Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Famotine SCHEMBL147773 | 0.99 | ALDH1A1 (0.46) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPT | |
| Famotine SCHEMBL32677713 | 0.99 | ALDH1A1 (0.46) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPT | |
| Memotine SCHEMBL29388019 | 0.86 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPT | |
| Memotine SCHEMBL147540 | 0.84 | PKM (0.48) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL28811723 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL7338667 | 0.75 | KDM4E (0.54) | ALDH1A1KDM4ELMNAMAPTPKM | |
| SCHEMBL9815282 | 0.73 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNANOS3NOS2 | |
| Hydrochloric Acid SCHEMBL3452241 | 0.72 | KDM4E (0.57) | ALDH1A1KDM4ELMNAMAPTNOS3 | |
| SCHEMBL29361631 | 0.71 | KDM4E (0.60) | ALDH1A1KDM4ELMNAMAPTNOS3 | |
| SCHEMBL7509399 | 0.71 | KDM4E (0.60) | ALDH1A1KDM4ELMNAMAPTNOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240165086-A1 | COATED FAMOTIDINE PARTICLE | KENVUE BRANDS LLC | 2024-05-23 | — | — | US | claimed |
| EP-4312992-A1 | A PHARMACEUTICAL COMPOSITION COMPRISING FAMOTIDINE | JOHNSON & JOHNSON CONSUMER INC. (US) | 2024-02-07 | — | — | EP | claimed |
| WO-2022200897-A1 | A PHARMACEUTICAL COMPOSITION COMPRISING FAMOTIDINE | JOHNSON & JOHNSON CONSUMER INC. (US) | 2022-09-29 | — | — | WO | claimed |
| US-20210094954-A1 | PREPARATION METHODS AND APPLICATIONS OF 3,5-DISUBSTITUTED METHYLPYRAZOLO[1,5-A]PYRIMIDINE-7-HYDROXYLIC SALTS | XU LIFENG (US) | 2021-04-01 | — | — | US | claimed |
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| US-8637531-B2 | Pyrido(3,2-d)pyridmidines useful for treating viral infections | GILEAD SCIENCES, INC. (US) | 2014-01-28 | — | — | US | claimed |
| US-8232278-B2 | Pyrido(3,2-D)pyrimidines and pharmaceutical compositions useful for treating hepatitis C | GILEAD SCIENCES, INC. (US) | 2012-07-31 | — | — | US | claimed |
| US-20120178915-A1 | PYRIMIDINE DERIVATIVES AND ANALOGS, PREPARATION METHOD AND USE THEREOF | XU LIFENG (US) | 2012-07-12 | — | — | US | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| US-20100048559-A1 | PYRIDO(3,2-d)PYRIDMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | Gilead Science, Inc (US) | 2010-02-25 | — | — | US | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| CN-1871203-A | Composition comprising phenethyl aryl esters as solubilizers for active organic compounds | ISP INVESTMENTS INC (US) | 2006-11-29 | — | — | CN | claimed |
| EP-1608403-A2 | IMMUNOSTIMULATORY NUCLEIC ACID OIL-IN-WATER FORMULATIONS FOR TOPICAL APPLICATION | Coley Pharmaceutical Group, Ltd. (CA) | 2005-12-28 | — | — | EP | claimed |
| CN-1642530-A | Modified release tablet based on microcapsules | FLAMEL TECH SA (FR) | 2005-07-20 | — | — | CN | claimed |
| WO-2004087203-A2 | IMMUNOSTIMULATORY NUCLEIC ACID OIL-IN-WATER FORMULATIONS FOR TOPICAL APPLICATION | COLEY PHARMACEUTICAL GROUP, LTD. (CA) | 2004-10-14 | — | — | WO | claimed |
| EP-1434602-A2 | CPG FORMULATIONS AND RELATED METHODS | Merial Limited (US) | 2004-07-07 | — | — | EP | claimed |
| CN-1147292-C | Double capsule for the administration of active principles in multiple therepies | ������ҩ������˾ | 2004-04-28 | — | — | CN | claimed |
| WO-2003030934-A2 | CPG FORMULATIONS AND RELATED METHODS | MERIAL LIMITED (US) | 2003-04-17 | — | — | WO | claimed |
| CN-1285741-A | Double-layer capsule for administering active ingredients in combination therapy | AXCAN PHARMA INC (CA) | 2001-02-28 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210094954-A1 | PREPARATION METHODS AND APPLICATIONS OF 3,5-DISUBSTITUTED METHYLPYRAZOLO[1,5-A]PYRIMIDINE-7-HYDROXYLIC SALTS | DHPS, NUDT1, DPYD | ALDH1A1 346/4885KDM4E 1087/4885SMN1; SMN2 3400/4885 |
| US-20120178915-A1 | PYRIMIDINE DERIVATIVES AND ANALOGS, PREPARATION METHOD AND USE THEREOF | TYMP, TYMS, ADORA3 | ALDH1A1 572/4885KDM4E 3483/4885SMN1; SMN2 1771/4885 |
| US-20100048559-A1 | PYRIDO(3,2-d)PYRIDMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | PNPO, PLPBP, PDXK | ALDH1A1 1288/4885KDM4E 2887/4885SMN1; SMN2 2611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.