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Sugi Predict / Compounds / SCHEMBL563295

SCHEMBL563295

SCHEMBL563295

Cc1cc(C#N)cc(C(=O)NC(C)C)c1NC(=O)c1cc(Cl)nn1-c1ncccc1Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KCNH2 Q12809 5/20 0.37
▸ GCK P35557 4/20 0.37
▸ KMT2A Q03164 1/20 0.35
▸ PDE4A P27815 2/20 0.35
▸ PDE4B Q07343 1/20 0.35
▸ PDE4C Q08493 1/20 0.35
▸ PDE4D Q08499 1/20 0.35
▸ PKM P14618 1/20 0.35
▸ EGLN1 Q9GZT9 1/20 0.34
▸ DHODH Q02127 1/20 0.34
▸ ITGB1 P05556 1/20 0.33
▸ ITGAV P06756 1/20 0.33
▸ ITGA5 P08648 1/20 0.33
▸ ITGA4 P13612 1/20 0.33
▸ MALT1 Q9UDY8 1/20 0.33
▸ SLC2A1 P11166 1/20 0.33
▸ SLC2A2 P11168 1/20 0.33
▸ SLC2A3 P11169 1/20 0.33
▸ SLC2A4 P14672 1/20 0.33
▸ CAPN1 P07384 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30078303 1.00 KCNH2 (0.37) KCNH2GCKKMT2APDE4APDE4B
SCHEMBL10140240 0.95 KMT2A (0.35) KCNH2GCKKMT2APDE4APDE4B
SCHEMBL30078383 0.92 DHODH (0.41) KCNH2GCKKMT2APDE4APDE4B
SCHEMBL13650074 0.92 KCNH2 (0.36) KCNH2GCKKMT2APDE4APDE4B
SCHEMBL563173 0.92 DHODH (0.41) KCNH2GCKKMT2APDE4APDE4B
SCHEMBL30845280 0.91 KMT2A (0.36) KCNH2GCKKMT2APDE4APDE4B
SCHEMBL563502 0.91 KMT2A (0.36) KCNH2GCKKMT2APDE4APDE4B
SCHEMBL782483 0.90 MALT1 (0.37) KCNH2KMT2APDE4APDE4BPDE4C
SCHEMBL782144 0.90 KLKB1 (0.37) KCNH2GCKPDE4BSLC2A1SLC2A2
SCHEMBL961226 0.89 SLC2A1 (0.38) KCNH2GCKKMT2APDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247647-B2 Cyano anthranilamide insecticides E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-07-24 — — US claimed
US-20240349727-A1 SYNERGY BETWEEN MIXTURES OF ISOTHIOCYANATES AND COMMERCIAL FUNGICIDES AGROSUSTAIN SA (CH) 2024-10-24 — — US disclosed
CN-117858621-A Synergistic effect between isothiocyanate and mixture of commercial fungicides 农维股份公司 2024-04-09 — — CN disclosed
US-20210378242-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, LLC (US) 2021-12-09 — — US disclosed
US-10405548-B2 Fungicidal compositions SYNGENTA CROP PROTECTION LLC (US) 2019-09-10 — — US disclosed
EP-2547665-B1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-07-04 — — EP disclosed
US-9949482-B2 Fungicidal compositions SYNGENTA CROP PROTECTION, LLC (US) 2018-04-24 — — US disclosed
US-9771365-B2 Spiroheterocyclic N-oxypiperidines as pesticides SYNGENTA PARTICIPATIONS AG (CH) 2017-09-26 — — US disclosed
US-9771365-B2 Spiroheterocyclic N-oxypiperidines as pesticides SYNGENTA PARTICIPATIONS AG (CH) 2017-09-26 — — US disclosed
EP-2187748-B1 FUNGICIDAL COMPOUNDS AND MIXTURES DU PONT (US) 2017-07-05 — — EP disclosed
US-20080182750-A1 Cyano Anthranilamide Insecticides SYNGENTA CROP PROTECTION, INC. (US) 2008-07-31 — — US disclosed
US-20080146552-A1 Anthranilamide Derivatives as Insecticides SYNGENTA CROP PROTECTION, INC. 2008-06-19 — — US disclosed
US-20080146552-A1 Anthranilamide Derivatives as Insecticides SYNGENTA CROP PROTECTION, INC. 2008-06-19 — — US disclosed
US-20070265267-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, INC. (US) 2007-11-15 — — US disclosed
US-20070244073-A1 Pesticidal Mixtures SYNGENTA CROP PROTECTION, INC. (US) 2007-10-18 — — US disclosed
US-20070244073-A1 Pesticidal Mixtures SYNGENTA CROP PROTECTION, INC. (US) 2007-10-18 — — US disclosed
WO-2007080131-A2 ANTHRANILAMIDE DERIVATIVES AND THEIR USE FOR THE CONTROL OF INSECTS AND ACARI SYNGENTA PARTICIPATIONS AG (CH) 2007-07-19 — — WO disclosed
WO-2007068356-A1 INSECTICIDAL COMPOSITIONS WITH IMPROVED EFFECT BAYER CROPSCIENCE AG (DE) 2007-06-21 — — WO disclosed
WO-2007020050-A2 BICYCLIC BISAMIDE DERIVATIVES AND USE THEREOF AS INSECTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2007-02-22 — — WO disclosed
WO-2007009661-A2 PESTICIDAL MIXTURES CONTAINING BICYCLIC ANTHRANILAMIDES SYNGENTA PARTICIPATIONS AG (CH) 2007-01-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210378242-A1 FUNGICIDAL COMPOSITIONS PIK3C3, CYP51A1, CYP1B1 KCNH2 499/4885GCK 2902/4885KMT2A 2404/4885
US-20080146552-A1 Anthranilamide Derivatives as Insecticides DDT, ALDH7A1, AADAC KCNH2 3048/4885GCK 3795/4885KMT2A 678/4885
US-20070265267-A1 FUNGICIDAL COMPOSITIONS CRY1, ERG28, DDT KCNH2 28/4885GCK 700/4885KMT2A 1397/4885
US-20070244073-A1 Pesticidal Mixtures ACHE, ATL3, BPHL KCNH2 1449/4885GCK 3767/4885KMT2A 2564/4885
US-20080182750-A1 Cyano Anthranilamide Insecticides CRY1, CRYAA, ALDH7A1 KCNH2 2382/4885GCK 3717/4885KMT2A 1322/4885
US-10405548-B2 Fungicidal compositions PIK3C3, CYP51A1, CYP1B1 KCNH2 499/4885GCK 2902/4885KMT2A 2404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.