Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585603 | 0.97 | ALDH1A1 (0.38) | TSHRALDH1A1 | |
| SCHEMBL213230 | 0.95 | — | — | |
| SCHEMBL613409 | 0.83 | — | — | |
| SCHEMBL1539189 | 0.81 | TSHR (0.35) | TSHRALDH1A1TDP1 | |
| SCHEMBL17669021 | 0.80 | LMNA (0.32) | — | |
| SCHEMBL22110202 | 0.78 | TSHR (0.40) | TSHRALDH1A1TDP1 | |
| SCHEMBL18973981 | 0.77 | ALDH1A1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL3093333 | 0.77 | ALDH1A1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL18037938 | 0.77 | — | — | |
| SCHEMBL17669025 | 0.77 | MEN1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114262302-B | Method for synthesizing diisocyanate trimer, catalyst and preparation method thereof | 山东新和成维生素有限公司 | 2023-09-29 | — | — | CN | claimed |
| CN-109174048-B | Silica gel chromatographic packing and preparation method thereof | 月旭科技（上海）股份有限公司 | 2021-12-28 | — | — | CN | claimed |
| CN-111234315-A | Sulfur-containing silane coupling agent releasing low-level VOC in use and preparation method thereof | 南京曙光精细化工有限公司 | 2020-06-05 | — | — | CN | claimed |
| US-10221200-B2 | Quaternary amino alcohol functional organosilicon compounds, composition containing the latter and their production and use | EVONIK DEGUSSA GMBH (DE) | 2019-03-05 | — | — | US | claimed |
| EP-2785726-B1 | ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF; AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS | DOW SILICONES CORP (US) | 2018-08-01 | — | — | EP | claimed |
| US-9884879-B2 | Method of synthesizing siloxane monomers and use thereof | SILECS OY (FI) | 2018-02-06 | — | — | US | claimed |
| US-9796738-B2 | Quaternary amino alcohol functional organosilicon compounds, composition containing the latter and their production and use | EVONIK DEGUSSA GMBH (DE) | 2017-10-24 | — | — | US | claimed |
| US-20170233416-A1 | Quaternary amino alcohol functional organosilicon compounds, composition containing the latter and their production and use | EVONIK DEGUSSA GMBH (DE) | 2017-08-17 | — | — | US | claimed |
| US-20170088565-A1 | Method of synthesizing siloxane monomers and use thereof | SILECS OY (FI) | 2017-03-30 | — | — | US | claimed |
| EP-2590988-B1 | QUATERNARY AMINO ALCOHOL FUNCTIONAL ORGANOSILICON COMPOUNDS, COMPOSITION CONTAINING THE LATTER AND THEIR PRODUCTION AND USE | EVONIK DEGUSSA GMBH (DE) | 2017-03-01 | — | — | EP | claimed |
| US-20140249326-A1 | Method of Synthesizing Siloxane Monomers and Use Thereof | SILECS OY (FI) | 2014-09-04 | — | — | US | claimed |
| US-8728225-B2 | Composition containing quaternary amino-functional organosilicon compounds and production and use thereof | EVONIK DEGUSSA GMBH (DE) | 2014-05-20 | — | — | US | claimed |
| US-20130167754-A1 | QUATERNARY AMINO ALCOHOL FUNCTIONAL ORGANOSILICON COMPOUNDS, COMPOSITION CONTAINING THE LATTER AND THEIR PRODUCTION AND USE | EVONIK DEGUSSA GMBH (DE) | 2013-07-04 | — | — | US | claimed |
| WO-2012172176-A9 | METHOD OF SYNTHESIZING SILOXANE MONOMERS AND USE THEREOF | SILECS OY (FI) | 2013-02-07 | — | — | WO | claimed |
| WO-2012172176-A2 | METHOD OF SYNTHESIZING SILOXANE MONOMERS AND USE THEREOF | SILECS OY (FI) | 2012-12-20 | — | — | WO | claimed |
| US-20120037040-A1 | COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF | EVONIK DEGUSSA GMBH (DE) | 2012-02-16 | — | — | US | claimed |
| US-20070087025-A1 | Reiteratively layered medical devices and method of preparing same | FITZHUGH ANTHONY | 2007-04-19 | — | — | US | claimed |
| EP-1436018-A1 | NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2004-07-14 | — | — | EP | claimed |
| WO-2003026717-A1 | NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2003-04-03 | — | — | WO | claimed |
| US-5446181-A | Method and apparatus for preparing 3-[N-(2-aminoethyl)]aminopropylalkoxysilane | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-08-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070087025-A1 | Reiteratively layered medical devices and method of preparing same | NOS2, NOS1, NOS3 | TSHR 2005/4885ALDH1A1 2127/4885TDP1 1589/4885 |
| US-20130167754-A1 | QUATERNARY AMINO ALCOHOL FUNCTIONAL ORGANOSILICON COMPOUNDS, COMPOSITION CONTAINING THE LATTER AND THEIR PRODUCTION AND USE | BCAT2, BCAT1, ADH5 | TSHR 4879/4885ALDH1A1 273/4885TDP1 1226/4885 |
| US-20170088565-A1 | Method of synthesizing siloxane monomers and use thereof | MSMO1, PCNA, PIEZO1 | TSHR 4868/4885ALDH1A1 345/4885TDP1 3850/4885 |
| US-20140249326-A1 | Method of Synthesizing Siloxane Monomers and Use Thereof | MSMO1, PCNA, PIEZO1 | TSHR 4868/4885ALDH1A1 345/4885TDP1 3850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.