Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12384761 | 0.84 | ESR2 (0.41) | ESR2PTGS1KDM4ELMNAALDH1A1 | |
| Terpin SCHEMBL12506199 | 0.75 | PTGS1 (0.36) | ESR2CES2PTGS1TRPA1KDM4E | |
| Terpin SCHEMBL5377815 | 0.75 | TRPA1 (0.40) | ESR2CES2PTGS1TRPA1LMNA | |
| Terpin SCHEMBL9536260 | 0.75 | TRPA1 (0.40) | ESR2CES2PTGS1TRPA1LMNA | |
| Terpin SCHEMBL19192 | 0.75 | TRPA1 (0.40) | ESR2CES2PTGS1TRPA1LMNA | |
| Terpin SCHEMBL29867 | 0.73 | TRPA1 (0.39) | ESR2PTGS1TRPA1LMNAALDH1A1 | |
| Terpin SCHEMBL2487459 | 0.73 | TRPA1 (0.39) | ESR2PTGS1TRPA1LMNAALDH1A1 | |
| SCHEMBL12424446 | 0.72 | ESR2 (0.50) | ESR2KDM4E | |
| SCHEMBL3748819 | 0.72 | ESR2 (0.50) | ESR2KDM4E | |
| SCHEMBL12385989 | 0.72 | ESR2 (0.50) | ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119320309-A | Preparation method and application of 2, 4-polysubstituted-1, 3-cyclobutanediol | 万华化学集团股份有限公司 | 2025-01-17 | — | — | CN | claimed |
| CN-101896474-B | Process for the preparation of ketals and acetals | Xikaidis Co.,Ltd. (US) | 2016-02-03 | — | — | CN | claimed |
| CN-119320309-A | Preparation method and application of 2, 4-polysubstituted-1, 3-cyclobutanediol | 万华化学集团股份有限公司 | 2025-01-17 | — | — | CN | disclosed |
| US-20240361326-A1 | EXOSOMAL LIPIDS AND METABOLITES FOR THE EARLY DETECTION OF HEPATOCELLULAR CARCINOMA | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2024-10-31 | — | — | US | disclosed |
| US-10941092-B2 | Hydroformylation process for producing 1,6-hexanediol derivatives | BASF SE | 2021-03-09 | — | — | US | disclosed |
| EP-3362426-B1 | HYDROFORMYLATION PROCESS FOR PRODUCING 1,6-DISUBSTITUTED HEXANE DERIVATIVES | BASF SE (DE) | 2020-09-02 | — | — | EP | disclosed |
| US-20200172458-A1 | HYDROFORMYLATION PROCESS FOR PRODUCING 1,6-HEXANEDIOL DERIVATIVES | BASF SE (DE) | 2020-06-04 | — | — | US | disclosed |
| US-10647651-B2 | Hydroformylation process for producing 1,6-disubstituted hexane derivatives | BASF SE (DE) | 2020-05-12 | — | — | US | disclosed |
| EP-3638655-A1 | HYDROFORMYLATION PROCESS FOR PRODUCING 1,6-HEXANEDIOL DERIVATIVES | BASF SE (DE) | 2020-04-22 | — | — | EP | disclosed |
| CN-110621663-A | Hydroformylation process for the preparation of 1, 6-hexanediol derivatives | 巴斯夫欧洲公司 | 2019-12-27 | — | — | CN | disclosed |
| WO-2018228879-A1 | HYDROFORMYLATION PROCESS FOR PRODUCING 1,6-HEXANEDIOL DERIVATIVES | BASF SE (DE) | 2018-12-20 | — | — | WO | disclosed |
| US-20110021658-A1 | Polyketal Compounds, Synthesis, and Applications | SEGETIS, INC. (US) | 2011-01-27 | — | — | US | disclosed |
| US-20100292491-A1 | Method of Making Ketals and Acetals | SEGETIS, INC. (US) | 2010-11-18 | — | — | US | disclosed |
| CN-101802052-A | ketal compounds from polyols and oxocarboxylates | SEGETIS INC | 2010-08-11 | — | — | CN | disclosed |
| EP-2209770-A1 | METHOD OF MAKING KETALS AND ACETALS | Segetis, Inc. (US) | 2010-07-28 | — | — | EP | disclosed |
| EP-2205606-A2 | POLYKETAL COMPOUNDS, SYNTHESIS, AND APPLICATIONS | Segetis, Inc. (US) | 2010-07-14 | — | — | EP | disclosed |
| EP-2185625-A1 | KETAL COMPOUNDS FROM POLYOLS AND OXOCARBOXYLATES | Segetis, Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009048874-A1 | METHOD OF MAKING KETALS AND ACETALS | SEGETIS, INC. (US) | 2009-04-16 | — | — | WO | disclosed |
| WO-2009049041-A2 | POLYKETAL COMPOUNDS, SYNTHESIS, AND APPLICATIONS | SEGETIS, INC. (US) | 2009-04-16 | — | — | WO | disclosed |
| WO-2009032905-A1 | KETAL COMPOUNDS FROM POLYOLS AND OXOCARBOXYLATES | SEGETIS, INC. (US) | 2009-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10941092-B2 | Hydroformylation process for producing 1,6-hexanediol derivatives | HPD, DHPS, ADH1A | ESR2 2957/4885CES2 1088/4885PTGS1 542/4885 |
| US-20110021658-A1 | Polyketal Compounds, Synthesis, and Applications | TKT, KYAT1, KHK | ESR2 3177/4885CES2 658/4885PTGS1 808/4885 |
| US-20200172458-A1 | HYDROFORMYLATION PROCESS FOR PRODUCING 1,6-HEXANEDIOL DERIVATIVES | HPD, DHPS, ADH1A | ESR2 2957/4885CES2 1088/4885PTGS1 542/4885 |
| US-20100292491-A1 | Method of Making Ketals and Acetals | KAT6B, KAT5, ADH1C | ESR2 2201/4885CES2 415/4885PTGS1 1321/4885 |
| US-10647651-B2 | Hydroformylation process for producing 1,6-disubstituted hexane derivatives | HPD, HDHD5, ADH1A | ESR2 3642/4885CES2 1073/4885PTGS1 505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.