceride Formulations SHBG, NR5A1, HSD17B11 CYP3A4 118/4885LMNA 498/4885TSHR 770/4885
US-20110033540-A1 POLYMER FORMULATIONS FOR DELIVERY OF BIOACTIVE AGENTS BMP2, BMP6, BMP4 CYP3A4 4757/4885LMNA 1101/4885TSHR 4548/4885
US-20130317462-A1 TRANSDERMAL DELIVERY SYSTEM FOR HORMONES AND STEROIDS SHBG, PGR, NR5A1 CYP3A4 405/4885LMNA 3386/4885TSHR 85/4885
US-20040235808-A1 Androstanes as androgen receptor modulators SHBG, FSHR, AR CYP3A4 695/4885LMNA 3934/4885TSHR 231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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