Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARK7 | Q99497 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 5/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159481 | 0.84 | OPRL1 (0.44) | PARK7KCNH2CACNA1GOPRM1OPRL1 | |
| SCHEMBL8211064 | 0.77 | CACNA1G (0.39) | MEN1KMT2ACACNA1G | |
| SCHEMBL6160083 | 0.77 | MEN1 (0.50) | KCNH2HTR1ASLC6A4MEN1KMT2A | |
| SCHEMBL6159478 | 0.73 | SLC18A3 (0.47) | — | |
| SCHEMBL13898484 | 0.71 | SIGMAR1 (0.47) | HTR1AMEN1KMT2A | |
| SCHEMBL7723133 | 0.71 | HTR1A (0.50) | HTR1ASLC6A4MEN1KMT2AOPRM1 | |
| SCHEMBL8220653 | 0.71 | SLC18A3 (0.43) | CACNA1G | |
| SCHEMBL6164719 | 0.70 | HTR2C (0.58) | HTR1ASLC6A4HTR2C | |
| SCHEMBL6162560 | 0.68 | DRD2 (0.45) | PARK7HTR1AHTR7 | |
| SCHEMBL20494904 | 0.66 | HTR2C (0.51) | HTR1ASLC6A4HTR7HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755923-B1 | Ameliorant or remedy for symptoms caused by Ischemic diseases and Phenylpiperidine compounds useful therefor | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |