Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.40 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1283040 | 0.98 | CA2 (0.41) | CA1CA2NFKB1CYP3A4TSHR | |
| SCHEMBL9651092 | 0.98 | CA2 (0.41) | CA1CA2NFKB1CYP3A4TSHR | |
| SCHEMBL626430 | 0.98 | CA2 (0.41) | CA1CA2NFKB1CYP3A4TSHR | |
| SCHEMBL7096164 | 0.98 | CA2 (0.41) | CA1CA2NFKB1CYP3A4TSHR | |
| SCHEMBL7095267 | 0.98 | CA2 (0.41) | CA1CA2NFKB1CYP3A4TSHR | |
| SCHEMBL7098222 | 0.98 | CA2 (0.41) | CA1CA2NFKB1CYP3A4TSHR | |
| SCHEMBL7098262 | 0.98 | CA2 (0.41) | CA1CA2NFKB1CYP3A4TSHR | |
| SCHEMBL7100030 | 0.98 | CA2 (0.41) | CA1CA2NFKB1CYP3A4TSHR | |
| SCHEMBL223461 | 0.98 | CA2 (0.41) | CA1CA2NFKB1CYP3A4TSHR | |
| SCHEMBL7207850 | 0.98 | CA2 (0.41) | CA1CA2NFKB1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673417-B1 | SOLID-LIQUID SEPARATION OF OIL-BASED MUDS | KEMIRA OYJ (FI) | 2016-02-24 | — | — | EP | claimed |
| WO-2011065855-A1 | \"BIOCOMPOSTABLE POLYMER BLENDS\ | CABOPOL - INDÚSTRIA DE COMPOSTOS, S.A. (PT) | 2011-06-03 | — | — | WO | claimed |
| US-20100184816-A1 | Method for Reducing the Phytotoxicity of Azoles on Dicotyledonous Plants by Adding Additives | BAYER CROPSCIENCE AG (DE) | 2010-07-22 | — | — | US | claimed |
| US-7758684-B2 | Ink additive and ink using same | NISSIN CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-07-20 | — | — | US | claimed |
| EP-1982712-A1 | PHARMACEUTICAL FORMULATIONS IN THE FORM OF SOLIDS, SEMISOLIDS, IN SUSPENSION, IN SOLUTION, IN EMULSION OR IN SYRUP, CONTAINING CLINDAMYCIN AND ONE OR MORE MEMBERS OF THE AZOLE FAMILY | WORLD-TRADE IMPORT-EXPORT, WTIE, A.G. (CH) | 2008-10-22 | — | — | EP | claimed |
| EP-1935424-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING COMBINED ANTIDIABETIC SUBSTANCES FOR USE IN DIABETES MELLITUS | ESPINOZA ABDALA, Leopoldo de Jesús (MX) | 2008-06-25 | — | — | EP | claimed |
| US-7381332-B2 | Solid-liquid separation of oil-based muds | KEMIRA OYJ (FI) | 2008-06-03 | — | — | US | claimed |
| EP-1913936-A1 | SUBLINGUAL SOLID PHARMACEUTICAL FORMULATIONS CONTAINING MELOXICAM | ESPINOZA ABDALA, Leopoldo de Jesús (MX) | 2008-04-23 | — | — | EP | claimed |
| US-20070283845-A1 | Ink additive and ink using same | NISSIN CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-12-13 | — | — | US | claimed |
| US-7138079-B2 | Methods for making foamed elastomer gels | EDIZONE, LC (US) | 2006-11-21 | — | — | US | claimed |
| EP-1673417-A2 | SOLID-LIQUID SEPARATION OF OIL-BASED MUDS | Cytec Technology Corp. (US) | 2006-06-28 | — | — | EP | claimed |
| US-20050222281-A1 | Solid blowing agent preparations and process for their preparation | LANXESS DEUTSCHLAND GMBH (DE) | 2005-10-06 | — | — | US | claimed |
| US-20050222282-A1 | Solid blowing agent preparations and process for their preparation | LANXESS DEUTSCHLAND GMBH (DE) | 2005-10-06 | — | — | US | claimed |
| WO-2005035934-A2 | SOLID-LIQUID SEPARATION OF OIL-BASED MUDS | CYTEC TECHNOLOGY CORP. (US) | 2005-04-21 | — | — | WO | claimed |
| US-20050067194-A1 | Solid-liquid separation of oil-based muds | KEMIRA OYJ (FI) | 2005-03-31 | — | — | US | claimed |
| US-20030236313-A1 | Methods for making foamed elastomer gels | EDIZONE, LC | 2003-12-25 | — | — | US | claimed |
| US-6627108-B1 | Salicylic acid, nitrilotriacetic acid, sodium hydroxide, n,n-di-secbutylaminophenol, polyalkylene methylpolysiloxane and water; efficient elemental sulfur recovery | INSTITUT FRANCAIS DU PETROLE (FR) | 2003-09-30 | — | — | US | claimed |
| US-6391953-B1 | FATTY ACID METAL SALT AND ANTIAGGLOMERANT MIXTURE OF POLYSILOXANE AND MINERAL OIL | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-21 | — | — | US | claimed |
| US-6139764-A | A BIODEGRADABLE COATING AGENT FOR COATING FIBERS, COMPRISING BIODEGRADABLE MINERAL OIL SUCH AS METAL SALT OF UNSATURATED OR UNDATURATED FATTY ACID HAVING SPECIFIC VISCOSITY, DENSITY AND VISCOSITY/DENSITY CONSTANT | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-31 | — | — | US | claimed |
| US-4985162-A | SULFOSUCCINATE, NONIONIC SURFACTANT, ANTIFOAM AGENT | WEN-DON CORPORATION (US) | 1991-01-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184816-A1 | Method for Reducing the Phytotoxicity of Azoles on Dicotyledonous Plants by Adding Additives | AS3MT, STS, IPMK | CA1 198/4885CA2 9/4885NFKB1 2762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.