Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 3/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.33 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.33 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL563295 | 0.95 | KCNH2 (0.37) | KMT2APKMEGLN1PDE4AITGB1 | |
| SCHEMBL30078303 | 0.95 | KCNH2 (0.37) | KMT2APKMEGLN1PDE4AITGB1 | |
| SCHEMBL10140237 | 0.91 | KMT2A (0.36) | KMT2APKMEGLN1PDE4APDE4B | |
| SCHEMBL10140235 | 0.90 | PDE4A (0.36) | KMT2APKMEGLN1PDE4AITGB1 | |
| SCHEMBL10140185 | 0.89 | RECQL (0.36) | KMT2APKMPDE4ACAPN1KCNH2 | |
| SCHEMBL10140202 | 0.88 | KLKB1 (0.38) | KMT2ASLC2A1SLC2A2SLC2A3SLC2A4 | |
| SCHEMBL10140151 | 0.87 | PDE4A (0.38) | PKMPDE4ACAPN1KCNH2 | |
| SCHEMBL563173 | 0.87 | DHODH (0.41) | KMT2APKMEGLN1PDE4APDE4B | |
| SCHEMBL13650074 | 0.87 | KCNH2 (0.36) | KMT2APKMEGLN1PDE4APDE4B | |
| SCHEMBL30078383 | 0.87 | DHODH (0.41) | KMT2APKMEGLN1PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9949482-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION, LLC (US) | 2018-04-24 | — | — | US | disclosed |
| US-20170071205-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, LLC (US) | 2017-03-16 | — | — | US | disclosed |
| US-20160302414-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2016-10-20 | — | — | US | disclosed |
| US-9282743-B2 | Chemical compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-15 | — | — | US | disclosed |
| US-9096525-B2 | Iminipyridine derivatives and their uses as microbiocides | SYNGENTA CROP PROTECTION, LLC (US) | 2015-08-04 | — | — | US | disclosed |
| US-20140148339-A1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-05-29 | — | — | US | disclosed |
| US-8536089-B2 | For controlling phytopathogenic diseases; synergistic | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-17 | — | — | US | disclosed |
| US-20130210625-A1 | SPIROHETEROCYCLIC PYRROLIDINE DERIVATIVES BASED PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-15 | — | — | US | disclosed |
| US-8399490-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-19 | — | — | US | disclosed |
| US-20120309812-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-12-06 | — | — | US | disclosed |
| US-8124567-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-8124566-B2 | Synergistic fungicidal compositions | SYNGENTA CROP PROTECTION, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20100273830-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-28 | — | — | US | disclosed |
| US-20100099717-A1 | SUSPENSION CONCENTRATES FOR IMPROVING THE ROOT ABSORPTION OF AGROCHEMICAL ACTIVE INGREDIENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-04-22 | — | — | US | disclosed |
| US-20090149506-A1 | INSECTICIDAL COMPOSITIONS WITH IMPROVED EFFECT | BAYER CROPSCIENCE AG (DE) | 2009-06-11 | — | — | US | disclosed |
| US-20080262044-A1 | Pesticidal Mixtures | SYNGENTA PARTICIPATIONS AG (CH) | 2008-10-23 | — | — | US | disclosed |
| US-20080076664-A1 | Fungicidal Compositions | SYNGENTA CROP PROTECTION, INC. | 2008-03-27 | — | — | US | disclosed |
| US-20080070785-A1 | For controlling phytopathogenic diseases; synergistic | SYNGENTA CROP PROTECTION, INC. (US) | 2008-03-20 | — | — | US | disclosed |
| US-20070265267-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, INC. (US) | 2007-11-15 | — | — | US | disclosed |
| US-20070244121-A1 | Synergistic Fungicidal Compositions | SYNGENTA CROP PROTECTION, INC. (US) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149506-A1 | INSECTICIDAL COMPOSITIONS WITH IMPROVED EFFECT | PTEN, PPA1, NAAA | KMT2A 1949/4885PKM 2171/4885EGLN1 1878/4885 |
| US-20120309812-A1 | INSECTICIDAL COMPOUNDS | ACHE, AADAC, NISCH | KMT2A 1531/4885PKM 2393/4885EGLN1 490/4885 |
| US-20130210625-A1 | SPIROHETEROCYCLIC PYRROLIDINE DERIVATIVES BASED PESTICIDES | DDT, PYCR1, PKD2 | KMT2A 3529/4885PKM 1314/4885EGLN1 1982/4885 |
| US-20100099717-A1 | SUSPENSION CONCENTRATES FOR IMPROVING THE ROOT ABSORPTION OF AGROCHEMICAL ACTIVE INGREDIENTS | CROCC, SLC19A1, ABCB11 | KMT2A 3201/4885PKM 4045/4885EGLN1 988/4885 |
| US-20160302414-A1 | INSECTICIDAL COMPOUNDS | ACHE, AADAC, CASP3 | KMT2A 3045/4885PKM 2201/4885EGLN1 869/4885 |
| US-20100273830-A1 | NOVEL INSECTICIDES | NR5A2, NR2C2, NOX5 | KMT2A 1719/4885PKM 3787/4885EGLN1 4713/4885 |
| US-20070265267-A1 | FUNGICIDAL COMPOSITIONS | CRY1, ERG28, DDT | KMT2A 1397/4885PKM 187/4885EGLN1 1174/4885 |
| US-20070244121-A1 | Synergistic Fungicidal Compositions | DDT, CRY1, HCN1 | KMT2A 2009/4885PKM 174/4885EGLN1 2039/4885 |
| US-20080262044-A1 | Pesticidal Mixtures | DDT, BCHE, ACHE | KMT2A 1275/4885PKM 1355/4885EGLN1 1447/4885 |
| US-20080070785-A1 | For controlling phytopathogenic diseases; synergistic | BROX, EPM2A, MANBA | KMT2A 3493/4885PKM 522/4885EGLN1 1009/4885 |
| US-20140148339-A1 | CHEMICAL COMPOUNDS | DDT, CYP1B1, CYP1A1 | KMT2A 1487/4885PKM 1803/4885EGLN1 258/4885 |
| US-20170071205-A1 | FUNGICIDAL COMPOSITIONS | PIK3C3, CYP51A1, CYP1B1 | KMT2A 2404/4885PKM 1154/4885EGLN1 457/4885 |
| US-20080076664-A1 | Fungicidal Compositions | AKR7A2, CYP51A1, TUBA3C | KMT2A 3265/4885PKM 645/4885EGLN1 1680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.