SCHEMBL6201505

SCHEMBL6201505

O=C1C=c2ccccc2=CC1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CFTR P13569 1/20 0.35
GOPC Q9HD26 1/20 0.35
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8917621 0.98 CFTR (0.34) CFTRGOPC
SCHEMBL4709428 0.78 GSTP1 (0.36) CYP2A6
SCHEMBL3244825 0.74 GSTP1 (0.34)
SCHEMBL10474054 0.72 MAOA (0.34)
SCHEMBL18849437 0.70
SCHEMBL31656985 0.68 ALDH1A1 (0.38)
SCHEMBL31657027 0.68 ALDH1A1 (0.38)
SCHEMBL31657085 0.68 ALDH1A1 (0.38)
SCHEMBL6828416 0.66 BACE1 (0.43)
SCHEMBL2230292 0.66 MAPT (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116807912-A Use of volatile components to limit or eliminate perception of malodor 弗门尼舍有限公司 2023-09-29 CN claimed
CN-110198949-B Process for the preparation of 9 beta, 10 alpha-progesterone (retroprogesterone) 工业化学有限公司 2022-05-10 CN claimed
CN-107188874-A A kind of synthetic method of chiral quaternary carbon compound 浙江工业大学 2017-09-22 CN claimed
EP-2961374-B1 FRAGRANCE COMPOSITIONS PROCTER & GAMBLE (US) 2017-01-25 EP claimed
CN-103709162-B Tri-substituted imidazole benzodiazine ketonic compound and its production and use 中国科学院上海药物研究所 2016-12-07 CN claimed
WO-1998029136-A1 STABILIZED TRICYCLIC COMPOUND TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-07-09 WO claimed
US-12508218-B2 Coating compositions COTY INC. (US) 2025-12-30 US disclosed
EP-3103523-B1 ABSORBENT ARTICLE COMPRISING FRAGRANCE COMPOSITION PROCTER & GAMBLE (US) 2025-10-29 EP disclosed
US-20250127707-A1 FRAGRANCE FORMULATION COTY INC. 2025-04-24 US disclosed
US-20250127694-A1 FRAGRANCE COMPOSITIONS AND USES THEREOF COTY INC. 2025-04-24 US disclosed
CN-116036278-B Compositions and methods for treating cancers with atypical BRAF mutations 生物医学谷探索股份有限公司 2024-12-17 CN disclosed
US-20240287406-A1 FRAGRANCE COMPOSITION COTY INC. 2024-08-29 US disclosed
EP-4362924-A1 FRAGRANCE COMPOSITION Coty Inc. (US) 2024-05-08 EP disclosed
EP-1492795-A1 1- OR 3-THIA-BENZONAPHTHOAZULENES AS INHIBITORS OF TUMOUR NECROSIS FACTOR PRODUCTION AND INTERMEDIATES FOR THE PREPARATION THEREOF PLIVA-ISTRAZIVACKI INSTITUT d.o.o. (HR) 2005-01-05 EP disclosed
WO-2003084961-A1 1- OR 3-THIA-BENZONAPHTHOAZULENES AS INHIBITORS OF TUMOUR NECROSIS FACTOR PRODUCTION AND INTERMEDIATES FOR THE PREPARATION THEREOF PLIVA-ISTRAZIVACKI INSTITUT D.O.O. (HR) 2003-10-16 WO disclosed
WO-1998029136-A1 STABILIZED TRICYCLIC COMPOUND TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-07-09 WO disclosed
US-5770382-A RETINOIC ACID AND RETINOID X RECEPTOR AGONISTS; TREATINGSKIN, EYE, BRAIN, AND CARDIOVASCULAR DISORDERS; CANCER LIGAND PHARMACEUTICALS, INC. (US) 1998-06-23 US disclosed
US-5770378-A A VITAMINE A METABOLITE, POTENT DRUGS TREATING SKIN DISEASES, CANCER, EYE DISEASES, CARDIOVASCULAR DISORDERS LIGAND PHARMACEUTICALS, INC. (US) 1998-06-23 US disclosed
US-5770383-A ACTIVATE RETINOID RECEPTORS LIGAND PHARMACEUTICALS, INC. (US) 1998-06-23 US disclosed
EP-0049953-B1 4-(SUBSTITUTED PHENYL)-NAPHTHALEN-2(1H)-ONES AND 2-OLS, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM PFIZER INC. (US) 1984-05-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250127694-A1 FRAGRANCE COMPOSITIONS AND USES THEREOF TRPA1, TRPV1, NAA40 CFTR 1563/4885GOPC 2298/4885CYP2A6 4003/4885
US-20250127707-A1 FRAGRANCE FORMULATION PUF60, POLM, ADH5 CFTR 2608/4885GOPC 3212/4885CYP2A6 1896/4885
US-20240287406-A1 FRAGRANCE COMPOSITION FAAH2, FAAH, C1S CFTR 2164/4885GOPC 3557/4885CYP2A6 858/4885
US-12508218-B2 Coating compositions TAS2R40, TAS2R20, TAS2R10 CFTR 672/4885GOPC 984/4885CYP2A6 3143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.