Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 10/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204074 | 0.90 | MDM2 (0.41) | PTPN1MDM2EP300 | |
| SCHEMBL6202557 | 0.76 | VNN1 (0.51) | NPC1RAB9AL3MBTL1MAPTCYP1A2 | |
| SCHEMBL6204081 | 0.75 | CYP2C9 (0.42) | L3MBTL1MAPTCYP1A2 | |
| SCHEMBL3371893 | 0.75 | FFAR2 (0.42) | L3MBTL1CYP1A2EP300 | |
| SCHEMBL6204077 | 0.70 | MGAM (0.50) | NPC1RAB9AL3MBTL1MAPTHSD11B1 | |
| SCHEMBL6203529 | 0.67 | TSHR (0.52) | MAPTCYP1A2PTPN1 | |
| SCHEMBL571046 | 0.66 | L3MBTL1 (0.85) | NPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL11307784 | 0.66 | MDM2 (0.51) | L3MBTL1MAPTMDM2 | |
| SCHEMBL6201491 | 0.65 | TSHR (0.50) | L3MBTL1MAPTCYP1A2 | |
| Hydrochloric Acid SCHEMBL28260371 | 0.65 | L3MBTL1 (0.82) | NPC1RAB9AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |