Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | TLR3 | O15455 | 2/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130857 | 0.82 | ALOX15 (0.38) | HTTPOLBSMN1; SMN2ALOX15ALOX12 | |
| SCHEMBL2298411 | 0.81 | TLR3 (0.34) | CYP3A4HTTALOX15ALOX12TLR3 | |
| SCHEMBL1428264 | 0.71 | CYP1A2 (0.36) | — | |
| SCHEMBL37664 | 0.69 | HTR2A (0.62) | HTR2AHTTRAB9A | |
| SCHEMBL2840091 | 0.69 | HTR2A (0.58) | CYP3A4HTR2AHTTPOLBSMN1; SMN2 | |
| SCHEMBL7203836 | 0.67 | RAB9A (0.60) | HTTPOLBPKMLMNAALOX15 | |
| SCHEMBL6141153 | 0.66 | HTR2A (0.59) | HTR2AHTTPOLBSMN1; SMN2LMNA | |
| SCHEMBL32690826 | 0.66 | HTR2A (0.55) | HTR2AHTTPOLBSMN1; SMN2RAB9A | |
| SCHEMBL669310 | 0.65 | CYP3A4 (0.67) | CYP3A4HTTSMN1; SMN2PKMMEN1 | |
| SCHEMBL6645015 | 0.64 | RAB9A (0.61) | HTR2AHTTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160075680-A1 | MODIFIED SOLID SUPPORT FOR THE SYNTHESIS OF OLIGONUCLEOTIDES | FUNDACION IMDEA NANOCIENCIA (ES) | 2016-03-17 | — | — | US | claimed |
| EP-2992002-A1 | MODIFIED SOLID SUPPORT FOR THE SYNTHESIS OF OLIGONUCLEOTIDES | Fundación Imdea Nanociencia (ES) | 2016-03-09 | — | — | EP | claimed |
| WO-2014177533-A1 | MODIFIED SOLID SUPPORT FOR THE SYNTHESIS OF OLIGONUCLEOTIDES | FUNDACIÓN IMDEA NANOCIENCIA (ES) | 2014-11-06 | — | — | WO | claimed |
| EP-2799443-A1 | Modified solid support for the synthesis of oligonucleotides | Fundación Imdea Nanociencia (ES) | 2014-11-05 | — | — | EP | claimed |
| EP-1091972-A1 | REUSABLE SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 2001-04-18 | — | — | EP | claimed |
| WO-2000001711-A1 | REUSABLE SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 2000-01-13 | — | — | WO | claimed |
| US-20160075680-A1 | MODIFIED SOLID SUPPORT FOR THE SYNTHESIS OF OLIGONUCLEOTIDES | FUNDACION IMDEA NANOCIENCIA (ES) | 2016-03-17 | — | — | US | disclosed |
| EP-2992002-A1 | MODIFIED SOLID SUPPORT FOR THE SYNTHESIS OF OLIGONUCLEOTIDES | Fundación Imdea Nanociencia (ES) | 2016-03-09 | — | — | EP | disclosed |
| WO-2014177533-A1 | MODIFIED SOLID SUPPORT FOR THE SYNTHESIS OF OLIGONUCLEOTIDES | FUNDACIÓN IMDEA NANOCIENCIA (ES) | 2014-11-06 | — | — | WO | disclosed |
| EP-2799443-A1 | Modified solid support for the synthesis of oligonucleotides | Fundación Imdea Nanociencia (ES) | 2014-11-05 | — | — | EP | disclosed |
| US-7135564-B1 | Reusable solid support for oligonucleotide synthesis | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 2006-11-14 | — | — | US | disclosed |
| EP-0877751-B1 | LINKER ARM FOR SOLID SUPPORT OLIGONUCLEOTIDE SYNTHESIS AND PROCESS FOR PRODUCTION THEREOF | UNIV TECHNOLOGIES INT (CA) | 2003-10-15 | — | — | EP | disclosed |
| EP-0876390-B1 | REUSABLE SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS, PROCESS FOR PRODUCTION THEREOF AND PROCESS FOR USE THEREOF | UNIV TECHNOLOGIES INT (CA) | 2002-06-12 | — | — | EP | disclosed |
| US-6043353-A | FOR SOLID PHASE SYNTHESIS | UNIVERSITY TECHNOLOGIES INTERNATIONAL, INC. (CA) | 2000-03-28 | — | — | US | disclosed |
| US-6015895-A | REACTING A LINKER COMPOUND WITH A HYDROXY GROUP OF A NUCLEOSIDE AND A SOLID SUPPORT CAPABLE OF ESTERIFICATION; LINKER IS STABILE AGAINST SPONTANEOUS HYDROLYSIS AND EASILY CLEAVED WHEN NECESSARY | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 2000-01-18 | — | — | US | disclosed |
| WO-2000001711-A1 | REUSABLE SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 2000-01-13 | — | — | WO | disclosed |
| EP-0877751-A1 | LINKER ARM FOR SOLID SUPPORT OLIGONUCLEOTIDE SYNTHESIS AND PROCESS FOR PRODUCTION THEREOF | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 1998-11-18 | — | — | EP | disclosed |
| EP-0876390-A1 | REUSABLE SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS, PROCESS FOR PRODUCTION THEREOF AND PROCESS FOR USE THEREOF | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997023496-A1 | REUSABLE SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS, PROCESS FOR PRODUCTION THEREOF AND PROCESS FOR USE THEREOF | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 1997-07-03 | — | — | WO | disclosed |
| WO-1997023497-A1 | LINKER ARM FOR SOLID SUPPORT OLIGONUCLEOTIDE SYNTHESIS AND PROCESS FOR PRODUCTION THEREOF | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 1997-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075680-A1 | MODIFIED SOLID SUPPORT FOR THE SYNTHESIS OF OLIGONUCLEOTIDES | POLR2H, POLRMT, POLR2E | CYP3A4 4218/4885HTR2A 4597/4885HTT 2578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.