SCHEMBL6239437

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6231939	0.86	RAB9A (0.60)	TDP1ALDH1A1MAPTKEAP1NFE2L2
	SCHEMBL14988369	0.83	NPC1 (0.50)	KMT2AMEN1TDP1ALDH1A1MAPT
	SCHEMBL1723569	0.82	MAPT (0.57)	KMT2AMEN1ALDH1A1MAPTNPC1
	SCHEMBL6237830	0.82	RAB9A (0.57)	KMT2AMEN1ALDH1A1MAPTNPBWR1
	SCHEMBL2130063	0.81	ALDH1A1 (0.56)	KMT2AMEN1TDP1ALDH1A1MAPT
	SCHEMBL2488221	0.81	ALDH1A1 (0.56)	KMT2AMEN1TDP1ALDH1A1MAPT
	SCHEMBL6510195	0.81	MAPT (0.54)	KMT2AMEN1TDP1ALDH1A1MAPT
	SCHEMBL71038	0.80	LMNA (0.54)	KMT2AMEN1TDP1ALDH1A1MAPT
	SCHEMBL2029610	0.79	TP53 (0.58)	TDP1ALDH1A1MAPTKEAP1NFE2L2
	Hydrochloric Acid SCHEMBL27598115	0.79	LMNA (0.53)	KMT2AMEN1TDP1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.