Memotine

Memotine

SCHEMBL29388019

COc1ccc(OCC2=NCCc3ccccc32)cc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
KDM4E B2RXH2 4/20 0.47
PKM P14618 2/20 0.46
LMNA P02545 2/20 0.44
MAOA P21397 1/20 0.44
MAPT P10636 4/20 0.43
HTT P42858 1/20 0.42
NOS3 P29474 1/20 0.41
NOS2 P35228 1/20 0.41
GLA P06280 1/20 0.41
RCE1 Q9Y256 1/20 0.41
SMPD1 P17405 1/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP19A1 P11511 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Memotine SCHEMBL147540 0.99 PKM (0.48) ALDH1A1KDM4EPKMLMNAMAOA
Famotine SCHEMBL600861 0.86 ALDH1A1 (0.47) ALDH1A1KDM4EPKMLMNAMAOA
Famotine SCHEMBL32677713 0.84 ALDH1A1 (0.46) ALDH1A1KDM4EPKMLMNAMAOA
Famotine SCHEMBL147773 0.84 ALDH1A1 (0.46) ALDH1A1KDM4EPKMLMNAMAOA
SCHEMBL7338667 0.82 KDM4E (0.54) ALDH1A1KDM4EPKMLMNAMAOA
SCHEMBL7509399 0.78 KDM4E (0.60) ALDH1A1KDM4ELMNAMAOAMAPT
SCHEMBL29361631 0.78 KDM4E (0.60) ALDH1A1KDM4ELMNAMAOAMAPT
SCHEMBL12567716 0.75 ALDH1A1 (0.65) ALDH1A1PKMLMNAMAOANOS3
SCHEMBL29498350 0.75 ALDH1A1 (0.65) ALDH1A1PKMLMNAMAOANOS3
SCHEMBL29498357 0.75 ALDH1A1 (0.65) ALDH1A1PKMLMNAMAOANOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026043843-A1 TETRAHYDROPYRIMIDINE (THP) IONIZABLE LIPIDS FOR EFFICIENT MRNA DELIVERY THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, (US) 2026-02-26 WO claimed
WO-2024215771-A1 SUBSTITUTED PHENYL ETHYNYL PYRIMIDINES AS POTENT INHIBITORS OF ALPHAVIRUSES SOUTHERN RESEARCH INSTITUTE (US) 2024-10-17 WO claimed
EP-4262812-A1 6-AZA-NUCLEOSIDE PRODRUGS AS ANTIVIRAL AGENTS FOR TREATING VIRUS INFECTIONS Southern Research Institute (US) 2023-10-25 EP claimed
WO-2023122212-A2 SUBSTITUTED PHENYL ETHYNYL PYRIDINE CARBOXAMIDES AS POTENT INHIBITORS OF SARS VIRUS SOUTHERN RESEARCH INSTITUTE (US) 2023-06-29 WO claimed
EP-4125845-A1 NOVEL 2-PYRIMIDONE ANALOGS AS POTENT ANTIVIRAL AGENTS AGAINST ALPHAVIRUSES Southern Research Institute (US) 2023-02-08 EP claimed
EP-4021413-A1 LIPOSOMAL TROPONOID COMPOUND FORMULATIONS United States Government as Represented by The Department of Veterans Affairs (US) 2022-07-06 EP claimed
WO-2022133323-A1 6-AZA-NUCLEOSIDE PRODRUGS AS ANTIVIRAL AGENTS FOR TREATING VIRUS INFECTIONS SOUTHERN RESEARCH INSTITUTE (US) 2022-06-23 WO claimed
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF INSTITUT CURIE (FR) 2026-05-21 US disclosed
WO-2026043843-A1 TETRAHYDROPYRIMIDINE (THP) IONIZABLE LIPIDS FOR EFFICIENT MRNA DELIVERY THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, (US) 2026-02-26 WO disclosed
EP-4092139-B1 METHOD FOR DISCRIMINATING BETWEEN LIVE AND DEAD MICROBES IN A SAMPLE PATHOQUEST (FR) 2026-02-18 EP disclosed
US-12527854-B2 Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof INSTITUT CURIE (FR) 2026-01-20 US disclosed
US-20250144066-A1 Prevention and Treatment of Parasitic Infections BARANOWITZ STEVEN (US) 2025-05-08 US disclosed
WO-2025064458-A1 PREVENTION AND TREATMENT OF VIRAL INFECTIONS BARANOWITZ STEVEN (US) 2025-03-27 WO disclosed
EP-3810811-B1 METHOD FOR DISCRIMINATING BETWEEN LIVE AND DEAD MICROBES IN A SAMPLE PATHOQUEST (FR) 2022-06-15 EP disclosed
US-20220177452-A9 2-Pyrimidone Analogs as Potent Antiviral Agents Against Alphaviruses NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-06-09 US disclosed
WO-2022117764-A1 FUNCTIONALIZED SHIGA TOXIN B-SUBUNIT (STxB) PROTEINS AND CONJUGATES THEREOF INSTITUT CURIE (FR) 2022-06-09 WO disclosed
CN-114502174-A 2,4,7 substituted-7-deaza-2 '-deoxy-2' -fluoroarabinosucleosides and nucleotide prodrugs and use thereof 南方研究院 2022-05-13 CN disclosed
EP-3982976-A2 2,4,7-SUBSTITUTED-7-DEAZA-2'-DEOXY-2'-FLUOROARABINOSYL NUCLEOSIDE AND NUCLEOTIDE PRO-DRUGS AND USES THEREOF Southern Research Institute (US) 2022-04-20 EP disclosed
EP-3980057-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF Institut Curie (FR) 2022-04-13 EP disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527854-B2 Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof STXBP1, RNGTT, UPF1 ALDH1A1 4838/4885KDM4E 2432/4885PKM 4689/4885
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF STXBP1, HBB, UPF1 ALDH1A1 4710/4885KDM4E 2972/4885PKM 4207/4885
US-20250144066-A1 Prevention and Treatment of Parasitic Infections EPX, CTSA, SERPINB1 ALDH1A1 509/4885KDM4E 4297/4885PKM 2375/4885
US-20220177452-A9 2-Pyrimidone Analogs as Potent Antiviral Agents Against Alphaviruses EIF2AK2, ZC3HAV1, MAVS ALDH1A1 492/4885KDM4E 470/4885PKM 981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.