Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | UQCRB | P14927 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5899544 | 0.85 | KAT6A (0.58) | ALDH1A1MEN1KMT2AHDAC8HDAC6 | |
| SCHEMBL5899469 | 0.84 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2ANPC1RECQL | |
| SCHEMBL5320466 | 0.84 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ANPC1RECQL | |
| SCHEMBL23014361 | 0.81 | KAT6A (0.58) | ALDH1A1MEN1KMT2AKAT6ALMNA | |
| SCHEMBL5899482 | 0.81 | L3MBTL1 (0.60) | ALDH1A1MEN1KMT2AKAT6AMAPT | |
| SCHEMBL5899737 | 0.81 | MMP1 (0.63) | ALDH1A1MEN1KMT2AKAT6AMAPT | |
| SCHEMBL5899468 | 0.80 | MEN1 (0.67) | ALDH1A1MEN1KMT2AHDAC3HDAC8 | |
| SCHEMBL5899447 | 0.78 | MMP2 (0.70) | ALDH1A1KAT6ALMNAMMP1GAA | |
| SCHEMBL5899480 | 0.77 | KAT6A (0.54) | ALDH1A1MEN1KMT2ANPC1RECQL | |
| SCHEMBL268855 | 0.76 | RAB9A (0.73) | ALDH1A1MEN1KMT2ANPC1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | WYETH | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | HSD11B1, HSD11B2, HSD3B1 | ALDH1A1 139/4885MEN1 1269/4885KMT2A 1509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.