SCHEMBL6209012

SCHEMBL6209012

CCC(CO)NC(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
CNR1 P21554 1/20 0.50
ADRA1A P35348 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
KDM4E B2RXH2 1/20 0.50
ABCC3 O15438 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
TSHR P16473 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6209009 1.00 LMNA (0.50) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL10245268 1.00 LMNA (0.50) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL437046 0.86 LMNA (0.38) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL3954367 0.83 LMNA (0.33) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL10245473 0.80 TSHR (0.39) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL10246425 0.80 TSHR (0.39) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL10246446 0.80 TSHR (0.39) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL21371585 0.78 LMNA (0.31) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL26306505 0.77 LMNA (0.48) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL14266734 0.77 ALDH1A1 (0.41) LMNACNR1ADRA1ATDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3903909-B1 REMOVAL OF HYDROGEN SULPHIDE AND CARBON DIOXIDE FROM A FLUID FLOW BASF SE (DE) 2024-06-19 EP disclosed
US-11278841-B2 Removal of hydrogen sulphide and carbon dioxide from a stream of fluid BASF SE (DE) 2022-03-22 US disclosed
EP-3903909-A1 REMOVAL OF HYDROGEN SULPHIDE AND CARBON DIOXIDE FROM A FLUID FLOW BASF SE (DE) 2021-11-03 EP disclosed
EP-3185989-B1 REMOVAL OF HYDROGEN SULPHIDE AND CARBON DIOXIDE FROM A STREAM OF FLUID BASF SE (DE) 2021-08-11 EP disclosed
CN-106794414-B Removal of hydrogen sulfide and carbon dioxide from fluid streams 巴斯夫欧洲公司 2020-11-06 CN disclosed
US-10519160-B2 Imaging agents for neural flux THE GENERAL HOSPITAL CORPORATION (US) 2019-12-31 US disclosed
US-20190134557-A1 REMOVAL OF HYDROGEN SULPHIDE AND CARBON DIOXIDE FROM A STREAM OF FLUID BASF SE (DE) 2019-05-09 US disclosed
US-10207217-B2 Removal of hydrogen sulphide and carbon dioxide from a stream of fluid BASF SE (DE) 2019-02-19 US disclosed
US-20180222882-A1 PYRIDAZINE DERIVATIVES AS RORc MODULATORS GENENTECH, INC. (US) 2018-08-09 US disclosed
US-20170282115-A1 REMOVAL OF HYDROGEN SULPHIDE AND CARBON DIOXIDE FROM A STREAM OF FLUID BASF SE (DE) 2017-10-05 US disclosed
US-20150148344-A1 QUINOLINE DERIVATIVES AS BROMODOMAIN INHIBITORS GILEAD SCIENCES, INC. 2015-05-28 US disclosed
US-8097708-B2 10a-Azalide compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2012-01-17 US disclosed
US-20090281292-A1 10a-Azalide Compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2009-11-12 US disclosed
US-7557110-B2 MAPKAP-K2; inflammatory disease, autoimmune disease, destructive bone disorder, cancer and/or tumour growth; 5-[(trans-4-aminocyclohexyl)amino]-3-fluoro-6-methyl(pyrazolo[1,5-a]pyri- midin-7-yl)}(4-iodophenyl)amine TEIJIN PHARMA LIMITED (JP) 2009-07-07 US disclosed
US-7557110-B2 MAPKAP-K2; inflammatory disease, autoimmune disease, destructive bone disorder, cancer and/or tumour growth; 5-[(trans-4-aminocyclohexyl)amino]-3-fluoro-6-methyl(pyrazolo[1,5-a]pyri- midin-7-yl)}(4-iodophenyl)amine TEIJIN PHARMA LIMITED (JP) 2009-07-07 US disclosed
US-20070293511-A1 Crf Receptor Antagonists and Methods SB PHARMCO PUERTO RICO INC. AND NEUROCRINE BIOSCIENCES, INC., A CORPORATION 2007-12-20 US disclosed
EP-1401443-A4 NOVEL ANTI-INFECTIVES SMITHKLINE BEECHAM CORP (US) 2005-10-26 EP disclosed
US-20040147739-A1 Novel anti-infectives SMITHKLINE BEECHAM CORPORATION 2004-07-29 US disclosed
EP-1401443-A1 NOVEL ANTI-INFECTIVES SMITHKLINE BEECHAM CORPORATION (US) 2004-03-31 EP disclosed
WO-2002098424-A1 NOVEL ANTI-INFECTIVES SMITHKLINE BEECHAM CORPORATION (US) 2002-12-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180222882-A1 PYRIDAZINE DERIVATIVES AS RORc MODULATORS RORC, RORB, RORA LMNA 1681/4885CNR1 31/4885ADRA1A 106/4885
US-20170282115-A1 REMOVAL OF HYDROGEN SULPHIDE AND CARBON DIOXIDE FROM A STREAM OF FLUID C1R, MSRB3, HRH4 LMNA 4861/4885CNR1 18/4885ADRA1A 1842/4885
US-20070293511-A1 Crf Receptor Antagonists and Methods CRHR1, CRHR2, CRH LMNA 3690/4885CNR1 13/4885ADRA1A 100/4885
US-20150148344-A1 QUINOLINE DERIVATIVES AS BROMODOMAIN INHIBITORS BRD4, BRD7, BRD3 LMNA 1213/4885CNR1 438/4885ADRA1A 2582/4885
US-20040147739-A1 Novel anti-infectives RPL5, RPL7, RPL35 LMNA 4806/4885CNR1 2864/4885ADRA1A 3690/4885
US-11278841-B2 Removal of hydrogen sulphide and carbon dioxide from a stream of fluid C1R, MSRB3, HRH4 LMNA 4860/4885CNR1 18/4885ADRA1A 1851/4885
US-10207217-B2 Removal of hydrogen sulphide and carbon dioxide from a stream of fluid C1R, MSRB3, HRH4 LMNA 4861/4885CNR1 18/4885ADRA1A 1842/4885
US-20190134557-A1 REMOVAL OF HYDROGEN SULPHIDE AND CARBON DIOXIDE FROM A STREAM OF FLUID C1R, MSRB3, HRH4 LMNA 4861/4885CNR1 18/4885ADRA1A 1842/4885
US-10519160-B2 Imaging agents for neural flux SLC18A2, SLC18A3, PMP22 LMNA 2315/4885CNR1 122/4885ADRA1A 1623/4885
US-20090281292-A1 10a-Azalide Compound IL17A, AZI2, HDAC9 LMNA 1467/4885CNR1 4356/4885ADRA1A 3144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.