Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.53 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57091 | 0.98 | MEN1 (0.52) | MEN1KMT2APTGS1PTGS2MAPT | |
| SCHEMBL512447 | 0.89 | PTGS1 (0.65) | MEN1KMT2APTGS1PTGS2MAPT | |
| SCHEMBL7531909 | 0.88 | MEN1 (0.57) | MEN1KMT2APTGS1PTGS2MAPT | |
| SCHEMBL11727137 | 0.87 | ALDH1A1 (0.63) | MEN1KMT2APTGS1PTGS2MAPT | |
| SCHEMBL11726351 | 0.87 | ALDH1A1 (0.63) | MEN1KMT2APTGS1PTGS2MAPT | |
| SCHEMBL11730195 | 0.87 | ALDH1A1 (0.63) | MEN1KMT2APTGS1PTGS2MAPT | |
| Methane SCHEMBL11460137 | 0.87 | ALDH1A1 (0.63) | MEN1KMT2APTGS1PTGS2MAPT | |
| Water SCHEMBL11467024 | 0.86 | ALDH1A1 (0.61) | MEN1KMT2APTGS1PTGS2MAPT | |
| Water SCHEMBL11460877 | 0.86 | ALDH1A1 (0.61) | MEN1KMT2APTGS1PTGS2MAPT | |
| SCHEMBL56645 | 0.85 | MEN1 (0.48) | MEN1KMT2APTGS1PTGS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200360326-A1 | Aqueous Liquid Composition Containing 2-Amino-3-(4-Bromobenzoyl)Phenylacetic Acid | BAUSCH & LOMB INCORPORATED | 2020-11-19 | — | — | US | claimed |
| CN-111712238-A | Eye drops containing 2-amino-3- (4-bromobenzoyl) phenylacetic acid or its salt | 参天制药株式会社 | 2020-09-25 | — | — | CN | claimed |
| EP-2919755-B1 | AQUEOUS LIQUID COMPOSITION CONTAINING 2-AMINO-3-(4-BROMOBENZOYL)PHENYLACETIC ACID | BAUSCH & LOMB (US) | 2018-02-21 | — | — | EP | claimed |
| US-9561277-B2 | Aqueous liquid preparation containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2017-02-07 | — | — | US | claimed |
| WO-2015170177-A1 | AQUEOUS LIQUID PREPARATION CONTAINING 2-AMINO-3-(4-BROMOBENZOYL)PHENYLACETIC ACID | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2015-11-12 | — | — | WO | claimed |
| US-9144609-B2 | Aqueous liquid preparation containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2015-09-29 | — | — | US | claimed |
| US-20150025149-A1 | AQUEOUS LIQUID PREPARATION CONTAINING 2-AMINO-3-(4-BROMOBENZOYL)PHENYLACETIC ACID | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2015-01-22 | — | — | US | claimed |
| US-20150011634-A1 | AQUEOUS LIQUID PREPARATION CONTAINING 2-AMINO-3-(4-BROMOBENZOYL)PHENYLACETIC ACID | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2015-01-08 | — | — | US | claimed |
| US-8927606-B1 | Aqueous liquid preparation containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2015-01-06 | — | — | US | claimed |
| US-8871813-B2 | Aqueous liquid preparation containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2014-10-28 | — | — | US | claimed |
| US-20120115957-A1 | AQUEOUS LIQUID PREPARATION CONTAINING 2-AMINO-3-(4-BROMOBENZOYL)PHENYLACETIC ACID | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2012-05-10 | — | — | US | claimed |
| US-20120095101-A1 | AQUEOUS INTRAOCULAR PENETRATION-PROMOTING EYE DROP | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2012-04-19 | — | — | US | claimed |
| US-8129431-B2 | Aqueous liquid preparation containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2012-03-06 | — | — | US | claimed |
| EP-1808170-B1 | AQUEOUS EYE DROPS WITH ACCELERATED INTRAOCULAR MIGRATION | SENJU PHARMA CO (JP) | 2011-08-17 | — | — | EP | claimed |
| EP-1586316-B1 | AQUEOUS LIQUID PREPARATION CONTAINING 2-AMINO-3-(4-BROMOBENZOYL)PHENYLACETIC ACID | SENJU PHARMA CO (JP) | 2008-04-30 | — | — | EP | claimed |
| US-20070287749-A1 | BROMFENAC OPHTHALMIC FORMULATIONS AND METHODS OF USE | ISTA PHARMACEUTICALS, INC. (US) | 2007-12-13 | — | — | US | claimed |
| EP-1808170-A1 | AQUEOUS EYE DROPS WITH ACCELERATED INTRAOCULAR MIGRATION | Senju Pharmaceutical Co., Ltd. (JP) | 2007-07-18 | — | — | EP | claimed |
| US-20070021507-A1 | Aqueous eye drops with accelerated intraocular migration | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2007-01-25 | — | — | US | claimed |
| US-20050239895-A1 | Aqueous liquid preparation containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2005-10-27 | — | — | US | claimed |
| EP-1586316-A1 | AQUEOUS LIQUID PREPARATION CONTAINING 2-AMINO-3-(4-BROMOBENZOYL)PHENYLACETIC ACID | Senju Pharmaceutical Co., Ltd. (JP) | 2005-10-19 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021507-A1 | Aqueous eye drops with accelerated intraocular migration | AADAT, SLC43A1, IL6 | MEN1 4796/4885KMT2A 2542/4885PTGS1 74/4885 |
| US-20200360326-A1 | Aqueous Liquid Composition Containing 2-Amino-3-(4-Bromobenzoyl)Phenylacetic Acid | AADAT, UACA, IL4 | MEN1 4729/4885KMT2A 1547/4885PTGS1 549/4885 |
| US-20150025149-A1 | AQUEOUS LIQUID PREPARATION CONTAINING 2-AMINO-3-(4-BROMOBENZOYL)PHENYLACETIC ACID | PAOX, FFAR2, FFAR3 | MEN1 4831/4885KMT2A 1176/4885PTGS1 149/4885 |
| US-20150011634-A1 | AQUEOUS LIQUID PREPARATION CONTAINING 2-AMINO-3-(4-BROMOBENZOYL)PHENYLACETIC ACID | PAOX, FFAR2, FFAR3 | MEN1 4831/4885KMT2A 1176/4885PTGS1 149/4885 |
| US-20120095101-A1 | AQUEOUS INTRAOCULAR PENETRATION-PROMOTING EYE DROP | AADAT, SLC43A1, SLC1A5 | MEN1 4747/4885KMT2A 2969/4885PTGS1 163/4885 |
| US-20070287749-A1 | BROMFENAC OPHTHALMIC FORMULATIONS AND METHODS OF USE | TRPC3, AADAC, FFAR3 | MEN1 4864/4885KMT2A 603/4885PTGS1 199/4885 |
| US-20120115957-A1 | AQUEOUS LIQUID PREPARATION CONTAINING 2-AMINO-3-(4-BROMOBENZOYL)PHENYLACETIC ACID | PAOX, FFAR2, FFAR3 | MEN1 4831/4885KMT2A 1176/4885PTGS1 149/4885 |
| US-20050239895-A1 | Aqueous liquid preparation containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid | PAOX, FFAR2, FFAR3 | MEN1 4831/4885KMT2A 1176/4885PTGS1 149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.