Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Flufenacet. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flufenacet SCHEMBL6061666 | 0.86 | — | — | |
| Flufenacet SCHEMBL6062286 | 0.85 | — | — | |
| Flufenacet SCHEMBL19463450 | 0.78 | MAPT (0.37) | — | |
| SCHEMBL116869 | 0.77 | NPC1 (0.31) | — | |
| Logran SCHEMBL19462948 | 0.75 | MAPT (0.36) | — | |
| Prosulfuron SCHEMBL19464005 | 0.75 | MAPT (0.34) | — | |
| Flufenacet SCHEMBL4897219 | 0.72 | MLYCD (0.34) | — | |
| Flufenacet SCHEMBL116467 | 0.72 | MLYCD (0.34) | — | |
| SCHEMBL7643173 | 0.72 | CDK1 (0.37) | — | |
| Flufenacet SCHEMBL7205592 | 0.71 | MLYCD (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060009359-A1 | Selective heteroaryloxy-acetamide-based herbicides | FEUCHT DIETER | 2006-01-12 | — | — | US | disclosed |
| US-6967188-B2 | Selective heteroaryloxy- acetamides-based herbicides | BAYER CROPSCIENCE AG (DE) | 2005-11-22 | — | — | US | disclosed |
| US-20040102321-A1 | Selective heteroaryloxy- acetamides-based herbicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2004-05-27 | — | — | US | disclosed |