SCHEMBL6136227

SCHEMBL6136227

COc1ccc(Sc2ccccc2)cc1.O=P(O)(O)F.O=P(O)(O)F.O=P(O)(O)F.O=P(O)(O)F.O=P(O)(O)F.O=P(O)(O)F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 2/20 0.52
MMP9 P14780 2/20 0.52
MMP12 P39900 2/20 0.52
ACP3 P15309 3/20 0.51
PTGIR P43119 1/20 0.47
ALDH1A1 P00352 4/20 0.44
HPGD P15428 2/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
CA4 P22748 1/20 0.43
HTT P42858 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
LTA4H P09960 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2272158 0.85 CA4 (0.59) MMP2MMP9MMP12PTGIRALDH1A1
SCHEMBL6482376 0.79 ALDH1A1 (0.58) MMP2MMP9MMP12PTGIRALDH1A1
SCHEMBL482369 0.77 CA1 (0.65) PTGIRALDH1A1NPC1RAB9ACA4
SCHEMBL29870046 0.76 CES2 (0.62) PTGIRALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL12757105 0.76 CES2 (0.62) PTGIRALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL29798085 0.76 MMP2 (0.56) MMP2MMP9MMP12PTGIRALDH1A1
Diphenylsulfane SCHEMBL30630125 0.76 HPGD (0.42) ALDH1A1HPGDSMN1; SMN2MEN1KMT2A
SCHEMBL13397754 0.76 HTT (0.49) MMP2MMP9MMP12ACP3PTGIR
SCHEMBL11295113 0.76 LMNA (0.55) PTGIRALDH1A1HPGDNPC1RAB9A
SCHEMBL8944222 0.75 CA4 (0.46) MMP2MMP9MMP12PTGIRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1035439-B1 Photosensitive resin composition, color filter, and copolymer resin useful for them DAINIPPON PRINTING CO LTD (JP) 2005-06-15 EP disclosed
US-6517980-B2 Copolymer containing hydroxyalkyl meth(acrylate), a (meth)acrylic acid having been partially reacted through carboxy group and hydroxyalkyl(meth)acrylate reacted through hydroxy group with (meth)acryloylalkyl isocyanate compound DAI NIPPON PRINTING CO., LTD. (JP) 2003-02-11 US disclosed
US-20020172873-A1 Photosensitive resin composition, color filter, and copolymer resin useful for them DAI NIPPON PRINTING CO., LTD. (JP) 2002-11-21 US disclosed
US-6410206-B1 MIXTURE OF (METH)ACRYLIC ACID, ACRYLATED ESTER AND EPOXYCOMPOUND DAI NIPPON PRINTING CO., LTD. (JP) 2002-06-25 US disclosed
EP-1035439-A2 Photosensitive resin composition, color filter, and copolymer resin useful for them DAI NIPPON PRINTING CO., LTD. (JP) 2000-09-13 EP disclosed