Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18796080 | 0.79 | GABRA1 (0.43) | GABRA1GABRB2CA2ALDH1A1TDP1 | |
| SCHEMBL987729 | 0.73 | ACHE (0.43) | CA2ALDH1A1TDP1SMN1; SMN2NPC1 | |
| SCHEMBL5952303 | 0.73 | ENPP2 (0.39) | MAPTCA14CA5ACA4CA5B | |
| SCHEMBL78717 | 0.72 | ALDH1A1 (0.47) | GABRA1GABRB2CA2ALDH1A1TDP1 | |
| SCHEMBL4305951 | 0.72 | GABRA1 (0.35) | GABRA1GABRB2CA2HPGDLMNA | |
| SCHEMBL10340777 | 0.72 | ALDH1A1 (0.47) | GABRA1GABRB2CA2ALDH1A1TDP1 | |
| SCHEMBL2543212 | 0.71 | ALDH1A1 (0.53) | GABRA1GABRB2CA2ALDH1A1TDP1 | |
| SCHEMBL18692002 | 0.70 | ALDH1A1 (0.45) | GABRA1GABRB2CA2ALDH1A1TDP1 | |
| SCHEMBL18796466 | 0.70 | TSHR (0.39) | GABRA1GABRB2CA2ALDH1A1TDP1 | |
| SCHEMBL989253 | 0.70 | TRPA1 (0.39) | CA2ALDH1A1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190127397-A1 | Complexes for Nucleophilic, Radical, and Electrophilic Polyfluoroalkylation | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2019-05-02 | — | — | US | disclosed |
| WO-2017223406-A1 | COMPLEXES FOR NUCLEOPHILIC, RADICAL, AND ELECTROPHILIC POLYFLUOROALKYLATION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-12-28 | — | — | WO | disclosed |
| US-9408926-B2 | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy | BRACCO SUISSE S.A. (CH) | 2016-08-09 | — | — | US | disclosed |
| US-20140161732-A1 | KDR AND VEGF/KDR BINDING PEPTIDES AND THEIR USE IN DIAGNOSIS AND THERAPY | BRACCO SUISSE S.A. (CH) | 2014-06-12 | — | — | US | disclosed |
| EP-1482987-A4 | MULTIVALENT CONSTRUCTS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS | BRACCO INT BV (NL) | 2007-03-07 | — | — | EP | disclosed |
| EP-1482987-A1 | MULTIVALENT CONSTRUCTS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS | BRACCO INTERNATIONAL B.V. (NL) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003084574-A1 | MULTIVALENT CONSTRUCTS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS | BRACCO INTERNATIONAL BV (NL) | 2003-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127397-A1 | Complexes for Nucleophilic, Radical, and Electrophilic Polyfluoroalkylation | NBAS, PFAS, PCBP1 | GABRA1 328/4885GABRB2 387/4885CA2 3218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.