Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | PGR | P06401 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | TGM2 | P21980 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | RNF4 | P78317 | 1/20 | 0.62 |
| ▸ | F13A1 | P00488 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | PNLIP | P16233 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28881974 | 0.85 | HPGD (0.62) | SMN1; SMN2HPGDPGRTGM2RNF4 | |
| SCHEMBL7823002 | 0.85 | PEPD (0.77) | HPGDGAAMAPTGFERHSD17B10 | |
| SCHEMBL30053559 | 0.84 | CA12 (0.73) | SMN1; SMN2HPGDPGRMAPTTGM2 | |
| SCHEMBL4653369 | 0.84 | HPGD (0.70) | SMN1; SMN2HPGDPGRTGM2RNF4 | |
| SCHEMBL4089354 | 0.84 | MITF (0.65) | SMN1; SMN2HPGDGAAMAPTGFER | |
| SCHEMBL4092732 | 0.83 | NPC1 (0.78) | SMN1; SMN2HPGDMAPTHSD17B10ALDH1A1 | |
| SCHEMBL13750226 | 0.83 | KIF11 (0.70) | SMN1; SMN2HPGDGAAHSD17B10ALDH1A1 | |
| SCHEMBL21295380 | 0.82 | CA12 (0.71) | SMN1; SMN2HPGDPGRMAPTTGM2 | |
| SCHEMBL5008975 | 0.81 | HSD17B10 (0.58) | HPGDHSD17B10ALDH1A1NPC1 | |
| SCHEMBL8535350 | 0.81 | CA12 (0.65) | SMN1; SMN2HPGDPGRMAPTTGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111988996-A | Increasing yield of nut bearing plants | UPL有限责任公司 | 2020-11-24 | — | — | CN | claimed |
| US-20190254281-A1 | ENHANCED YIELD IN NUT BEARING PLANTS | UPL CORPORATION LTD. (MU) | 2019-08-22 | — | — | US | claimed |
| WO-2019161274-A1 | ENHANCED YIELD IN NUT BEARING PLANTS | UPL CORPORATION LTD. (MU) | 2019-08-22 | — | — | WO | claimed |
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | claimed |
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | claimed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
| CN-1406110-A | Enhancement of seed/fruit/nut yield from flowering plants | UNIROYAL CHEM CO INC (US) | 2003-03-26 | — | — | CN | claimed |
| WO-2001064036-A1 | ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2001-09-07 | — | — | WO | claimed |
| US-6242385-B1 | SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES | UNIROYAL CHEMICAL COMPANY, INC. | 2001-06-05 | — | — | US | claimed |
| CN-115974768-B | Preparation method and application of piperlonguminine derivatives containing diaryl urea structure | 贵州大学 | 2024-09-27 | — | — | CN | disclosed |
| CN-111819172-B | Triazine derivatives for the treatment of neurotrophin related diseases | 阿泽克制药公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-111988996-B | Improving yield of nut bearing plants | UPL有限责任公司 | 2023-07-14 | — | — | CN | disclosed |
| US-11641859-B2 | Enhanced yield in nut bearing plants | UPL CORPORATION LTD. (MU) | 2023-05-09 | — | — | US | disclosed |
| CN-115974768-A | Preparation method and application of piperlonguminine derivatives containing diaryl urea structure | 贵州大学 | 2023-04-18 | — | — | CN | disclosed |
| US-6242385-B1 | SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES | UNIROYAL CHEMICAL COMPANY, INC. | 2001-06-05 | — | — | US | disclosed |
| CN-1290164-A | Inhibition of RAF kinase with substituted heterocyclic ureas | BAYER AG (US) | 2001-04-04 | — | — | CN | disclosed |
| EP-0777471-A1 | INHIBITION OF LEUKOTRIENE BIOSYNTHESIS WITH UREA DERIVATIVES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996003983-A1 | INHIBITION OF LEUKOTRIENE BIOSYNTHESIS WITH UREA DERIVATIVES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-02-15 | — | — | WO | disclosed |
| CN-1038838-A | POLYETHER ANTIBIOTIC | LILLY CO ELI (US) | 1990-01-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | SMN1; SMN2 3015/4885HPGD 2673/4885PGR 4667/4885 |
| US-20190254281-A1 | ENHANCED YIELD IN NUT BEARING PLANTS | NUTF2, MYCBP, MYCBP2 | SMN1; SMN2 2129/4885HPGD 1641/4885PGR 2698/4885 |
| US-11641859-B2 | Enhanced yield in nut bearing plants | NUTF2, MYCBP, MYCBP2 | SMN1; SMN2 2129/4885HPGD 1641/4885PGR 2698/4885 |
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | SMN1; SMN2 2635/4885HPGD 1253/4885PGR 3743/4885 |
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | SMN1; SMN2 2022/4885HPGD 1657/4885PGR 3560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.