Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | RAC1 | P63000 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5535948 | 0.86 | CCR2 (0.40) | ITGB3ITGA2BSIGMAR1MAPK14DGAT1 | |
| SCHEMBL5533939 | 0.85 | THRB (0.44) | ITGB3ITGA2BSIGMAR1MAPK14MAPT | |
| SCHEMBL5530623 | 0.80 | SIGMAR1 (0.45) | ITGB3ITGA2BSIGMAR1DGAT1 | |
| SCHEMBL7389426 | 0.77 | THRB (0.45) | POLBMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL7380624 | 0.76 | PKM (0.44) | SIGMAR1PIK3CAPOLBMAPTALDH1A1 | |
| SCHEMBL7592402 | 0.76 | MAPT (0.46) | SIGMAR1POLBMAPTTP53MAOA | |
| SCHEMBL7387348 | 0.75 | MAPT (0.49) | SIGMAR1POLBMAPTDGAT1LMNA | |
| SCHEMBL7386967 | 0.75 | MAPT (0.44) | SIGMAR1POLBMAPTTP53DGAT1 | |
| SCHEMBL5530617 | 0.74 | SIGMAR1 (0.45) | ITGB3ITGA2BSIGMAR1DGAT1 | |
| SCHEMBL7387692 | 0.73 | THRB (0.42) | SIGMAR1MAPTALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1416931-B1 | INHIBITORS OF POLYQ-AGGREGATION | MAX PLANCK GESELLSCHAFT (DE) | 2007-06-13 | — | — | EP | claimed |