SCHEMBL548209

SCHEMBL548209

C=CC(F)OC(=O)C(=C)C#N

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27568889 0.79
SCHEMBL11500858 0.78 ALDH1A1 (0.42) ALDH1A1TSHR
SCHEMBL25432688 0.77 ALDH1A1 (0.46) ALDH1A1TSHR
SCHEMBL4826933 0.76 ALDH1A1 (0.44) ALDH1A1TSHR
SCHEMBL5404495 0.76 TSHR (0.48) ALDH1A1TSHR
SCHEMBL5477386 0.76 ALDH1A1 (0.40) ALDH1A1TSHR
SCHEMBL8673134 0.75
SCHEMBL2529839 0.74 ALDH1A1 (0.43) ALDH1A1TSHR
SCHEMBL87373 0.74 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL10825733 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9839717-B2 Cyanoacrylate adhesive composition and method for making the same CHU FA-TER (TW) 2017-12-12 US claimed
US-9657205-B2 Adhesive beads Dry, Carolyn (US) 2017-05-23 US claimed
US-20170072092-A1 CYANOACRYLATE ADHESIVE COMPOSITION AND METHOD FOR MAKING THE SAME CHU FA-TER (TW) 2017-03-16 US claimed
US-20150361314-A1 ADHESIVE BEADS DRY CAROLYN M (US) 2015-12-17 US claimed
EP-2951256-A1 ADHESIVE BEADS Dry, Carolyn M. (US) 2015-12-09 EP claimed
CN-104888268-A Cyanoacrylate adhesive and its preparation method GENEJET BIOTECH CO LTD 2015-09-09 CN claimed
US-8877309-B1 Self-repairing inflatable articles DRY CAROLYN M (US) 2014-11-04 US claimed
WO-2014121223-A1 ADHESIVE BEADS DRY CAROLYN M (US) 2014-08-07 WO claimed
US-20100213096-A1 Cyanoacrylate Adhesive Compositions and Devices and Process for Sterilization Thereof CLAST TRADING LIMITED (CN) 2010-08-26 US claimed
EP-1807121-A4 PROCESS FOR STERILIZATION OF AND CYANOACRYLATE ADHESIVE COMPOSITIONS AND DEVICES CHEMENCE INC (US) 2009-04-01 EP claimed
US-20060115445-A1 Compositions for treating keratin materials comprising electrophilic monomers and liquid crystal agents L'OREAL S.A. (FR) 2006-06-01 US claimed
US-20060110334-A1 Two-compartment aerosol device comprising electrophilic monomers, and use thereof for the cosmetic treatment of the hair L'OREAL S.A. (FR) 2006-05-25 US claimed
US-20060088493-A1 Composition and process for the cosmetic treatment of keratin materials based on electrophilic monomers and non-silicone polymers L'OREAL S.A. (FR) 2006-04-27 US claimed
US-20060083706-A1 Haircare composition comprising at least one electrophilic monomer and micro- or nanoparticles of at least one solid lubricant L'OREAL S.A. (FR) 2006-04-20 US claimed
US-20060080792-A1 Film-forming composition for the cosmetic treatment of keratin materials comprising at least one electrophilic monomer and at least one non-silicone polymer L'OREAL S.A. (FR) 2006-04-20 US claimed
US-20060083762-A1 Uses of compositions comprising electrophilic monomers and micro-particles or nanoparticles L'OREAL S.A. (FR) 2006-04-20 US claimed
US-20060078523-A1 Composition comprising at least one electrophilic monomer and at least one acid in a cosmetically acceptable anhydrous medium, and use thereof for cosmetic treatment of the hair L'OREAL S.A. (FR) 2006-04-13 US claimed
US-20060078522-A1 Composition for treating keratin materials comprising at least one electrophilic monomer and at least one salt L'OREAL S.A. (FR) 2006-04-13 US claimed
WO-2006034064-A2 PROCESS FOR STERILIZATION OF AND CYANOACRYLATE ADHESIVE COMPOSITIONS AND DEVICES CHEMENCE INC (US) 2006-03-30 WO claimed
US-20060062687-A1 Process for sterilization of and cyanoacrylate adhesives compositions and devices CLAST TRADING LTD (HK) 2006-03-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060110334-A1 Two-compartment aerosol device comprising electrophilic monomers, and use thereof for the cosmetic treatment of the hair POLR1C, TRPA1, GSTM2 ALDH1A1 492/4885TSHR 4318/4885
US-20060088493-A1 Composition and process for the cosmetic treatment of keratin materials based on electrophilic monomers and non-silicone polymers KRT18, CUTA, MARK1 ALDH1A1 3552/4885TSHR 4581/4885
US-20060083762-A1 Uses of compositions comprising electrophilic monomers and micro-particles or nanoparticles KRT18, PRKDC, ACP1 ALDH1A1 828/4885TSHR 4297/4885
US-20060115445-A1 Compositions for treating keratin materials comprising electrophilic monomers and liquid crystal agents KRT18, PRKDC, CUTA ALDH1A1 1395/4885TSHR 4246/4885
US-20060083706-A1 Haircare composition comprising at least one electrophilic monomer and micro- or nanoparticles of at least one solid lubricant MITF, CUTA, NACA ALDH1A1 43/4885TSHR 3327/4885
US-20060078523-A1 Composition comprising at least one electrophilic monomer and at least one acid in a cosmetically acceptable anhydrous medium, and use thereof for cosmetic treatment of the hair HOGA1, OAT, SUCLG1 ALDH1A1 18/4885TSHR 4459/4885
US-20060078522-A1 Composition for treating keratin materials comprising at least one electrophilic monomer and at least one salt KRT18, DSG1, DSC1 ALDH1A1 1453/4885TSHR 4360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.