Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Formaldehyde. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 known ✓ | P14867 | 4/20 | 0.46 |
| ▸ | GABRB2 known ✓ | P47870 | 2/20 | 0.46 |
| ▸ | GABRG2 known ✓ | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 known ✓ | P28472 | 2/20 | 0.43 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.43 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.43 |
| ▸ | GABRB1 known ✓ | P18505 | 2/20 | 0.43 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.43 |
| ▸ | GABRA5 known ✓ | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 known ✓ | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 known ✓ | P47869 | 1/20 | 0.43 |
| ▸ | GABRA4 known ✓ | P48169 | 1/20 | 0.43 |
| ▸ | GABRA6 known ✓ | Q16445 | 1/20 | 0.43 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL7031784 | 0.93 | GABRA1 (0.52) | GABRA1GABRB2GABRG2GABRB3LMNA | |
| Formaldehyde SCHEMBL11571228 | 0.93 | GABRA1 (0.52) | GABRA1GABRB2GABRG2GABRB3LMNA | |
| Formaldehyde SCHEMBL27649752 | 0.87 | GABRA1 (0.46) | GABRA1GABRB2GABRG2GABRB3LMNA | |
| Hydrogen Peroxide SCHEMBL7983120 | 0.86 | GABRA1 (0.59) | GABRA1GABRB2GABRG2GABRB3LMNA | |
| Isopropylbenzene SCHEMBL3089101 | 0.81 | CRHBP (0.39) | LMNACA1CA2CYP3A4HPGD | |
| Hydrogen Peroxide SCHEMBL35519 | 0.75 | GABRA1 (0.65) | GABRA1GABRB2GABRG2GABRB3LMNA | |
| Hydrogen Peroxide SCHEMBL99126 | 0.75 | GABRA1 (0.65) | GABRA1GABRB2GABRG2GABRB3LMNA | |
| Hydrogen Peroxide SCHEMBL20593356 | 0.75 | GABRA1 (0.65) | GABRA1GABRB2GABRG2GABRB3LMNA | |
| Hydrogen Peroxide SCHEMBL29394264 | 0.75 | GABRA1 (0.65) | GABRA1GABRB2GABRG2GABRB3LMNA | |
| Hydrogen Peroxide SCHEMBL30120583 | 0.75 | GABRA1 (0.65) | GABRA1GABRB2GABRG2GABRB3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220193983-A1 | ACRYLIC COMPOSITION FOR 3-D PRINTING | ARKEMA FRANCE (FR) | 2022-06-23 | — | — | US | disclosed |
| CN-114375248-A | Acrylic compositions for 3D printing | 阿科玛法国公司 | 2022-04-19 | — | — | CN | disclosed |
| EP-3946784-A1 | ACRYLIC COMPOSITION FOR 3-D PRINTING | ARKEMA FRANCE (FR) | 2022-02-09 | — | — | EP | disclosed |
| EP-1350812-B1 | METHYL METHACRYLATE COPOLYMER BLENDS | ARKEMA FRANCE (FR) | 2017-07-26 | — | — | EP | disclosed |
| CN-100363420-C | Weatherable impact-resisting acrylic compositions | ATOFINA (FR) | 2008-01-23 | — | — | CN | disclosed |
| US-7294399-B2 | Weather-resistant, high-impact strength acrylic compositions | ARKEMA FRANCE (FR) | 2007-11-13 | — | — | US | disclosed |
| US-7195820-B2 | Core-shell polymers having hydrophilic shells for improved shell coverage and anti-blocking properties | ARKEMA INC. (US) | 2007-03-27 | — | — | US | disclosed |
| US-20050154140-A1 | Core-shell polymers having hydrophilic shells for improved shell coverage and anti-blocking properties | ARKEMA INC. | 2005-07-14 | — | — | US | disclosed |
| EP-1541603-A1 | Core-shell polymers having having hydrophilic shells for improved shell coverage and anti-blocking properties | Arkema Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20030216510-A1 | Weather-resistant, high-impact strength acrylic compositions | ALTER DOMUS (US) LLC | 2003-11-20 | — | — | US | disclosed |
| CN-1450117-A | Weatherable impact-resisting acrylic compositions | ATOFINA (FR) | 2003-10-22 | — | — | CN | disclosed |
| EP-1350812-A2 | Methyl methacrylate copolymer blends | ATOFINA CHEMICALS, INC. (US) | 2003-10-08 | — | — | EP | disclosed |
| EP-0003652-B1 | MULTIPLE STAGE SEQUENTIALLY PRODUCED THERMOPLASTIC POLYMERS AND FILMS OF SUCH POLYMERS APPLIED TO A SUBSTRATE | ROHM AND HAAS COMPANY (US) | 1982-09-22 | — | — | EP | disclosed |
| US-4187259-A | Polymer blends with improved hydrolytic stability comprising a linear aromatic polyester and a methacrylate cross-linked acrylate copolymer | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1980-02-05 | — | — | US | disclosed |
| EP-0003652-A1 | Multiple stage sequentially produced thermoplastic polymers and films of such polymers applied to a substrate | ROHM AND HAAS COMPANY (US) | 1979-08-22 | — | — | EP | disclosed |
| US-4141935-A | SHEATH-CORE ACRYLIC GRAFTED POLYMERS | ROHM AND HAAS COMPANY (US) | 1979-02-27 | — | — | US | disclosed |