Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL551858 | 0.87 | ALB (0.47) | POLBCES2CES1KMT2AMEN1 | |
| SCHEMBL550568 | 0.83 | POLB (0.50) | PTPN1POLBCES2CES1KMT2A | |
| SCHEMBL7135256 | 0.83 | ITGB2 (0.53) | CES2CES1KMT2AMEN1HTT | |
| SCHEMBL12877749 | 0.81 | CES2 (0.55) | POLBCES2CES1HTTTP53 | |
| SCHEMBL3377192 | 0.81 | GAA (0.63) | POLBCES2CES1KMT2AMEN1 | |
| SCHEMBL551796 | 0.81 | PBRM1 (0.49) | POLBKMT2AMEN1HTTALDH1A1 | |
| SCHEMBL550367 | 0.81 | ALDH1A1 (0.43) | KMT2AMEN1HTTALDH1A1LMNA | |
| SCHEMBL551897 | 0.81 | ALDH1A1 (0.50) | POLBKMT2AMEN1HTTALDH1A1 | |
| SCHEMBL24571387 | 0.80 | TAS1R3 (0.48) | POLBHTTTP53ALDH1A1LMNA | |
| SCHEMBL6028220 | 0.79 | PTPN1 (0.45) | PTPN1POLBKMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101198589-B | N-benzanilides with insecticidal activity | BAYER CROPSCIENCE AG | 2012-07-18 | — | — | CN | disclosed |
| US-8110689-B2 | Benzanilides with insecticidal activity | BAYER CROPSCIENE AG (DE) | 2012-02-07 | — | — | US | disclosed |
| US-20100130743-A1 | HETEROCYCLE-SUBSTITUTED, N-PHENYL-PHTHALAMIDE DERIVATIVES, RELATED COMPOUNDS AND THEIR USE AS INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2010-05-27 | — | — | US | disclosed |
| US-20100062937-A1 | BENZANILIDES WITH INSECTICIDAL ACTIVITY | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | US | disclosed |
| US-7674807-B2 | Heterocycle-substituted n-phenyl-phthalamide derivatives, related compounds and their use as insecticides | BAYER CROPSCIENCE AG (DE) | 2010-03-09 | — | — | US | disclosed |
| EP-1727804-B1 | N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2009-11-04 | — | — | EP | disclosed |
| CN-100522952-C | Insecticidal phthalamide derivatives | BAYER CROPSCIENCE AG (DE) | 2009-08-05 | — | — | CN | disclosed |
| CN-101198589-A | N-benzanilides with insecticidal activity | BAYER CROPSCIENCE AG (DE) | 2008-06-11 | — | — | CN | disclosed |
| EP-1893567-A1 | BENZANILIDES WITH INSECTICIDAL ACTIVITY | Bayer CropScience AG (DE) | 2008-03-05 | — | — | EP | disclosed |
| US-20070299085-A1 | N1-((Pyrazol-1-Ymethyl)-2-Methylphenyl)-Phatalamide Derivatives And Related Compounds Insecticides | BAYER CROPSCIENCE AG (DE) | 2007-12-27 | — | — | US | disclosed |
| CN-1930129-A | N1- ((pyrazol-1-ylmethyl) -2-methylphenyl) -phthalamide derivative and related compound insecticide | BAYER CROPSCIENCE AG (DE) | 2007-03-14 | — | — | CN | disclosed |
| WO-2006133823-A1 | BENZANILIDES WITH INSECTICIDAL ACTIVITY | BAYER CROPSCIENCE AG (DE) | 2006-12-21 | — | — | WO | disclosed |
| EP-1727804-A1 | N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2006-12-06 | — | — | EP | disclosed |
| US-20060223872-A1 | Insecticidal phthalamide derivatives | BAYER CROPSCIENCE AG (DE) | 2006-10-05 | — | — | US | disclosed |
| CN-1759105-A | Phthalamide derivatives having insecticidal activity | BAYER CROPSCIENCE AG (DE) | 2006-04-12 | — | — | CN | disclosed |
| EP-1606271-A1 | INSECTICIDAL PHTHALAMIDE DERIVATIVES | Bayer CropScience AG (DE) | 2005-12-21 | — | — | EP | disclosed |
| WO-2005095351-A1 | N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2005-10-13 | — | — | WO | disclosed |
| WO-2004080984-A1 | INSECTICIDAL PHTHALAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2004-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100062937-A1 | BENZANILIDES WITH INSECTICIDAL ACTIVITY | CBR3, HCN3, HAX1 | PTPN1 3272/4885POLB 4173/4885CES2 172/4885 |
| US-20100130743-A1 | HETEROCYCLE-SUBSTITUTED, N-PHENYL-PHTHALAMIDE DERIVATIVES, RELATED COMPOUNDS AND THEIR USE AS INSECTICIDES | DDT, SQOR, CYP2S1 | PTPN1 1425/4885POLB 4359/4885CES2 741/4885 |
| US-20060223872-A1 | Insecticidal phthalamide derivatives | CRYAA, PRXL2A, H1-2 | PTPN1 1301/4885POLB 4402/4885CES2 2299/4885 |
| US-20070299085-A1 | N1-((Pyrazol-1-Ymethyl)-2-Methylphenyl)-Phatalamide Derivatives And Related Compounds Insecticides | CHRM1, KCNH1, DDT | PTPN1 1606/4885POLB 4401/4885CES2 270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.