Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | GLA | P06280 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | PLAU | P00749 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | SCNN1A | P37088 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31471091 | 0.83 | PLAU (0.32) | ALDH1A1PLAUKMT2A | |
| SCHEMBL362613 | 0.83 | PLAU (0.32) | ALDH1A1PLAUKMT2A | |
| SCHEMBL29209630 | 0.82 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL11837238 | 0.82 | ALDH1A1 (0.39) | ALDH1A1KDM4EGLAHPGDHSD17B10 | |
| SCHEMBL20799620 | 0.80 | PLAU (0.33) | ALDH1A1PLAUKMT2A | |
| SCHEMBL31289724 | 0.77 | LMNA (0.39) | ALDH1A1LMNAHTTKMT2A | |
| SCHEMBL29209568 | 0.76 | TDP1 (0.32) | TDP1 | |
| SCHEMBL30881607 | 0.76 | TDP1 (0.32) | TDP1 | |
| SCHEMBL30519316 | 0.76 | — | — | |
| SCHEMBL1732884 | 0.76 | ALDH1A1 (0.37) | ALDH1A1KDM4EGLAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3700578-B1 | SYSTEMS FOR RENAL FUNCTION DETERMINATION | MEDIBEACON INC (US) | 2025-12-03 | — | — | EP | disclosed |
| US-12303570-B2 | Compositions and methods for assessing eye vasculature | MEDIBEACON INC. (US) | 2025-05-20 | — | — | US | disclosed |
| US-20230173111-A1 | COMPOSITIONS AND SYSTEMS FOR RENAL FUNCTION DETERMINATION | MEDIBEACON INC. | 2023-06-08 | — | — | US | disclosed |
| US-20230173111-A1 | COMPOSITIONS AND SYSTEMS FOR RENAL FUNCTION DETERMINATION | MEDIBEACON INC. | 2023-06-08 | — | — | US | disclosed |
| US-20230173111-A1 | COMPOSITIONS AND SYSTEMS FOR RENAL FUNCTION DETERMINATION | MEDIBEACON INC. | 2023-06-08 | — | — | US | disclosed |
| US-20230158175-A1 | METHODS FOR RENAL FUNCTION DETERMINATION | MEDIBEACON INC. | 2023-05-25 | — | — | US | disclosed |
| US-20230158175-A1 | METHODS FOR RENAL FUNCTION DETERMINATION | MEDIBEACON INC. | 2023-05-25 | — | — | US | disclosed |
| US-20230158175-A1 | METHODS FOR RENAL FUNCTION DETERMINATION | MEDIBEACON INC. | 2023-05-25 | — | — | US | disclosed |
| US-20230132384-A9 | COMPOSITIONS AND METHODS FOR ASSESSING EYE VASCULATURE | MEDIBEACON INC. | 2023-04-27 | — | — | US | disclosed |
| US-20230132384-A9 | COMPOSITIONS AND METHODS FOR ASSESSING EYE VASCULATURE | MEDIBEACON INC. | 2023-04-27 | — | — | US | disclosed |
| US-20090198053-A1 | Pyrazine Derivatives and Uses Thereof in Renal Monitoring | MEDIBEACON INC. | 2009-08-06 | — | — | US | disclosed |
| US-20090198053-A1 | Pyrazine Derivatives and Uses Thereof in Renal Monitoring | MEDIBEACON INC. | 2009-08-06 | — | — | US | disclosed |
| US-20090198053-A1 | Pyrazine Derivatives and Uses Thereof in Renal Monitoring | MEDIBEACON INC. | 2009-08-06 | — | — | US | disclosed |
| CN-101472903-A | Pyrazine derivatives with extended conjugation and uses thereof | MALLINCKRODT INC (US) | 2009-07-01 | — | — | CN | disclosed |
| EP-2038261-A2 | PYRAZINE DERIVATIVES WITH EXTENDED CONJUGATION AND USES THEREOF | Mallinckrodt Inc. (US) | 2009-03-25 | — | — | EP | disclosed |
| EP-2029554-A1 | PYRAZINE DERIVATIVES AND USES THEREOF IN RENAL MONITORING | Mallinckrodt, Inc. (US) | 2009-03-04 | — | — | EP | disclosed |
| CN-101351454-A | Pyrazine derivatives and their use in renal monitoring | MALLINCKRODT INC (US) | 2009-01-21 | — | — | CN | disclosed |
| WO-2007149478-A2 | PYRAZINE DERIVATIVES WITH EXTENDED CONJUGATION AND USES THEREOF | MALLINCKRODT INC. (US) | 2007-12-27 | — | — | WO | disclosed |
| WO-2007149479-A1 | PYRAZINE DERIVATIVES AND USES THEREOF IN RENAL MONITORING | MALLINCKRODT INC. (US) | 2007-12-27 | — | — | WO | disclosed |
| WO-2007149479-A1 | PYRAZINE DERIVATIVES AND USES THEREOF IN RENAL MONITORING | MALLINCKRODT INC. (US) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230132384-A9 | COMPOSITIONS AND METHODS FOR ASSESSING EYE VASCULATURE | LIPG, FLT4, FABP3 | ALDH1A1 1933/4885KDM4E 4110/4885GLA 231/4885 |
| US-20230173111-A1 | COMPOSITIONS AND SYSTEMS FOR RENAL FUNCTION DETERMINATION | GLS, ATP6V1B1, REN | ALDH1A1 3528/4885KDM4E 4756/4885GLA 873/4885 |
| US-20090198053-A1 | Pyrazine Derivatives and Uses Thereof in Renal Monitoring | GLS, CYP3A5, PYCR1 | ALDH1A1 268/4885KDM4E 2058/4885GLA 3357/4885 |
| US-20230158175-A1 | METHODS FOR RENAL FUNCTION DETERMINATION | GLS, SHBG, OGFR | ALDH1A1 1776/4885KDM4E 4201/4885GLA 347/4885 |
| US-12303570-B2 | Compositions and methods for assessing eye vasculature | LIPG, FLT4, FABP3 | ALDH1A1 1933/4885KDM4E 4110/4885GLA 231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.