Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | DRD3 | P35462 | 3/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20284453 | 0.81 | KMT2A (0.55) | ALDH1A1KDM4ETSHRHTTSMN1; SMN2 | |
| SCHEMBL6357734 | 0.78 | SOD1 (0.71) | ALDH1A1TSHRHTTLMNAMEN1 | |
| SCHEMBL6353873 | 0.77 | DRD4 (0.74) | ALDH1A1KDM4ETSHRHTTSMN1; SMN2 | |
| SCHEMBL18937881 | 0.75 | PPARA (0.54) | MEN1KMT2ADRD2DRD3HTR1A | |
| SCHEMBL10833664 | 0.74 | DRD2 (0.61) | ALDH1A1TSHRSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL31121525 | 0.73 | LOXL2 (0.54) | ALDH1A1KDM4ETSHRHTTSMN1; SMN2 | |
| SCHEMBL30831999 | 0.73 | ALDH1A1 (0.43) | ALDH1A1KDM4ETSHRHTTSMN1; SMN2 | |
| SCHEMBL6202951 | 0.73 | LMNA (0.68) | ALDH1A1TSHRHTTSMN1; SMN2LMNA | |
| SCHEMBL6350328 | 0.73 | KDM4E (1.00) | ALDH1A1KDM4ETSHRHTTSMN1; SMN2 | |
| SCHEMBL20271113 | 0.72 | SLC27A1 (0.59) | ALDH1A1KDM4ETSHRHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176727-A1 | Oximes and hydrazones that are useful in treating sexual dysfunction | ABBOTT LABORATORIES | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176727-A1 | Oximes and hydrazones that are useful in treating sexual dysfunction | CYP19A1, SHBG, CYP17A1 | ALDH1A1 199/4885KDM4E 1593/4885TSHR 2752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.