Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28090496 | 0.70 | MGLL (0.54) | PKM | |
| SCHEMBL17047745 | 0.67 | PARP1 (0.40) | HCAR1NPC1MAPTPKMRAB9A | |
| SCHEMBL8980795 | 0.66 | KMT2A (0.50) | RAB9A | |
| SCHEMBL6337999 | 0.65 | FAAH (0.53) | PTPRCNPC1MAPTRAB9A | |
| SCHEMBL1471136 | 0.63 | MGLL (0.47) | MAPTPKM | |
| SCHEMBL1471314 | 0.63 | MEN1 (0.54) | NPC1MAPTRAB9A | |
| SCHEMBL21478341 | 0.63 | MEN1 (0.38) | HCAR1NPC1MAPTPKMRAB9A | |
| SCHEMBL1471161 | 0.61 | MAPT (0.50) | PTPRCALOX5NPC1MAPTRAB9A | |
| SCHEMBL15731559 | 0.61 | CYP2A6 (0.42) | CYP2A6CYP2E1CYP2B6PTPRC | |
| SCHEMBL1471536 | 0.60 | RGS4 (0.57) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220526-A1 | COMPOSITIONS AND METHODS FOR MODULATING DOPAMINE RECEPTOR ACTIVITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-11-16 | — | — | WO | disclosed |
| US-20230173090-A1 | COMPOSITIONS AND METHODS FOR MODULATING DOPAMINE RECEPTOR ACTIVITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-06-08 | — | — | US | disclosed |
| WO-2023097186-A1 | COMPOSITIONS AND METHODS FOR ENHANCING VISUAL FUNCTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-01 | — | — | WO | disclosed |
| EP-4172187-A1 | COMPOSITIONS AND METHODS FOR MODULATING DOPAMINE RECEPTOR ACTIVITY | The Regents of the University of California (US) | 2023-05-03 | — | — | EP | disclosed |
| EP-4158002-A1 | COMPOSITIONS AND METHODS FOR ENHANCING VISUAL FUNCTION | The Regents of the University of California (US) | 2023-04-05 | — | — | EP | disclosed |
| WO-2022006071-A1 | COMPOSITIONS AND METHODS FOR MODULATING DOPAMINE RECEPTOR ACTIVITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-01-06 | — | — | WO | disclosed |
| WO-2021243086-A1 | COMPOSITIONS AND METHODS FOR ENHANCING VISUAL FUNCTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-12-02 | — | — | WO | disclosed |
| US-20210369744-A1 | COMPOSITIONS AND METHODS FOR ENHANCING VISUAL FUNCTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-12-02 | — | — | US | disclosed |
| US-20200308539-A1 | AFFINITY-TAGGED PHOTOSWITCHES AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-10-01 | — | — | US | disclosed |
| EP-3684787-A1 | AFFINITY-TAGGED PHOTOSWITCHES AND METHODS OF USE THEREOF | The Regents of The University of California (US) | 2020-07-29 | — | — | EP | disclosed |
| US-8309350-B2 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-11-13 | — | — | US | disclosed |
| US-20120190094-A1 | Photoreactive Regulator of Protein Function and Methods of Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2012-07-26 | — | — | US | disclosed |
| US-8178496-B2 | Photoreactive regulator of glutamate receptor function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-05-15 | — | — | US | disclosed |
| US-8114843-B2 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-02-14 | — | — | US | disclosed |
| US-20110207213-A1 | Photoreactive Synthetic Regulator of Protein Function and Methods of Use Thereof | ENERGY, UNITED STATES DEPARTMENT OF | 2011-08-25 | — | — | US | disclosed |
| US-20100330607-A1 | PHOTOSWITCH-ENABLED ION CHANNEL ASSAY SYSTEM | PHOTOSWITCH BIOSCIENCES, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| WO-2010151609-A1 | PHOTOSWITCH-ENABLED ION CHANNEL ASSAY SYSTEM | PHOTOSWITCH BIOSCIENCES INC. (US) | 2010-12-29 | — | — | WO | disclosed |
| WO-2010051343-A1 | PHOTOREACTIVE SYNTHETIC REGULATOR OF PROTEIN FUNCTION AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-05-06 | — | — | WO | disclosed |
| US-20090181454-A1 | PHOTOREACTIVE REGULATOR OF GLUTAMATE RECEPTOR FUNCTION AND METHODS OF USE THEREOF | ENERGY, UNITED STATE DEPARTMENT OF | 2009-07-16 | — | — | US | disclosed |
| US-20070128662-A1 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210369744-A1 | COMPOSITIONS AND METHODS FOR ENHANCING VISUAL FUNCTION | PDE6C, UACA, EPHA2 | CYP2A6 4645/4885CYP2E1 4878/4885CYP2B6 4649/4885 |
| US-20090181454-A1 | PHOTOREACTIVE REGULATOR OF GLUTAMATE RECEPTOR FUNCTION AND METHODS OF USE THEREOF | GRM2, GRM1, GRM3 | CYP2A6 4490/4885CYP2E1 4838/4885CYP2B6 4669/4885 |
| US-20200308539-A1 | AFFINITY-TAGGED PHOTOSWITCHES AND METHODS OF USE THEREOF | CD2BP2, AGBL2, CLTB | CYP2A6 4500/4885CYP2E1 4860/4885CYP2B6 4683/4885 |
| US-20230173090-A1 | COMPOSITIONS AND METHODS FOR MODULATING DOPAMINE RECEPTOR ACTIVITY | PARK7, PRLHR, SNCA | CYP2A6 4712/4885CYP2E1 4835/4885CYP2B6 4794/4885 |
| US-20070128662-A1 | Photoreactive regulator of protein function and methods of use thereof | PPP1R10, PPP6R3, ANKRD52 | CYP2A6 4534/4885CYP2E1 4863/4885CYP2B6 4828/4885 |
| US-20110207213-A1 | Photoreactive Synthetic Regulator of Protein Function and Methods of Use Thereof | PPP1R10, PPP6R1, PPP6R3 | CYP2A6 4626/4885CYP2E1 4863/4885CYP2B6 4823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.