Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6401055 | 0.85 | TTR (0.36) | CA2F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6405654 | 0.85 | TTR (0.36) | CA2F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6400356 | 0.85 | CA2 (0.33) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL11688527 | 0.81 | CYP1A2 (0.33) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL11690379 | 0.80 | — | — | |
| SCHEMBL11690387 | 0.75 | GAA (0.30) | — | |
| SCHEMBL11689308 | 0.72 | — | — | |
| SCHEMBL11688529 | 0.68 | SLC2A1 (0.32) | — | |
| SCHEMBL7175125 | 0.66 | CA2 (0.47) | CA2F2PRSS1PRSS2PRSS3 | |
| SCHEMBL5720805 | 0.66 | CA2 (0.70) | CA2F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050130251-A1 | Reagent for determination of hydrogen peroxide | KYOWA MEDEX CO., LTD. (JP) | 2005-06-16 | — | — | US | disclosed |
| EP-1424554-A1 | REAGENT FOR DETERMINING HYDROGEN PEROXIDE | KYOWA MEDEX CO., LTD. (JP) | 2004-06-02 | — | — | EP | disclosed |
| US-4013635-A | COLOR DIFFUSION TRANSFER PHOTOGRAPHY | EASTMAN KODAK COMPANY (US) | 1977-03-22 | — | — | US | disclosed |
| US-4001204-A | Magenta image-providing phenylazonaphthyl dues containing a morpholinyl of piperidine radical | EASTMAN KODAK COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
| US-3954476-A | Diffusable dye-releasing compounds which are cleavable upon oxidation | EASTMAN KODAK COMPANY (US) | 1976-05-04 | — | — | US | disclosed |
| US-3932380-A | DIFFUSION TRANSFER COLOR PHOTOGRAPHY | EASTMAN KODAK COMPANY (US) | 1976-01-13 | — | — | US | disclosed |