SCHEMBL582819

SCHEMBL582819

O=S(=O)(O)C(CCCO)N1CCNCC1

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.32
LMNA P02545 1/20 0.31
CYP3A4 P08684 1/20 0.31
GABRA1 P14867 1/20 0.31
TSHR P16473 1/20 0.31
GABRG2 P18507 1/20 0.31
NFKB1 P19838 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
GABRA2 P47869 1/20 0.31
GABRA6 Q16445 1/20 0.31
SLC6A2 P23975 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21623674 0.95 SIGMAR1 (0.31) SIGMAR1LMNACYP3A4GABRA1TSHR
SCHEMBL3480504 0.93 SIGMAR1 (0.31) SIGMAR1SLC6A2
SCHEMBL21358779 0.86 SIGMAR1 (0.45) SIGMAR1SLC6A2
SCHEMBL435752 0.82 SIGMAR1 (0.38) SIGMAR1LMNACYP3A4GABRA1TSHR
SCHEMBL28344667 0.82 LMNA (0.31) LMNACYP3A4GABRA1TSHRGABRG2
SCHEMBL5165513 0.81 FDPS (0.32)
SCHEMBL1696717 0.78 OPRD1 (0.35) SIGMAR1LMNACYP3A4GABRA1TSHR
SCHEMBL28508077 0.77 SLC6A2 (0.31) SLC6A2
SCHEMBL16353882 0.77
SCHEMBL28408206 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021238893-A1 EFFICIENT AND EFFECTIVE TISSUE CLEARING AGENTS AND THEIR COMPOSITIONS THE CHINESE UNIVERSITY OF HONG KONG (CN) 2021-12-02 WO claimed
US-20260144849-A1 MEMBRANE FOR GUIDED BONE REGENERATION AND METHOD FOR MANUFACTURING THE SAME Y-Bon Bio Inc. (KR) 2026-05-28 US disclosed
US-20250060375-A1 ALPHA-SYNUCLEIN DETECTION ASSAY The Univ. Court of the Univ. of Edinburgh (GB) 2025-02-20 US disclosed
US-20250011335-A1 SUBSTITUTED PYRIDINES, PYRIDAZINES, PYRIMIDINES, AND 1,2,4-TRIAZINES AS TYK2 INHIBITORS SUDO BIOSCIENCES LIMITED (GB) 2025-01-09 US disclosed
US-12122785-B2 Substituted pyridines, pyridazines, pyrimidines, and 1,2,4-triazines as TYK2 inhibitors SUDO BIOSCIENCES LIMITED (GB) 2024-10-22 US disclosed
US-20240344023-A1 HYDROXYUREA TO ENHANCE SPERM CELLS MEHARRY MEDICAL COLLEGE (US) 2024-10-17 US disclosed
WO-2024119440-A1 BIODEGRADABLE MULTI-BLOCK COPOLYMERS COMPRISING LINKING UNITS DERIVED FROM CYCLIC KETENE ACETAL BASF SE (DE) 2024-06-13 WO disclosed
WO-2024114687-A1 ANTI-TFR1 ANTIBODIES AND USES THEREOF BIOCYTOGEN PHARMACEUTICALS (BEIJING) CO., LTD. (CN) 2024-06-06 WO disclosed
WO-2024109307-A1 A PHARMACEUTICAL COMPOSITION OF A RECOMBINANT ADENO-ASSOCIATED VIRUS VECTOR AND ITS APPLICATION SICHUAN REAL & BEST BIOTECH CO., LTD. (CN) 2024-05-30 WO disclosed
EP-4373945-A1 COMPOSITIONS AND METHODS FOR EFFECTIVE DELIVERY OF POLYNUCLEOTIDES TO CELLS Wuhan University (CN) 2024-05-29 EP disclosed
US-5766879-A ISOLATED NUCLEIC ACID MOLECULE ENCODING SEROTONIN RECEPTORS; DETERMINING LIGAND BINDING, DETECTING EXPRESSION, DRUG SCREENING SYNAPTIC PHARMACEUTICAL CORPORATION (US) 1998-06-16 US disclosed
US-5721252-A PIPERIDINYL-1H-INDOLE DERIVATIVES ELI LILLY AND COMPANY (US) 1998-02-24 US disclosed
US-5708008-A TREATMENT OF MIGRAINE ELI LILLY AND COMPANY (US) 1998-01-13 US disclosed
US-5708187-A MIGRANE HEADACHES ELI LILLY AND COMPANY (US) 1998-01-13 US disclosed
US-5698571-A ADMINISTERING TO THE MAMMAL A AGONIST WHICH POSSESSES A PREFERENTIAL SPECIFICITY INDEX; EXHIBIT MINIMUM VASOCONSTRICTIVE SIDE EFFECT ELI LILLY AND COMPANY (US) 1997-12-16 US disclosed
US-5698530-A A VACCINIA VIRUS INTO WHICH CARCINOEMBRYONIC ANTIGEN GENE IS INSERTETED; INDUCE AN ACTIVE IMMUNE RESPONSE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1997-12-16 US disclosed
US-5693534-A CULTURE MEDIUM COMPRISING HUMAN ACTIVIN AND INHIBIN GENENTECH, INC. (US) 1997-12-02 US disclosed
US-5503975-A PREDICTING IN VITRO METHYLATION PATTERN OF DNA MOLECULE BY DETERMINING NUCLEOTIDE SEQUENCE, DETERMINING WHETHER SEQUENCE INCLUDES SPECIFIED SITE CITY OF HOPE (US) 1996-04-02 US disclosed
EP-0684997-A1 ANTHRAX TOXIN FUSION PROTEINS AND USES THEREOF THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1995-12-06 EP disclosed
WO-1994018332-A2 ANTHRAX TOXIN FUSION PROTEINS AND USES THEREOF THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1994-08-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12122785-B2 Substituted pyridines, pyridazines, pyrimidines, and 1,2,4-triazines as TYK2 inhibitors TYK2, JAK1, PDXK SIGMAR1 4352/4885LMNA 2270/4885CYP3A4 1473/4885
US-20250011335-A1 SUBSTITUTED PYRIDINES, PYRIDAZINES, PYRIMIDINES, AND 1,2,4-TRIAZINES AS TYK2 INHIBITORS TYK2, PDXK, JAK1 SIGMAR1 4483/4885LMNA 2207/4885CYP3A4 1736/4885
US-20240344023-A1 HYDROXYUREA TO ENHANCE SPERM CELLS NASP, ACR, CATSPER1 SIGMAR1 2069/4885LMNA 1847/4885CYP3A4 4676/4885
US-20260144849-A1 MEMBRANE FOR GUIDED BONE REGENERATION AND METHOD FOR MANUFACTURING THE SAME BMP2, BMPR2, BMPR1B SIGMAR1 1380/4885LMNA 2006/4885CYP3A4 4566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.