Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4841791 | 0.78 | HTR2C (0.40) | ALDH1A1KDM4ELMNA | |
| SCHEMBL2745021 | 0.73 | LTA4H (0.38) | CASR | |
| SCHEMBL8796135 | 0.73 | TSHR (0.34) | CASR | |
| SCHEMBL7985829 | 0.73 | ADRB2 (0.34) | — | |
| SCHEMBL8149465 | 0.70 | ADRB1 (0.41) | KDM4ELMNA | |
| SCHEMBL1621418 | 0.69 | FGFR1 (0.32) | — | |
| SCHEMBL5207671 | 0.68 | HTR2A (0.36) | ALDH1A1 | |
| SCHEMBL9347230 | 0.68 | — | — | |
| SCHEMBL8796366 | 0.68 | IDO1 (0.42) | ALDH1A1 | |
| SCHEMBL7791563 | 0.68 | CA2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363874-B1 | TRYPTASE INHIBITORS | ALTANA PHARMA AG (DE) | 2007-06-06 | — | — | EP | disclosed |
| US-7101911-B2 | Tryptase inhibitors | ALTANA PHARMA AG (DE) | 2006-09-05 | — | — | US | disclosed |
| US-20040087791-A1 | Bis(substituted propynyl)-substituted benzenes, pyridines, pyrimidines, pyrazines, pyridines, furans and pyrroles; e.g., 3,5-bis-(3-(4-aminomethylbenzylaminocarbonyloxy)prop-1-ynyl)--1 -hydroxymethylbenzene | ALTANA PHARMA AG (DE) | 2004-05-06 | — | — | US | disclosed |
| EP-1363874-A2 | TRYPTASE INHIBITORS | ALTANA Pharma AG (DE) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002066420-A2 | TRYPTASE INHIBITORS | ALTANA PHARMA AG (DE) | 2002-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087791-A1 | Bis(substituted propynyl)-substituted benzenes, pyridines, pyrimidines, pyrazines, pyridines, furans and pyrroles; e.g., 3,5-bis-(3-(4-aminomethylbenzylaminocarbonyloxy)prop-1-ynyl)--1 -hydroxymethylbenzene | TPSB2, TPSAB1, TPSG1 | ALDH1A1 582/4885KDM4E 550/4885LMNA 1409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.