Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2587720 | 0.82 | ALDH1A1 (0.44) | LMNAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL64436 | 0.82 | ALDH1A1 (0.63) | LMNAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28051 | 0.81 | PSIP1 (0.47) | LMNAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10700258 | 0.79 | LMNA (0.45) | LMNAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5664985 | 0.79 | HTR6 (0.47) | ALDH1A1CYP3A4CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL28166558 | 0.79 | ALDH1A1 (0.59) | LMNAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28865930 | 0.79 | ALDH1A1 (0.38) | LMNAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28932041 | 0.79 | ALDH1A1 (0.38) | LMNAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL82994 | 0.78 | CA1 (0.44) | LMNAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL453331 | 0.78 | MMP1 (0.50) | ALDH1A1CYP3A4CYP2C9CYP2C19CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199681-A1 | OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS | EVONETIX LTD (GB) | 2024-06-20 | — | — | US | claimed |
| WO-2024110477-A2 | SYNTHESIS OF A CYCLIC PEPTIDE | JANSSEN PHARMACEUTICA NV (BE) | 2024-05-30 | — | — | WO | claimed |
| WO-2024081372-A1 | PROCESSES FOR THE PREPARATION OF THE AGENT-LINKER CONJUGATE CL2A-SN-38 AND THE IMMUNOCONJUGATES SACITUZUMAB GOVITECAN AND LABETUZUMAB GOVETICAN | GILEAD SCIENCES, INC. (US) | 2024-04-18 | — | — | WO | claimed |
| US-20230235328-A1 | NOVEL MORPHOLINO OLIGONUCLEOTIDE DERIVATIVES | Nexoligo Co., Ltd. (KR) | 2023-07-27 | — | — | US | claimed |
| WO-2023039068-A1 | COMPOSITIONS AND METHODS FOR SYNTHESIS OF PEPTIDE NUCLEIC ACID INTERMEDIATES | NEUBASE THERAPEUTICS, INC. (US) | 2023-03-16 | — | — | WO | claimed |
| EP-4140988-A1 | L-VALINATE OF HYDROXYPROPYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVE AND SALT FORM, CRYSTAL POLYMORPH THEREOF | Merck Serono S.A. (CH) | 2023-03-01 | — | — | EP | claimed |
| EP-3720854-B1 | SOLID PHASE SYNTHESIS OF NIR FLUORESCENT PROBE | BRACCO IMAGING SPA (IT) | 2021-04-21 | — | — | EP | claimed |
| US-20210047361-A1 | OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS | SILICON VALLEY BANK | 2021-02-18 | — | — | US | claimed |
| EP-3743433-A1 | OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS | Evonetix Ltd (GB) | 2020-12-02 | — | — | EP | claimed |
| US-10822371-B2 | Solid phase synthesis of NIR fluorescent probe | BRACCO IMAGING S.P.A. (IT) | 2020-11-03 | — | — | US | claimed |
| EP-3720854-A1 | SOLID PHASE SYNTHESIS OF NIR FLUORESCENT PROBE | Bracco Imaging SpA (IT) | 2020-10-14 | — | — | EP | claimed |
| US-20200317722-A1 | SOLID PHASE SYNTHESIS OF NIR FLUORESCENT PROBE | BRACCO IMAGING S.P.A. (IT) | 2020-10-08 | — | — | US | claimed |
| WO-2019145713-A9 | OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS | EVONETIX LTD (GB) | 2020-08-06 | — | — | WO | claimed |
| EP-3609866-A1 | THERMALLY-CLEAVABLE PROTECTING AND LINKER GROUPS | Evonetix Ltd (GB) | 2020-02-19 | — | — | EP | claimed |
| WO-2019145713-A1 | OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS | EVONETIX LTD (GB) | 2019-08-01 | — | — | WO | claimed |
| WO-2019110639-A1 | SOLID PHASE SYNTHESIS OF NIR FLUORESCENT PROBE | BRACCO IMAGING SPA (IT) | 2019-06-13 | — | — | WO | claimed |
| EP-3400217-A1 | L-VALINATE OF HYDROXYPROPYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVE AND SALT FORM, CRYSTAL POLYMORPH THEREOF | Merck Serono S.A. (CH) | 2018-11-14 | — | — | EP | claimed |
| WO-2018189546-A1 | THERMALLY-CLEAVABLE PROTECTING AND LINKER GROUPS | EVONETIX LTD (GB) | 2018-10-18 | — | — | WO | claimed |
| US-9834528-B2 | Alpha-amino esters of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof | MERCK SERONO S.A. (CH) | 2017-12-05 | — | — | US | claimed |
| WO-2017118641-A1 | L-VALINATE OF HYDROXYPROPYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVE AND SALT FORM, CRYSTAL POLYMORPH THEREOF | MERCK SERONO S.A. (CH) | 2017-07-13 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230235328-A1 | NOVEL MORPHOLINO OLIGONUCLEOTIDE DERIVATIVES | RNGTT, MPO, RNMT | LMNA 3274/4885ALDH1A1 2537/4885CYP3A4 4320/4885 |
| US-20200317722-A1 | SOLID PHASE SYNTHESIS OF NIR FLUORESCENT PROBE | MKI67, SSTR5, AURKA | LMNA 3265/4885ALDH1A1 3804/4885CYP3A4 665/4885 |
| US-20240199681-A1 | OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS | POLN, POLI, ADAR | LMNA 319/4885ALDH1A1 4015/4885CYP3A4 4190/4885 |
| US-10822371-B2 | Solid phase synthesis of NIR fluorescent probe | MKI67, SSTR5, AURKA | LMNA 3265/4885ALDH1A1 3804/4885CYP3A4 665/4885 |
| US-20210047361-A1 | OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS | POLN, POLI, ADAR | LMNA 319/4885ALDH1A1 4015/4885CYP3A4 4190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.