Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1279982 | 0.91 | — | — | |
| SCHEMBL232367 | 0.80 | — | — | |
| SCHEMBL8539211 | 0.79 | TSHR (0.34) | — | |
| Acrylamide SCHEMBL5565115 | 0.78 | — | — | |
| SCHEMBL7749797 | 0.76 | — | — | |
| SCHEMBL9782578 | 0.75 | — | — | |
| Acrylamide SCHEMBL10876018 | 0.73 | TSHR (0.42) | — | |
| SCHEMBL6558496 | 0.71 | — | — | |
| SCHEMBL6652448 | 0.70 | MMP1 (0.38) | — | |
| SCHEMBL28077512 | 0.70 | TSHR (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115663-B1 | METHOD OF DEWATERING DIFFICULT SLUDGES | NALCO CHEMICAL CO (US) | 2006-09-20 | — | — | EP | claimed |
| EP-1115663-A4 | METHOD OF DEWATERING DIFFICULT SLUDGES | NALCO CHEMICAL CO (US) | 2003-08-13 | — | — | EP | claimed |
| EP-1115663-A1 | METHOD OF DEWATERING DIFFICULT SLUDGES | NALCO CHEMICAL COMPANY (US) | 2001-07-18 | — | — | EP | claimed |
| US-6083404-A | MIXING WITH AN COAGULANT AND FLOCCULANT | NALCO CHEMICAL COMPANY (US) | 2000-07-04 | — | — | US | claimed |
| WO-2000017112-A1 | METHOD OF DEWATERING DIFFICULT SLUDGES | NALCO CHEMICAL COMPANY (US) | 2000-03-30 | — | — | WO | claimed |
| US-20030015219-A1 | Cleaning process and composition | ECOLAB USA INC. | 2003-01-23 | — | — | US | disclosed |