Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 2/20 | 0.37 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6854970 | 0.84 | KMT2A (0.50) | FAAHPDE10AALDH1A1LMNAKDM4E | |
| SCHEMBL6853013 | 0.83 | HRH3 (0.48) | FAAHPDE10AALDH1A1PIK3CDBACE1 | |
| SCHEMBL6853077 | 0.80 | HTR2B (0.49) | FAAHALDH1A1KDM4EHTTKMT2A | |
| SCHEMBL6848678 | 0.80 | TACR2 (0.53) | FAAHPDE10ALMNAPIK3CDBACE1 | |
| SCHEMBL6848935 | 0.80 | SLC2A1 (0.44) | FAAHPDE10AALDH1A1PIK3CDBACE1 | |
| SCHEMBL5442168 | 0.80 | PDE10A (0.43) | FAAHPDE10AALDH1A1PIK3CDPIK3CG | |
| SCHEMBL6853643 | 0.79 | TSHR (0.55) | ALDH1A1LMNAKDM4EHTTMEN1 | |
| SCHEMBL6853186 | 0.79 | LDHA (0.49) | FAAHPDE10APIK3CDBACE1PIK3CG | |
| SCHEMBL5945358 | 0.79 | SLC2A1 (0.46) | FAAHPDE10APIK3CDPIK3CGAKT1 | |
| SCHEMBL6851670 | 0.78 | PDE10A (0.43) | FAAHPDE10AALDH1A1PIK3CDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060223819-A1 | Quinoline Derivatives as NK-3 Antagonists | GlaxoSmithKline S.P.A. & Laboratoire | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223819-A1 | Quinoline Derivatives as NK-3 Antagonists | KCNK3, KCNQ3, KCNN3 | FAAH 2821/4885PDE10A 1613/4885ALDH1A1 2191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.