SCHEMBL5865895

SCHEMBL5865895

CCc1ccc(C(=O)C(F)(F)F)cc1

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 13/20 0.59
NPC1 O15118 1/20 0.58
CYP1A2 P05177 1/20 0.58
CYP2C19 P33261 1/20 0.58
RAB9A P51151 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
ALDH1A1 P00352 1/20 0.57
CES1 P23141 1/20 0.54
PLK1 P53350 1/20 0.52
HDAC4 P56524 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
LMNA P02545 1/20 0.47
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29137248 0.86 ALDH1A1 (0.55) MLYCDNPC1CYP1A2CYP2C19RAB9A
SCHEMBL9560910 0.84 MLYCD (0.57) MLYCDNPC1RAB9AALDH1A1CES1
SCHEMBL3128806 0.82 ALDH1A1 (0.55) MLYCDNPC1CYP1A2CYP2C19RAB9A
SCHEMBL3266774 0.81 MLYCD (0.58) MLYCDALDH1A1PLK1
SCHEMBL7051795 0.81 CES1 (0.56) MLYCDCES1
SCHEMBL1628100 0.81 ALDH1A1 (0.59) NPC1CYP1A2CYP2C19RAB9ASMN1; SMN2
SCHEMBL7051793 0.81 CES1 (0.56) MLYCDCES1
SCHEMBL13668085 0.80 THRA (0.56) MLYCDCES1
SCHEMBL9770874 0.80 ALDH1A1 (0.48) MLYCDNPC1CYP1A2CYP2C19RAB9A
SCHEMBL26660468 0.80 FAAH (0.64) MLYCDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250163224-A1 POLYMER AND PREPARATION METHOD THEREFOR, AND ANION-EXCHANGE MEMBRANE Tan Kah Kee Innovation Laboratory (CN) 2025-05-22 US claimed
US-12297327-B1 Polymer and preparation method therefor, and anion-exchange membrane Tan Kah Kee Innovation Laboratory (CN) 2025-05-13 US claimed
WO-2023217050-A1 POLYMER AND PREPARATION METHOD THEREFOR, AND ANION-EXCHANGE MEMBRANE 嘉庚创新实验室 2023-11-16 WO claimed
CN-114989437-A Polymer, preparation method thereof and anion exchange membrane 嘉庚创新实验室 2022-09-02 CN claimed
US-7087789-B2 Methods for nucleophilic fluoromethylation UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2006-08-08 US claimed
US-20250163224-A1 POLYMER AND PREPARATION METHOD THEREFOR, AND ANION-EXCHANGE MEMBRANE Tan Kah Kee Innovation Laboratory (CN) 2025-05-22 US disclosed
US-12297327-B1 Polymer and preparation method therefor, and anion-exchange membrane Tan Kah Kee Innovation Laboratory (CN) 2025-05-13 US disclosed
WO-2023217050-A1 POLYMER AND PREPARATION METHOD THEREFOR, AND ANION-EXCHANGE MEMBRANE 嘉庚创新实验室 2023-11-16 WO disclosed
CN-110862299-B Method for synthesizing 9-hydroxy-9 trifluoromethyl fluorene compound 浙江工业大学 2022-10-11 CN disclosed
CN-114989437-A Polymer, preparation method thereof and anion exchange membrane 嘉庚创新实验室 2022-09-02 CN disclosed
CN-110862299-A Method for synthesizing 9-hydroxy-9 trifluoromethyl fluorene compound 浙江工业大学 2020-03-06 CN disclosed
WO-2015187684-A1 TANK-BINDING KINASE INHIBITOR COMPOUNDS GILEAD SCIENCES, INC. (US) 2015-12-10 WO disclosed
US-20150031668-A1 CHROMAN DERIVATIVES AS TRPM8 INHIBITORS AMGEN INC (US) 2015-01-29 US disclosed
US-20110070657-A1 DETECTING IONS AND MEASURING ION CONCENTRATIONS THE GENERAL HOSPITAL CORPORATION (US) 2011-03-24 US disclosed
EP-1045836-B1 PYRIDONES AS SRC FAMILY SH2 DOMAIN INHIBITORS BOEHRINGER INGELHEIM PHARMA (US) 2008-03-05 EP disclosed
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
US-4840971-A INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150031668-A1 CHROMAN DERIVATIVES AS TRPM8 INHIBITORS TRPM8, TRPM5, TRPM7 MLYCD 2833/4885NPC1 702/4885CYP1A2 2160/4885
US-20110070657-A1 DETECTING IONS AND MEASURING ION CONCENTRATIONS CA2, SLC30A5, CA3 MLYCD 3370/4885NPC1 453/4885CYP1A2 4254/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.