Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5916036 | 0.75 | PTPN1 (0.42) | ALDH1A1LMNATP53CYP1A2CYP3A4 | |
| SCHEMBL7270394 | 0.74 | — | — | |
| SCHEMBL5085740 | 0.73 | TSHR (0.35) | LMNA | |
| SCHEMBL5677598 | 0.72 | PTPN1 (0.40) | ALDH1A1HPGDMAOAMAOBMAPK1 | |
| SCHEMBL102781 | 0.71 | MEN1 (0.37) | MEN1PLIN1ALDH1A1LMNATP53 | |
| SCHEMBL5677258 | 0.71 | GPR84 (0.50) | — | |
| SCHEMBL28396284 | 0.69 | CDC25A (0.37) | MEN1PLIN1NR1I2USP2ALDH1A1 | |
| SCHEMBL11151876 | 0.67 | GABRA1 (0.33) | ALDH1A1 | |
| SCHEMBL709852 | 0.66 | MAPT (0.39) | MEN1ALDH1A1LMNAGAAMAPT | |
| SCHEMBL216778 | 0.66 | LMNA (0.38) | MEN1PLIN1NR1I2USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060036109-A1 | Tropylideneamines and use thereof | LANXESS DEUTSCHLAND GMBH (DE) | 2006-02-16 | — | — | US | disclosed |
| EP-1614674-A2 | Tropylideneamines and their use | Lanxess Deutschland GmbH (DE) | 2006-01-11 | — | — | EP | disclosed |
| US-20050283014-A1 | Bistropylidenediamines and use thereof | LANXESS DEUTSCHLAND GMBH (DE) | 2005-12-22 | — | — | US | disclosed |
| EP-1604973-A1 | Bistropylidenediamines and their use | Lanxess Deutschland GmbH (DE) | 2005-12-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060036109-A1 | Tropylideneamines and use thereof | PNMT, INMT, HNMT | MEN1 2422/4885PLIN1 4639/4885NR1I2 4212/4885 |
| US-20050283014-A1 | Bistropylidenediamines and use thereof | FHIT, BTD, HNMT | MEN1 740/4885PLIN1 4511/4885NR1I2 4141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.