Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL11779407 | 1.00 | CA1 (0.33) | CA1CA4CA5ACA5BLMNA | |
| Pyrophosphoric Acid SCHEMBL1666234 | 1.00 | CA1 (0.33) | CA1CA4CA5ACA5BLMNA | |
| Pyrophosphoric Acid SCHEMBL452253 | 1.00 | CA1 (0.33) | CA1CA4CA5ACA5BLMNA | |
| Pyrophosphoric Acid SCHEMBL7106242 | 1.00 | CA1 (0.33) | CA1CA4CA5ACA5BLMNA | |
| Pyrophosphoric Acid SCHEMBL27905891 | 0.96 | CA1 (0.32) | CA1CA4CA5ACA5BLMNA | |
| Pyrophosphoric Acid SCHEMBL5051591 | 0.96 | CA1 (0.32) | CA1CA4CA5ACA5BLMNA | |
| Pyrophosphoric Acid SCHEMBL3409500 | 0.96 | CA1 (0.32) | CA1CA4CA5ACA5BLMNA | |
| Pyrophosphoric Acid SCHEMBL4418857 | 0.96 | LMNA (0.35) | CA1CA4CA5ACA5BLMNA | |
| Pyrophosphoric Acid SCHEMBL18670526 | 0.96 | LMNA (0.35) | CA1CA4CA5ACA5BLMNA | |
| Pyrophosphoric Acid SCHEMBL184653 | 0.96 | LMNA (0.35) | CA1CA4CA5ACA5BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5220875-A | Reacting sulfur dioxide with calcined sorbent in presence of oxygen to form solid inorganic sulfate | AMERICAN OXYCARB CORPORATION (US) | 1993-06-22 | — | — | US | claimed |
| US-9073795-B2 | Method for mitigating solid precipitation in fertilizer dispensing system | VERDESIAN LIFE SCIENCES, LLC (US) | 2015-07-07 | — | — | US | disclosed |
| US-20140298721-A1 | METHOD FOR MITIGATING SOLID PRECIPITATION IN FERTILIZER DISPENSING SYSTEM | GLAS AMERICAS LLC | 2014-10-09 | — | — | US | disclosed |
| WO-1994008896-A1 | SLOW RELEASE FERTILIZER AND ACTIVE SYNTHETIC SOIL | LUNDEEN, DANIEL, N. (US) | 1994-04-28 | — | — | WO | disclosed |
| US-5220875-A | Reacting sulfur dioxide with calcined sorbent in presence of oxygen to form solid inorganic sulfate | AMERICAN OXYCARB CORPORATION (US) | 1993-06-22 | — | — | US | disclosed |
| US-5162600-A | Contacting with calcium orthophosphate to form water insoluble lead compounds | RHEOX, INC. (US) | 1992-11-10 | — | — | US | disclosed |
| US-4464486-A | ALKALI METAL OR AMMONIUM SILICATES, INSULATION, OREANIC-INORGANIC FOAMS | CIBA-GEIGY CORPORATION (US) | 1984-08-07 | — | — | US | disclosed |
| US-3951834-A | Foamed products from sodium silicate | OWENS-CORNING FIBERGLAS CORPORATION (US) | 1976-04-20 | — | — | US | disclosed |